Results 11 to 20 of about 23,754,274 (255)

The SIB Swiss Institute of Bioinformatics' resources: focus on curated databases [PDF]

open access: yes, 2016
The SIB Swiss Institute of Bioinformatics (www.isb-sib.ch) provides world-class bioinformatics databases, software tools, services and training to the international life science community in academia and industry. These solutions allow life scientists to
Swiss Institute of Bioinformatics Members, SIB   +1 more
core   +5 more sources

SysBiolPGWAS: simplifying post-GWAS analysis through the use of computational technologies and integration of diverse omics datasets [PDF]

open access: yes, 2022
Motivation: Post-genome-wide association studies (pGWAS) analysis is designed to decipher the functional consequences of significant single-nucleotide polymorphisms (SNPs) in the era of GWAS.
Ajayi, O   +20 more
core   +1 more source

Data mining in bioinformatics using Weka [PDF]

open access: yes, 2004
The Weka machine learning workbench provides a general purpose environment for automatic classification, regression, clustering and feature selection-common data mining problems in bioinformatics research.
Ian H. Witten   +9 more
core   +2 more sources

The DBCLS BioHackathon: standardization and interoperability for bioinformatics web services and workflows [PDF]

open access: yes, 2010
Web services have become a key technology for bioinformatics, since life science databases are globally decentralized and the exponential increase in the amount of available data demands for efficient systems without the need to transfer entire databases
Kuhn, Michael   +177 more
core   +1 more source

Bioinformatics: an overview for cancer research [PDF]

open access: yes, 2012
Bioinformatics is a new science that is glowing out in the recent years. It is a multidisciplinary science that is made out of different kinds of other scientific fields like biology, computer science, chemistry, statistics, mathematics and others.
Lu, Joan, Al-Rajab, Murad
core   +2 more sources

Coordinated regulation of WNT/β-catenin, c-Met, and integrin signalling pathways by miR-193b controls triple negative breast cancer metastatic traits

open access: yesBMC Cancer, 2021
Background Triple negative breast cancer (TNBC) is the most aggressive subtype of breast cancer (BC). Treatment options for TNBC patients are limited and further insights into disease aetiology are needed to develop better therapeutic approaches ...
Chiara Giacomelli   +12 more
doaj   +1 more source

SARS-CoV-2 surveillance in Italy through phylogenomic inferences based on Hamming distances derived from pan-SNPs, -MNPs and -InDels

open access: yesBMC Genomics, 2021
Background Faced with the ongoing global pandemic of coronavirus disease, the ‘National Reference Centre for Whole Genome Sequencing of microbial pathogens: database and bioinformatic analysis’ (GENPAT) formally established at the ‘Istituto ...
Adriano Di Pasquale   +5 more
doaj   +1 more source

Harmonization of supervised machine learning practices for efficient source attribution of Listeria monocytogenes based on genomic data

open access: yesBMC Genomics, 2023
Background Genomic data-based machine learning tools are promising for real-time surveillance activities performing source attribution of foodborne bacteria such as Listeria monocytogenes.
Pierluigi Castelli   +6 more
doaj   +1 more source

Candidate methylation sites associated with endocrine therapy resistance in ER+/HER2- breast cancer

open access: yesBMC Cancer, 2020
Background Estrogen receptor (ER) positive breast cancer is often effectively treated with drugs that inhibit ER signaling, i.e., tamoxifen (TAM) and aromatase inhibitors (AIs).
Maryam Soleimani Dodaran   +6 more
doaj   +1 more source

De novo genome assembly resolving repetitive structures enables genomic analysis of 35 European Mycoplasmopsis bovis strains

open access: yesBMC Genomics, 2023
Mycoplasmopsis (M.) bovis, the agent of mastitis, pneumonia, and arthritis in cattle, harbors a small genome of approximately 1 Mbp. Combining data from Illumina and Nanopore technologies, we sequenced and assembled the genomes of 35 European strains and
Sandra Triebel   +7 more
doaj   +1 more source

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