Results 31 to 40 of about 678,844 (309)

Identification of key genes and miRNAs related to polycystic ovary syndrome by comprehensive analysis of microarray

BMC Medical Genomics, 2022
Background We aimed to explore mechanisms of development and progression of polycystic ovary syndrome (PCOS). Methods The microRNA expression microarray GSE37914 and gene expression profiles GSE43264 and GSE98421 were downloaded from the Gene Expression ...
Ziqian Sun, Yang Wang, Tianshu Wei, Li Liu   +3 more
doaj   +1 more source

Data-driven detection of subtype-specific differentially expressed genes

Scientific Reports, 2021
Among multiple subtypes of tissue or cell, subtype-specific differentially-expressed genes (SDEGs) are defined as being most-upregulated in only one subtype but not in any other. Detecting SDEGs plays a critical role in the molecular characterization and
Lulu Chen, Yingzhou Lu, Chiung-Ting Wu, Robert Clarke, Guoqiang Yu, Jennifer E. Van Eyk, David M. Herrington, Yue Wang   +7 more
doaj   +1 more source

Differentially expressed genes.

, 2022
Fold change of differentially expressed genes commonly annotated in combination treated cells. (PDF)
Helen Heyerdahl (312672), Marion M. Malenge (12481295), Jostein Dahle (312685), Sebastian Patzke (753506), Arne Kolstad (765765), Trond Stokke (66426), Astri Fjelde Maaland (8595453), Lydia Visser (151980), Anne Hansen Ree (8621367), Brian Middleton (2053249), Ada Repetto-Llamazares (12481298), Marcel Nijland (844725)   +11 more
core   +2 more sources

Potential biomarkers that discriminate rheumatoid arthritis and osteoarthritis based on the analysis and validation of datasets

BMC Musculoskeletal Disorders, 2022
Background Rheumatoid arthritis (RA) and osteoarthritis (OA) share some similar arthritic symptoms, but different mechanisms underlie the pathogenesis of these two diseases.
Le Kang, Chengqian Dai, Lihong Wang, Xinling Pan   +3 more
doaj   +1 more source

Comparative expression profiling of Leishmania: modulation in gene expression between species and in different host genetic backgrounds. [PDF]

, 2009
Genome sequencing of Leishmania species that give rise to a range of disease phenotypes in the host has revealed highly conserved gene content and synteny across the genus.
Alasdair C Ivens, Ivens, Alasdair C, Maroof, Asher, Paul M Kaye, Depledge Daniel P., Depledge, DP, Ivens, AC, Depledge, Daniel P, Maroof Asher, Aziz Naveed, Evans, KJ, Smith, Deborah F, Kaye, PM, Maroof, A, Smith, DF, Aziz, Naveed, Daniel P Depledge, Naveed Aziz, Ivens Alasdair C., Asher Maroof, Krystal J Evans, Evans Krystal J., Kaye Paul M., Aziz, N, Evans, Krystal J, Smith Deborah F., Kaye, Paul M, Deborah F Smith   +27 more
core   +1 more source

Exploring the Pathogenesis of Psoriasis Complicated With Atherosclerosis via Microarray Data Analysis

Frontiers in Immunology, 2021
BackgroundAlthough more and more evidence has supported psoriasis is prone to atherosclerosis, the common mechanism of its occurrence is still not fully elucidated. The purpose of this study is to further explore the molecular mechanism of the occurrence
Wenxing Su, Wenxing Su, Ying Zhao, Yuqian Wei, Xiaoyan Zhang, Jiang Ji, Shun Yang   +6 more
doaj   +1 more source

Differential Gene Expression in Glaucoma [PDF]

Cold Spring Harbor Perspectives in Medicine, 2014
In glaucoma, regardless of its etiology, retinal ganglion cells degenerate and eventually die. Although age and elevated intraocular pressure (IOP) are the main risk factors, there are still many mysteries in the pathogenesis of glaucoma. The advent of genome-wide microarray expression screening together with the availability of animal models of the ...
openaire   +2 more sources

Differential expression of the p65 gene family [PDF]

Neuron, 1991
The genome of the marine ray Discopyge ommata contains at least three p65-related genes. o-p65-A is 84% identical, o-p65-B is 78% identical, and o-p65-C is only 41% identical to a previously characterized rat p65. The cytoplasmic domain, particularly the two regions that are similar to the regulatory domain of protein kinase C, are most highly ...
B, Wendland, K G, Miller, J, Schilling, R H, Scheller   +3 more
openaire   +2 more sources

Comparative transcriptome analysis of two selenium-accumulating genotypes of Aegilops tauschii Coss. in response to selenium

BMC Genetics, 2019
Background Selenium (Se), an essential micronutrient in both animals and humans, has various biological functions, and its deficiency can lead to various diseases.
Lijun Wu, Tao Liu, Yongsheng Xu, Wenjie Chen, Baolong Liu, Lianquan Zhang, Dengcai Liu, Huaigang Zhang, Bo Zhang   +8 more
doaj   +1 more source

Predictability of human differential gene expression [PDF]

Proceedings of the National Academy of Sciences, 2019
Differential expression (DE) is commonly used to explore molecular mechanisms of biological conditions. While many studies report significant results between their groups of interest, the degree to which results are specific to the question at hand is not generally assessed, potentially leading to inaccurate interpretation.
Crow, M, Lim, N, Ballouz, S, Pavlidis, P, Gillis, J   +4 more
openaire   +3 more sources