Results 81 to 90 of about 640,321 (318)
Computational and Structural Biotechnology JournalRNA-protein interactions (RPIs) are crucial for accurately operating various processes in and between organisms across kingdoms of life. Mutual detection of RPI partner molecules depends on distinct sequential, structural, or thermodynamic features ...
Sarah Krautwurst, Kevin Lamkiewicz
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BMC Plant Biology, 2022 Background Fruits are the seed-bearing structures of flowering plants and are highly diverse in terms of morphology, texture and maturation. Dehiscent fruits split open upon maturation to discharge their seeds while indehiscent fruits are dispersed as a ...
Lydia Gramzow +6 more
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Seasonality of endemic COVID-19
mBio, 2023 Successive waves of infection by SARS-CoV-2 have left little doubt that this virus will transition to an endemic disease. Foreknowledge of when to expect seasonal surges is crucial for healthcare and public health decision-making.
Jeffrey P. Townsend +8 more
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Molecular Oncology, EarlyView.In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge +17 more
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Globaltest and GOEAST: two different approaches for Gene Ontology analysis [PDF]
, 2009 Background Gene set analysis is a commonly used method for analysing microarray data by considering groups of functionally related genes instead of individual genes.
Kommadath, A. +5 more
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Molecular Oncology, EarlyView.Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau +36 more
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SOBA: sequence ontology bioinformatics analysis [PDF]
Nucleic Acids Research, 2010 The advent of cheaper, faster sequencing technologies has pushed the task of sequence annotation from the exclusive domain of large-scale multi-national sequencing projects to that of research laboratories and small consortia. The bioinformatics burden placed on these laboratories, some with very little programming experience can be daunting ...
Barry Moore, Guozhen Fan, Karen Eilbeck
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Development of system for analysis and prediction of function for DNA sequences [PDF]
, 2009 [[abstract]]After the completion of human genome project, Arabidopsis , rice and other species, genome researchers are shifting their research attentions from structural genomics to functional genomics.
Han-Wei Wu
core
COVIDSARS-CoV-2, the virus responsible for COVID-19, disrupts human cellular pathways through complex protein–protein interaction, contributing to disease progression. As the virus has evolved, emerging variants have exhibited differences in transmissibility,
Sreelakshmi Kalayakkattil +5 more
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Unraveling mitotic protein networks by 3D multiplexed epitope drug screening
Molecular Systems Biology, 2018 Three‐dimensional protein localization intricately determines the functional coordination of cellular processes. The complex spatial context of protein landscape has been assessed by multiplexed immunofluorescent staining or mass spectrometry, applied to
Lorenz J Maier +5 more
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