Results 21 to 30 of about 3,651,834 (302)
Informatics in Medicine Unlocked, 2021 Gastric cancer (GC) is the third cause of cancer mortality in the world but the molecular mechanisms underlying the pathogenesis of GC remain little known.
Homa Akhavan +3 more
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MODELING GENE EXPRESSION WITH DIFFERENTIAL EQUATIONS [PDF]
Biocomputing '99, 1998 We propose a differential equation model for gene expression and provide two methods to construct the model from a set of temporal data. We model both transcription and translation by kinetic equations with feedback loops from translation products to transcription. Degradation of proteins and mRNAs is also incorporated.
Ting Chen +2 more
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Bioinformatics analysis: A roadmap to an aggressiveness model for Oral Squamous cell carcinoma key differentiated genes [PDF]
Alexandria Dental JournalIntroductionBioinformatics is a cross-disciplinary research field that combines computer science with biological science. The most fundamental yet frequently most impactful application of bioinformatics analysis is identifying variations in gene ...
Heba Mady +4 more
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Hybridization and gene expression: Beyond differentially expressed genes [PDF]
Molecular EcologyAbstractGene expression has a key role in reproductive isolation, and studies of hybrid gene expression have identified mechanisms causing hybrid sterility. Here, we review the evidence for altered gene expression following hybridization and outline the mechanisms shown to contribute to altered gene expression in hybrids. Transgressive gene expression,
Runemark, Anna +2 more
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Bayesian Modeling of Differential Gene Expression [PDF]
Biometrics, 2005 Summary We present a Bayesian hierarchical model for detecting differentially expressing genes that includes simultaneous estimation of array effects, and show how to use the output for choosing lists of genes for further investigation. We give empirical evidence that expression‐level dependent array effects are needed, and explore different nonlinear ...
Lewin, Alex +4 more
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Identification of Key Genes Between Lung Adenocarcinoma and Lung Squamous Cell Carcinoma by Bioinformatics Analysis [PDF]
Advanced Ultrasound in Diagnosis and Therapy, 2020 Objective: To explore differentially expressed genes (DEGs) between lung adenocarcinoma (LUAD) and lung squamous cell carcinoma (LUSC).Methods: Based on GEO database, we used R software to identify the DEGs and conducted the bioinformatics analysis to ...
Jinru Xue, MS, Yu Yang, MS, Bo Jiang, MD, Linxue Qian, MD, Xian-Quan Shi, PhD
doaj +1 more source
Differential Cellular Gene Expression in Ganglioglioma [PDF]
Epilepsia, 2007 Summary: Purpose: Gangliogliomas (GGs) are neuronal‐glial tumors highly associated with epilepsy. We hypothesized that the expression of select gene families including neurotransmitter receptor subunits and growth factors would be distinct in neurons and astrocytes within GG compared with adjacent cortex and that these changes would yield insights into
Samadani, Uzma +4 more
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BMC Medical Genomics, 2022 Background We aimed to explore mechanisms of development and progression of polycystic ovary syndrome (PCOS). Methods The microRNA expression microarray GSE37914 and gene expression profiles GSE43264 and GSE98421 were downloaded from the Gene Expression ...
Ziqian Sun +3 more
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Differentially-expressed genes (DEGs) detected at FDR < 0.05.
, 2023 Differentially-expressed genes (DEGs) detected at FDR < 0.05.
Daniel M. Kerr (9745666) +7 more
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Data-driven detection of subtype-specific differentially expressed genes
Scientific Reports, 2021 Among multiple subtypes of tissue or cell, subtype-specific differentially-expressed genes (SDEGs) are defined as being most-upregulated in only one subtype but not in any other. Detecting SDEGs plays a critical role in the molecular characterization and
Lulu Chen +7 more
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