Guide to Metabolomics Analysis: A Bioinformatics Workflow [PDF]
Metabolomics is an emerging field that quantifies numerous metabolites systematically. The key purpose of metabolomics is to identify the metabolites corresponding to each biological phenotype, and then provide an analysis of the mechanisms involved ...
En-Min Li, Li-Yan Xu, Yang Chen
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Bioinformatic analysis of the nucleolus [PDF]
The nucleolus is a plurifunctional, nuclear organelle, which is responsible for ribosome biogenesis and many other functions in eukaryotes, including RNA processing, viral replication and tumour suppression. Our knowledge of the human nucleolar proteome has been expanded dramatically by the two recent MS studies on isolated nucleoli from HeLa cells ...
Leung, Anthony K.L. +3 more
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Coronavirus Genomics and Bioinformatics Analysis [PDF]
The drastic increase in the number of coronaviruses discovered and coronavirus genomes being sequenced have given us an unprecedented opportunity to perform genomics and bioinformatics analysis on this family of viruses. Coronaviruses possess the largest genomes (26.4 to 31.7 kb) among all known RNA viruses, with G + C contents varying from 32% to 43%.
Woo, PCY, Lau, SKP, Yuen, KY, Huang, Y
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Since the discovery of computers, bioinformatics and computational biology have been instrumental in a wide range of discoveries in virology. These include early mathematical models of virus-host interaction, and more recently the analysis of viral ...
Martin Hölzer +16 more
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Bioinformatics analysis of alternative splicing [PDF]
Over the past few years, the analysis of alternative splicing using bioinformatics has emerged as an important new field, and has significantly changed our view of genome function. One exciting front has been the analysis of microarray data to measure alternative splicing genome-wide.
Christopher J. Lee, Qi Wang 0073
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The SIB Swiss Institute of Bioinformatics' resources: focus on curated databases [PDF]
The SIB Swiss Institute of Bioinformatics (www.isb-sib.ch) provides world-class bioinformatics databases, software tools, services and training to the international life science community in academia and industry. These solutions allow life scientists to
Swiss Institute of Bioinformatics Members, SIB +1 more
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The DBCLS BioHackathon: standardization and interoperability for bioinformatics web services and workflows. The DBCLS BioHackathon Consortium* [PDF]
Web services have become a key technology for bioinformatics, since life science databases are globally decentralized and the exponential increase in the amount of available data demands for efficient systems without the need to transfer entire databases
Kuhn, Michael +174 more
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Bioinformatic analysis of proteomics data [PDF]
Most biochemical reactions in a cell are regulated by highly specialized proteins, which are the prime mediators of the cellular phenotype. Therefore the identification, quantitation and characterization of all proteins in a cell are of utmost importance to understand the molecular processes that mediate cellular physiology.
Andreas Schmidt 0009 +2 more
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Bi-directional gene set enrichment and canonical correlation analysis identify key diet-sensitive pathways and biomarkers of metabolic syndrome. [PDF]
peer-reviewedBackground Currently, a number of bioinformatics methods are available to generate appropriate lists of genes from a microarray experiment.
Morine Melissa J +23 more
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Data Analysis for the COVID-19 Research: Contributions of the German Network of Bioinformatics Infrastructure [PDF]
Pühler A, German Network for Bioinformatics Infrastructure (de.NBI), eds. Data Analysis for the COVID-19 Research: Contributions of the German Network of Bioinformatics Infrastructure.
German Network for Bioinformatics Infrastructure (de.NBI) +1 more
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