Results 41 to 50 of about 10,923,960 (347)

Bioinformatic analysis of potential hub genes in gastric adenocarcinoma [PDF]

open access: yesScience Progress, 2021
Gastric adenocarcinoma is the most common histologic type of gastric cancer; however, the pathogenic mechanisms remain unclear. To improve mechanistic understanding and identify new treatment targets or diagnostic biomarkers, we used bioinformatic tools to predict the hub genes related to the process of gastric adenocarcinoma development from public ...
Hao Liu   +5 more
openaire   +2 more sources

Nuclear speckles: dynamic hubs of gene expression regulation [PDF]

open access: yesThe FEBS Journal, 2021
Complex, multistep biochemical reactions that routinely take place in our cells require high concentrations of enzymes, substrates, and other structural components to proceed efficiently and typically require chemical environments that can inhibit other reactions in their immediate vicinity.
İbrahim Avşar Ilık, Tuğçe Aktaş
openaire   +3 more sources

united-manufacturing-hub/united-manufacturing-hub: v0.9.16

open access: yes, 2023
<h2>What's Changed</h2> <ul> <li>fix: changed links from docker to GHCR by @Vermuden in https://github.com/united-manufacturing-hub/united-manufacturing-hub/pull/1532</li> <li>build(deps): bump golang.org/x/crypto from
kruegeralex   +20 more
core   +2 more sources

The nuclear lamina as a gene-silencing hub. [PDF]

open access: yesCurrent issues in molecular biology, 2012
There is accumulating evidence that the nuclear periphery is a transcriptionally repressive compartment. A surprisingly large fraction of the genome is either in transient or permanent contact with nuclear envelope, where the majority of genes are maintained in a silent state, waiting to be awakened during cell differentiation.
Yuri Y, Shevelyov, Dmitry I, Nurminsky
openaire   +3 more sources

Identification of Hub Genes and MicroRNAs Associated With Idiopathic Pulmonary Arterial Hypertension by Integrated Bioinformatics Analyses

open access: yesFrontiers in Genetics, 2021
ObjectiveThe aim of this study is the identification of hub genes associated with idiopathic pulmonary arterial hypertension (IPAH).Materials and MethodsGSE15197 gene expression data was downloaded from the Gene Expression Omnibus (GEO) database ...
Xue Qiu   +5 more
doaj   +1 more source

Exploration and validation of related hub gene expression during SARS-CoV-2 infection of human bronchial organoids

open access: yesHuman Genomics, 2021
Background In the novel coronavirus pandemic, the high infection rate and high mortality have seriously affected people’s health and social order. To better explore the infection mechanism and treatment, the three-dimensional structure of human bronchus ...
Ke-ying Fang   +8 more
semanticscholar   +1 more source

The Core Promoter Is a Regulatory Hub for Developmental Gene Expression [PDF]

open access: yesFrontiers in Cell and Developmental Biology, 2021
The development of multicellular organisms and the uniqueness of each cell are achieved by distinct transcriptional programs. Multiple processes that regulate gene expression converge at the core promoter region, an 80 bp region that directs accurate transcription initiation by RNA polymerase II (Pol II).
Anna Sloutskin   +3 more
openaire   +3 more sources

The environmental cost implication of hub-hub versus hub bypass flight networks [PDF]

open access: yes, 2007
The increasing congestion at major hubs and the advantage to passengers of non-stop flights and faster journey times has intensified the debate on patterns of air service.
Morrell, Peter, Lu, Cherie
core   +1 more source

united-manufacturing-hub/united-manufacturing-hub: 0.9.6 post release tag

open access: yes, 2022
Tldr ⚠⚠⚠ ⚠⚠⚠ this is a test regarding permissions, please disregard this release for any kind of productive use ⚠⚠⚠ What's Changed build(deps): bump github.com/minio/minio-go/v7 from 7.0.29 to 7.0.34 in /golang by @dependabot in https://github.com ...
kruegeralex   +17 more
core   +1 more source

Identification of the Real Hub Gene and Construction of a Novel Prognostic Signature for Pancreatic Adenocarcinoma Based on the Weighted Gene Co-expression Network Analysis and Least Absolute Shrinkage and Selection Operator Algorithms

open access: yesFrontiers in Genetics, 2021
Background: Pancreatic adenocarcinoma (PAAD) has a considerably bad prognosis, and its pathophysiologic mechanism remains unclear. Thus, we aimed to identify real hub genes to better explore the pathophysiology of PAAD and construct a prognostic panel to
Q. Yuan   +5 more
semanticscholar   +1 more source

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