Results 1 to 10 of about 577,457 (165)

Hunting for differentially expressed genes [PDF]

open access: yesBrazilian Journal of Medical and Biological Research, 1999
Differentially expressed genes are usually identified by comparing steady-state mRNA concentrations. Several methods have been used for this purpose, including differential hybridization, cDNA subtraction, differential display and, more recently, DNA ...
C.G. Vedoy, M.H. Bengtson, M.C. Sogayar
doaj   +5 more sources

Detecting multivariate differentially expressed genes [PDF]

open access: yesBMC Bioinformatics, 2007
Background Gene expression is governed by complex networks, and differences in expression patterns between distinct biological conditions may therefore be complex and multivariate in nature.
Tegnér Jesper   +3 more
doaj   +3 more sources

Evaluation of Combining Several Statistical Methods with a Flexible Cutoff for Identifying Differentially Expressed Genes in Pairwise Comparison of EST Sets

open access: yesBioinformatics and Biology Insights, 2008
The detection of differentially expressed genes from EST data is of importance for the discovery of potential biological or pharmaceutical targets, especially when studying biological processes in less characterized organisms and where large-scale ...
Angelica Lindlöf   +4 more
doaj   +2 more sources

Potential biomarkers and molecular mechanisms in preeclampsia progression

open access: yesOpen Life Sciences, 2022
This study aimed to explore potential biomarkers and molecular mechanisms in preeclampsia (PE) progression. Gene expression profiles of GSE147776 and GSE96984 were downloaded, followed by the identification of common differentially expressed genes (co ...
Li Guohua   +3 more
doaj   +1 more source

Differential gene expression in mesothelioma [PDF]

open access: yesFEBS Letters, 2000
To investigate the molecular events controlling malignant transformation of human pleural cells, we compared constitutive gene expression of mesothelioma cells to that of pleural cells. Using cDNA microarray and high‐density filter array, we assessed expression levels of >6500 genes.
Rihn, B.H.   +7 more
openaire   +2 more sources

Identification of the transcriptome profile of after mebendazole treatment [PDF]

open access: yesKosin Medical Journal, 2022
Background The scuticociliate Miamiensis avidus is a major pathogenic agent that causes significant economic losses in the flounder aquaculture industry. Many different types of drugs are being tested to control this disease, including mebendazole, which
Hyunsu Kim   +5 more
doaj   +1 more source

GENE EXPRESSION IN DIFFERENTIATED CELLS [PDF]

open access: yesProceedings of the National Academy of Sciences, 1963
This communication is concerned with the dynamics of gene control over specific biochemical functions in a differentiated cell. Direct experimental access to the intracellular link between gene action and the target cell characters has become feasible with the accumulation of evidence demonstrating that the synthesis of specific RNA's on the genomic ...
Davidson, E. H.   +2 more
openaire   +4 more sources

Uncovering potential genes in colorectal cancer based on integrated and DNA methylation analysis in the gene expression omnibus database

open access: yesBMC Cancer, 2022
Background Colorectal cancer (CRC) is major cancer-related death. The aim of this study was to identify differentially expressed and differentially methylated genes, contributing to explore the molecular mechanism of CRC.
Guanglin Wang   +8 more
doaj   +1 more source

Transcriptomic and proteomic analyses of ovarian follicles reveal the role of VLDLR in chicken follicle selection

open access: yesBMC Genomics, 2020
Background Follicle selection in chickens refers to the process of selecting one follicle from a group of small yellow follicles (SY, 6–8 mm in diameter) for development into 12–15 mm hierarchical follicles (usually F6 follicles), which is an important ...
Qiuyue Chen   +6 more
doaj   +1 more source

Bioinformatics analysis of miRNA and mRNA expression profiles to reveal the key miRNAs and genes in osteoarthritis

open access: yesJournal of Orthopaedic Surgery and Research, 2021
Background Osteoarthritis (OA) is a chronic degenerative joint disease and the most frequent type of arthritis. This study aimed to identify the key miRNAs and genes associated with OA progression.
Pei-yan Huang   +6 more
doaj   +1 more source

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