Results 21 to 30 of about 925,682 (298)

Data-driven detection of subtype-specific differentially expressed genes

open access: yesScientific Reports, 2021
Among multiple subtypes of tissue or cell, subtype-specific differentially-expressed genes (SDEGs) are defined as being most-upregulated in only one subtype but not in any other. Detecting SDEGs plays a critical role in the molecular characterization and
Lulu Chen   +7 more
doaj   +1 more source

Transcription analysis of apple fruit development using cDNA microarrays [PDF]

open access: yes, 2009
The knowledge of the molecular mechanisms underlying fruit quality traits is fundamental to devise efficient marker-assisted selection strategies and to improve apple breeding.
Costa, F.   +5 more
core   +3 more sources

Bayesian Modeling of Differential Gene Expression [PDF]

open access: yesBiometrics, 2005
Summary We present a Bayesian hierarchical model for detecting differentially expressing genes that includes simultaneous estimation of array effects, and show how to use the output for choosing lists of genes for further investigation. We give empirical evidence that expression‐level dependent array effects are needed, and explore different nonlinear ...
Lewin, Alex   +4 more
openaire   +2 more sources

Predictive analysis of microarray data [PDF]

open access: yes, 2014
Microarray gene expression data are analyzed by means of a Bayesian nonparametric model, with emphasis on prediction of future observables, yielding a method for selection of differentially expressed genes and a ...
F., Paulo C. Marques   +1 more
core   +1 more source

Pomelo II: finding differentially expressed genes [PDF]

open access: yesNucleic Acids Research, 2009
Pomelo II (http://pomelo2.bioinfo.cnio.es) is an open-source, web-based, freely available tool for the analysis of gene (and protein) expression and tissue array data. Pomelo II implements: permutation-based tests for class comparisons (t-test, ANOVA) and regression; survival analysis using Cox model; contingency table analysis with Fisher's exact test;
Morrissey, Edward R.   +1 more
openaire   +3 more sources

Metabolomic and transcriptomic analyses of mutant yellow leaves provide insights into pigment synthesis and metabolism in Ginkgo biloba

open access: yesBMC Genomics, 2020
Background Ginkgo (Ginkgo biloba L.) is an excellent landscape species. Its yellow-green leaf mutants are ideal materials for research on pigment synthesis, but the regulatory mechanism of leaf coloration in these ginkgo mutants remains unclear.
Yaqiong Wu   +4 more
doaj   +1 more source

Computational search for UV radiation resistance strategies in Deinococcus swuensis isolated from Paramo ecosystems [PDF]

open access: yes, 2019
Ultraviolet radiation (UVR) is widely known as deleterious for many organisms since it can cause damage to biomolecules either directly or indirectly via the formation of reactive oxygen species. The goal of this study was to analyze the capacity of high-
Acosta, Iván Camilo   +6 more
core   +2 more sources

Differential Cellular Gene Expression in Ganglioglioma [PDF]

open access: yesEpilepsia, 2007
Summary: Purpose: Gangliogliomas (GGs) are neuronal‐glial tumors highly associated with epilepsy. We hypothesized that the expression of select gene families including neurotransmitter receptor subunits and growth factors would be distinct in neurons and astrocytes within GG compared with adjacent cortex and that these changes would yield insights into
Samadani, Uzma   +4 more
openaire   +2 more sources

Identification of key genes and miRNAs related to polycystic ovary syndrome by comprehensive analysis of microarray

open access: yesBMC Medical Genomics, 2022
Background We aimed to explore mechanisms of development and progression of polycystic ovary syndrome (PCOS). Methods The microRNA expression microarray GSE37914 and gene expression profiles GSE43264 and GSE98421 were downloaded from the Gene Expression ...
Ziqian Sun   +3 more
doaj   +1 more source

Gene transcription analysis during interaction between potato and Ralstonia solanacearum [PDF]

open access: yes, 2010
Bacterial wilt (BW) caused by Ralstonia solanacearum (Rs) is an important quarantine disease that spreads worldwide and infects hundreds of plant species. The BW defense response of potato is a complicated continuous process, which involves transcription
Huang, S.W.   +7 more
core   +2 more sources

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