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Heatmaps as for expression and methyaltion of validated-Differentially-Expressed-Genes-Differentially-Methylated-Genes (vDEGs-DMGs) based on our participants’ data.

, 2022
The top left corner) Expression values of over-expressed/hypo-methylated vDEGs-DMGs. The bottom left corner) Expression values of under-expressed/hyper-methylated vDEGs-DMGs.
Amir Mehrgou (12295124), Shahram Teimourian (12295127)   +1 more
core   +1 more source

Hybridization and gene expression: Beyond differentially expressed genes [PDF]

Molecular Ecology
AbstractGene expression has a key role in reproductive isolation, and studies of hybrid gene expression have identified mechanisms causing hybrid sterility. Here, we review the evidence for altered gene expression following hybridization and outline the mechanisms shown to contribute to altered gene expression in hybrids. Transgressive gene expression,
Runemark, Anna, Moore, Emily C., Larson, Erica L.   +2 more
openaire   +2 more sources

MODELING GENE EXPRESSION WITH DIFFERENTIAL EQUATIONS [PDF]

Biocomputing '99, 1998
We propose a differential equation model for gene expression and provide two methods to construct the model from a set of temporal data. We model both transcription and translation by kinetic equations with feedback loops from translation products to transcription. Degradation of proteins and mRNAs is also incorporated.
Ting Chen, Hongyu L. He, George M. Church   +2 more
openaire   +3 more sources

Bioinformatics analysis: A roadmap to an aggressiveness model for Oral Squamous cell carcinoma key differentiated genes [PDF]

Alexandria Dental Journal
IntroductionBioinformatics is a cross-disciplinary research field that combines computer science with biological science. The most fundamental yet frequently most impactful application of bioinformatics analysis is identifying variations in gene ...
Heba Mady, Nefertiti Elnikhely, Samar El Achy, Enas Omar, Omneya Ramadan   +4 more
doaj   +1 more source

Identification of Key Genes Between Lung Adenocarcinoma and Lung Squamous Cell Carcinoma by Bioinformatics Analysis [PDF]

Advanced Ultrasound in Diagnosis and Therapy, 2020
Objective: To explore differentially expressed genes (DEGs) between lung adenocarcinoma (LUAD) and lung squamous cell carcinoma (LUSC).Methods: Based on GEO database, we used R software to identify the DEGs and conducted the bioinformatics analysis to ...
Jinru Xue, MS, Yu Yang, MS, Bo Jiang, MD, Linxue Qian, MD, Xian-Quan Shi, PhD
doaj   +1 more source

Bayesian Modeling of Differential Gene Expression [PDF]

Biometrics, 2005
Summary We present a Bayesian hierarchical model for detecting differentially expressing genes that includes simultaneous estimation of array effects, and show how to use the output for choosing lists of genes for further investigation. We give empirical evidence that expression‐level dependent array effects are needed, and explore different nonlinear ...
Lewin, Alex, Richardson, Sylvia, Marshall, Clare, Glazier, Anne, Aitman, Tim   +4 more
openaire   +2 more sources

Iterative Group Analysis (iGA): A simple tool to enhance sensitivity and facilitate interpretation of microarray experiments [PDF]

, 2004
BACKGROUND: The biological interpretation of even a simple microarray experiment can be a challenging and highly complex task. Here we present a new method (Iterative Group Analysis) to facilitate, improve, and accelerate this process.
Amtmann, A., Herzyk, P., Anna Amtmann, Amtmann, Anna, Herzyk, Pawel, Breitling, Rainer, Breitling, R., Rainer Breitling, Pawel Herzyk   +8 more
core   +1 more source

Differential Cellular Gene Expression in Ganglioglioma [PDF]

Epilepsia, 2007
Summary: Purpose: Gangliogliomas (GGs) are neuronal‐glial tumors highly associated with epilepsy. We hypothesized that the expression of select gene families including neurotransmitter receptor subunits and growth factors would be distinct in neurons and astrocytes within GG compared with adjacent cortex and that these changes would yield insights into
Samadani, Uzma, Judkins, Alexander R., Akpalu, Albert, Aronica, Eleonora, Crino, Peter B.   +4 more
openaire   +2 more sources

Differential Gene Expression and Aging [PDF]

The Scientific World JOURNAL, 2002
It has been established that an intricate program of gene expression controls progression through the different stages in development. The equally complex biological phenomenon known as aging is genetically determined and environmentally modulated.
openaire   +3 more sources

Metabolomic and transcriptomic analyses of mutant yellow leaves provide insights into pigment synthesis and metabolism in Ginkgo biloba

BMC Genomics, 2020
Background Ginkgo (Ginkgo biloba L.) is an excellent landscape species. Its yellow-green leaf mutants are ideal materials for research on pigment synthesis, but the regulatory mechanism of leaf coloration in these ginkgo mutants remains unclear.
Yaqiong Wu, Jing Guo, Tongli Wang, Fuliang Cao, Guibin Wang   +4 more
doaj   +1 more source