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Differential Gene Expression and Aging [PDF]

The Scientific World JOURNAL, 2002
It has been established that an intricate program of gene expression controls progression through the different stages in development. The equally complex biological phenomenon known as aging is genetically determined and environmentally modulated.
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Differential Gene Expression in Glaucoma [PDF]

Cold Spring Harbor Perspectives in Medicine, 2014
In glaucoma, regardless of its etiology, retinal ganglion cells degenerate and eventually die. Although age and elevated intraocular pressure (IOP) are the main risk factors, there are still many mysteries in the pathogenesis of glaucoma. The advent of genome-wide microarray expression screening together with the availability of animal models of the ...
openaire   +2 more sources

Heatmaps as for expression and methyaltion of validated-Differentially-Expressed-Genes-Differentially-Methylated-Genes (vDEGs-DMGs) based on our participants’ data.

, 2022
The top left corner) Expression values of over-expressed/hypo-methylated vDEGs-DMGs. The bottom left corner) Expression values of under-expressed/hyper-methylated vDEGs-DMGs.
Amir Mehrgou (12295124), Shahram Teimourian (12295127)   +1 more
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Metabolomic and transcriptomic analyses of mutant yellow leaves provide insights into pigment synthesis and metabolism in Ginkgo biloba

BMC Genomics, 2020
Background Ginkgo (Ginkgo biloba L.) is an excellent landscape species. Its yellow-green leaf mutants are ideal materials for research on pigment synthesis, but the regulatory mechanism of leaf coloration in these ginkgo mutants remains unclear.
Yaqiong Wu, Jing Guo, Tongli Wang, Fuliang Cao, Guibin Wang   +4 more
doaj   +1 more source

Potential biomarkers that discriminate rheumatoid arthritis and osteoarthritis based on the analysis and validation of datasets

BMC Musculoskeletal Disorders, 2022
Background Rheumatoid arthritis (RA) and osteoarthritis (OA) share some similar arthritic symptoms, but different mechanisms underlie the pathogenesis of these two diseases.
Le Kang, Chengqian Dai, Lihong Wang, Xinling Pan   +3 more
doaj   +1 more source

Identification of Differentially Up-regulated Genes in Apple with White Rot Disease

The Plant Pathology Journal, 2019
Fuji, a major apple cultivar in Korea, is susceptible to white rot. Apple white rot disease appears on the stem and fruit; the development of which deteriorates fruit quality, resulting in decreases in farmers' income.
Yeo-Jin Kang, Young Koung Lee, In-Jung Kim   +2 more
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Exploring the Pathogenesis of Psoriasis Complicated With Atherosclerosis via Microarray Data Analysis

Frontiers in Immunology, 2021
BackgroundAlthough more and more evidence has supported psoriasis is prone to atherosclerosis, the common mechanism of its occurrence is still not fully elucidated. The purpose of this study is to further explore the molecular mechanism of the occurrence
Wenxing Su, Wenxing Su, Ying Zhao, Yuqian Wei, Xiaoyan Zhang, Jiang Ji, Shun Yang   +6 more
doaj   +1 more source

Differential expression of the p65 gene family [PDF]

Neuron, 1991
The genome of the marine ray Discopyge ommata contains at least three p65-related genes. o-p65-A is 84% identical, o-p65-B is 78% identical, and o-p65-C is only 41% identical to a previously characterized rat p65. The cytoplasmic domain, particularly the two regions that are similar to the regulatory domain of protein kinase C, are most highly ...
B, Wendland, K G, Miller, J, Schilling, R H, Scheller   +3 more
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Identification of hub genes in rheumatoid arthritis through an integrated bioinformatics approach

Journal of Orthopaedic Surgery and Research, 2021
Background Rheumatoid arthritis (RA) is a common chronic autoimmune disease characterized by inflammation of the synovial membrane. However, the etiology and underlying molecular events of RA are unclear.
Rui Wu, Li Long, Qiao Zhou, Jiang Su, Wei Su, Jing Zhu   +5 more
doaj   +1 more source

Comparative expression profiling of Leishmania: modulation in gene expression between species and in different host genetic backgrounds. [PDF]

, 2009
Genome sequencing of Leishmania species that give rise to a range of disease phenotypes in the host has revealed highly conserved gene content and synteny across the genus.
Alasdair C Ivens, Ivens, Alasdair C, Maroof, Asher, Paul M Kaye, Depledge Daniel P., Depledge, DP, Ivens, AC, Depledge, Daniel P, Maroof Asher, Aziz Naveed, Evans, KJ, Smith, Deborah F, Kaye, PM, Maroof, A, Smith, DF, Aziz, Naveed, Daniel P Depledge, Naveed Aziz, Ivens Alasdair C., Asher Maroof, Krystal J Evans, Evans Krystal J., Kaye Paul M., Aziz, N, Evans, Krystal J, Smith Deborah F., Kaye, Paul M, Deborah F Smith   +27 more
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