Results 61 to 70 of about 23,754,274 (255)

The Generation Challenge Programme Platform: Semantic standards and workbench for crop science [PDF]

, 2008
The Generation Challenge programme (GCP) is a global crop research consortium directed toward crop improvement through the application of comparative biology and genetic resources characterization to plant breeding.
Peralta, Barry, Lee, Jennifer, Anacleto, Mylah, Yap, Jan Michael, Balaji, Jayashree, Manansala, Kevin, Marshall, David, Akintunde, Akinnola, Schiltz, Gary, Ruiz, M., Metz, Thomas, Valerio, Rowena, Kikuchi, Shoshi, Jaiswal, Pankaj, Ulat, Victor Jun, Hintum, T.J.L., van, Mendoza, Michael Jonathan, Wagner, James, Collins, Anthony, Martins, Natalia, Braak, Kyle, Ruiz, Manuel, Good, Benjamin, Bruskiewich, Richard, Jun Ulat, Victor, Morales, Jeffrey, Costa, Marcos, Skofic, Milko, Detras, Jeffrey, Shah, Trushar, Zhang, Yi, McLaren, Graham, Satoh, Kouji, Hazekamp, Tom, Bruskiewich, R., Simon, Reinhard, Alamban, Ryan, Farmer, Andrew, Gregorio, Sergio, Meintjes, Ayton, Davenport, G., Takeya, Masaru, Casstevens, Terry, Ritter, Sebastian, Barboza, Lord Hendrix, Rouard, M., Wanchana, Samart, Almodiel, Roque, Morris, Jane, Thongjuea, Supat, Pappas, Georgios, Senger, M., Wilkinson, Mark, Dereeper, Alexis, Rouard, Mathieu, Doi, Koji, Portugal, Arllet, Senger, Martin, Davenport, Guy, Mauleon, Ramil, Van Hintum, Theo, Mauleon, Ramil P., Rojas, Edwin, Hermocilla, Joseph, Echavez, Michael, Schiltz, G., Ritter, S., Mendoza, M.J., Alamban, R., Manansala, K., Ulat, V.J., Gregorio, S., Metz, T., Wagner, J., Kouji Satoh, Hermocilla, J., Meintjes, A., Costa, M., Skofic, M., Echavez, M., Pappas, G., Morales, J., Simon, R., Anacleto, M., McLaren, C., Farmer, A., Takeya, M., Casstevens, T., Detras, J., Barboza, L.H., Portugal, A., Jayashree, B., Yi Zhang, Mauleon, R., Wilkinson, M.D., Yap, J.M., Braak, K., Good, B., van Hintum, T., Koji Doi, Marshall, D.S., Rojas, E., Dereeper, A., Peralta, B., Lee, J., Wanchana, S., Morris, J., Almodiel,, R., Valerio, R., Martins, N., Jaiswal, P., Kikuchi, S., Akinnola Nathaniel Akintunde, Shah, T., Hazekamp, T., Collins, A.   +115 more
core   +1 more source

Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer

Molecular Oncology, EarlyView.
Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola, Yasmine Illi, Anna Bircher, Marijn Wilmink, Rachele F. Malagutti, Solenn Ottié, Cordelia Schuler, Pedro A. Ruiz, Cheryl de Vallière, Klaus Seuwen, Gerhard Rogler, Martin Hausmann   +11 more
wiley   +1 more source

RNA-protein interaction prediction without high-throughput data: An overview and benchmark of in silico tools

Computational and Structural Biotechnology Journal
RNA-protein interactions (RPIs) are crucial for accurately operating various processes in and between organisms across kingdoms of life. Mutual detection of RPI partner molecules depends on distinct sequential, structural, or thermodynamic features ...
Sarah Krautwurst, Kevin Lamkiewicz
doaj   +1 more source

Comparative transcriptomics identifies candidate genes involved in the evolutionary transition from dehiscent to indehiscent fruits in Lepidium (Brassicaceae)

BMC Plant Biology, 2022
Background Fruits are the seed-bearing structures of flowering plants and are highly diverse in terms of morphology, texture and maturation. Dehiscent fruits split open upon maturation to discharge their seeds while indehiscent fruits are dispersed as a ...
Lydia Gramzow, Katharina Klupsch, Noé Fernández-Pozo, Martin Hölzer, Manja Marz, Stefan A. Rensing, Günter Theißen   +6 more
doaj   +1 more source

Spatial and single‐nuclei transcriptomics reveals idiosyncratic and generic patterns in papillary and anaplastic thyroid cancers

Molecular Oncology, EarlyView.
Matched spatial transcriptomics and single‐nuclei RNA‐seq were generated for anaplastic and BRAFV600E papillary thyroid cancers revealing generic and tumor‐specific states occurring in cancer cells and in the tumor microenvironment. In this context, cancer dedifferentiation mirrored organoid maturation through ordered thyroid marker gain/loss ...
Adrien Tourneur, Joel Rodrigues Vitória, Manuel Saiselet, Ligia Craciun, Denis Larsimont, Anne Lefort, Frédérick Libert, Carine Maenhaut, Sabine Costagliola, Maxime Tarabichi, Mirian Romitti, Vincent Detours   +11 more
wiley   +1 more source

Flowchart of bioinformatics analysis.

, 2021
Flowchart of bioinformatics analysis.
Lihong Luo (11751849), Yilin Li (507257), Xiaowu Zhong (11594416), Qin Xiong (714473), Peimin Feng (11751855), Fengjiao Xie (11751852), Chengjiao Yao (11751846)   +6 more
core   +1 more source

Circulating microRNA signatures of cachexia and cancer in Canis familiaris as a comparative oncology model for human disease

Molecular Oncology, EarlyView.
Circulating microRNAs as biomarkers of cachexia and sex‐specific cancer in senior dogs. In 25 client‐owned dogs, four circulating miRNAs (miR‐15a, miR‐15b, miR‐16, miR‐140) were downregulated in cachexia, with miR‐16 the strongest individual biomarker (AUC = 0.899).
Soon‐Seok Park, Kyongman An, Gyeonghwa Kim, Soo‐Nyun Choi, Hong‐Ki Lee, Keun Hur, Kyu‐Shik Jeong   +6 more
wiley   +1 more source

Temporal Profiling of SARS-CoV-2 Variants Using BioEnrichPy: A Network-Based Insight into Host Disruption and Neurodegeneration

COVID
SARS-CoV-2, the virus responsible for COVID-19, disrupts human cellular pathways through complex protein–protein interaction, contributing to disease progression. As the virus has evolved, emerging variants have exhibited differences in transmissibility,
Sreelakshmi Kalayakkattil, Ananthakrishnan Anil Indu, Punya Sunil, Haritha Nekkanti, Smitha Shet, Ranajit Das   +5 more
doaj   +1 more source

Unraveling mitotic protein networks by 3D multiplexed epitope drug screening

Molecular Systems Biology, 2018
Three‐dimensional protein localization intricately determines the functional coordination of cellular processes. The complex spatial context of protein landscape has been assessed by multiplexed immunofluorescent staining or mass spectrometry, applied to
Lorenz J Maier, Stefan M Kallenberger, Katharina Jechow, Marcel Waschow, Roland Eils, Christian Conrad   +5 more
doaj   +1 more source

CEACAM1 participation in breast cancer progression

Molecular Oncology, EarlyView.
In invasive breast cancer (BC), CEACAM1 shifts from an apical to a uniform membranous/cytoplasmic pattern, or is lost, as tumors dedifferentiate, inversely tracking the Ki‐67 proliferative index. In MCF‐7 cells, only CEACAM1‐4L suppresses proliferation, repressing cell cycle and growth factor genes.
Mykola Lyndin, Irina Kube‐Golovin, Anatolii Romaniuk, Gunther Wennemuth   +3 more
wiley   +1 more source