Results 21 to 30 of about 22,135,367 (247)

Virus Bioinformatics [PDF]

open access: yes, 2020
Since the discovery of computers, bioinformatics and computational biology have been instrumental in a wide range of discoveries in virology. These include early mathematical models of virus-host interaction, and more recently the analysis of viral ...
Martin Hölzer   +16 more
core   +2 more sources

Bioinformatics: an overview for cancer research [PDF]

open access: yes, 2012
Bioinformatics is a new science that is glowing out in the recent years. It is a multidisciplinary science that is made out of different kinds of other scientific fields like biology, computer science, chemistry, statistics, mathematics and others.
Lu, Joan, Al-Rajab, Murad
core   +3 more sources

Bioinformatic analysis of proteomics data [PDF]

open access: yesBMC Systems Biology, 2014
Most biochemical reactions in a cell are regulated by highly specialized proteins, which are the prime mediators of the cellular phenotype. Therefore the identification, quantitation and characterization of all proteins in a cell are of utmost importance to understand the molecular processes that mediate cellular physiology.
Andreas Schmidt 0009   +2 more
openaire   +4 more sources

Data mining in bioinformatics using Weka [PDF]

open access: yes, 2004
The Weka machine learning workbench provides a general purpose environment for automatic classification, regression, clustering and feature selection-common data mining problems in bioinformatics research.
Ian H. Witten   +9 more
core   +2 more sources

Identification of common oncogenic and early developmental pathways in the ovarian carcinomas controlling by distinct prognostically significant microRNA subsets

open access: yesBMC Genomics, 2017
Background High-grade serous ovarian carcinoma (HG-SOC) is the dominant tumor histologic type in epithelial ovarian cancers, exhibiting highly aberrant microRNA expression profiles and diverse pathways that collectively determine the disease ...
Vladimir A. Kuznetsov   +2 more
doaj   +1 more source

IMPLANT: a new technique for transgene copy number estimation in plants using a single end-point PCR reaction

open access: yesPlant Methods, 2022
Background Copy number determination is one of the first steps in the characterization of transgenic plant lines. The classical approach to this, Southern blotting, is time-consuming, expensive and requires massive amounts of high-quality genomic DNA ...
Jonas De Saeger   +6 more
doaj   +1 more source

The DBCLS BioHackathon: standardization and interoperability for bioinformatics web services and workflows. The DBCLS BioHackathon Consortium* [PDF]

open access: yes, 2010
Web services have become a key technology for bioinformatics, since life science databases are globally decentralized and the exponential increase in the amount of available data demands for efficient systems without the need to transfer entire databases
Kuhn, Michael   +174 more
core   +1 more source

Comparative Genome Analysis of 33 Chlamydia Strains Reveals Characteristic Features of Chlamydia Psittaci and Closely Related Species

open access: yesPathogens, 2020
To identify genome-based features characteristic of the avian and human pathogen Chlamydia (C.) psittaci and related chlamydiae, we analyzed whole-genome sequences of 33 strains belonging to 12 species. Using a novel genome analysis tool termed Roary ILP
Martin Hölzer   +9 more
doaj   +1 more source

Bioinformatics analysis of alternative splicing [PDF]

open access: yesBriefings in Bioinformatics, 2005
Over the past few years, the analysis of alternative splicing using bioinformatics has emerged as an important new field, and has significantly changed our view of genome function. One exciting front has been the analysis of microarray data to measure alternative splicing genome-wide.
Christopher J. Lee, Qi Wang 0073
openaire   +3 more sources

Bi-directional gene set enrichment and canonical correlation analysis identify key diet-sensitive pathways and biomarkers of metabolic syndrome. [PDF]

open access: yes, 2010
peer-reviewedBackground Currently, a number of bioinformatics methods are available to generate appropriate lists of genes from a microarray experiment.
Morine Melissa J   +23 more
core   +1 more source

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