Results 21 to 30 of about 579,154 (265)

Differential Cellular Gene Expression in Ganglioglioma [PDF]

open access: yesEpilepsia, 2007
Summary: Purpose: Gangliogliomas (GGs) are neuronal‐glial tumors highly associated with epilepsy. We hypothesized that the expression of select gene families including neurotransmitter receptor subunits and growth factors would be distinct in neurons and astrocytes within GG compared with adjacent cortex and that these changes would yield insights into
Samadani, Uzma   +4 more
openaire   +2 more sources

Differential Gene Expression and Aging [PDF]

open access: yesThe Scientific World JOURNAL, 2002
It has been established that an intricate program of gene expression controls progression through the different stages in development. The equally complex biological phenomenon known as aging is genetically determined and environmentally modulated.
openaire   +3 more sources

Identification of key genes and miRNAs related to polycystic ovary syndrome by comprehensive analysis of microarray

open access: yesBMC Medical Genomics, 2022
Background We aimed to explore mechanisms of development and progression of polycystic ovary syndrome (PCOS). Methods The microRNA expression microarray GSE37914 and gene expression profiles GSE43264 and GSE98421 were downloaded from the Gene Expression ...
Ziqian Sun   +3 more
doaj   +1 more source

Data-driven detection of subtype-specific differentially expressed genes

open access: yesScientific Reports, 2021
Among multiple subtypes of tissue or cell, subtype-specific differentially-expressed genes (SDEGs) are defined as being most-upregulated in only one subtype but not in any other. Detecting SDEGs plays a critical role in the molecular characterization and
Lulu Chen   +7 more
doaj   +1 more source

Metabolomic and transcriptomic analyses of mutant yellow leaves provide insights into pigment synthesis and metabolism in Ginkgo biloba

open access: yesBMC Genomics, 2020
Background Ginkgo (Ginkgo biloba L.) is an excellent landscape species. Its yellow-green leaf mutants are ideal materials for research on pigment synthesis, but the regulatory mechanism of leaf coloration in these ginkgo mutants remains unclear.
Yaqiong Wu   +4 more
doaj   +1 more source

Potential biomarkers that discriminate rheumatoid arthritis and osteoarthritis based on the analysis and validation of datasets

open access: yesBMC Musculoskeletal Disorders, 2022
Background Rheumatoid arthritis (RA) and osteoarthritis (OA) share some similar arthritic symptoms, but different mechanisms underlie the pathogenesis of these two diseases.
Le Kang   +3 more
doaj   +1 more source

Exploring the Pathogenesis of Psoriasis Complicated With Atherosclerosis via Microarray Data Analysis

open access: yesFrontiers in Immunology, 2021
BackgroundAlthough more and more evidence has supported psoriasis is prone to atherosclerosis, the common mechanism of its occurrence is still not fully elucidated. The purpose of this study is to further explore the molecular mechanism of the occurrence
Wenxing Su   +6 more
doaj   +1 more source

Differential Gene Expression in Glaucoma [PDF]

open access: yesCold Spring Harbor Perspectives in Medicine, 2014
In glaucoma, regardless of its etiology, retinal ganglion cells degenerate and eventually die. Although age and elevated intraocular pressure (IOP) are the main risk factors, there are still many mysteries in the pathogenesis of glaucoma. The advent of genome-wide microarray expression screening together with the availability of animal models of the ...
openaire   +2 more sources

Identification of Differentially Up-regulated Genes in Apple with White Rot Disease

open access: yesThe Plant Pathology Journal, 2019
Fuji, a major apple cultivar in Korea, is susceptible to white rot. Apple white rot disease appears on the stem and fruit; the development of which deteriorates fruit quality, resulting in decreases in farmers' income.
Yeo-Jin Kang   +2 more
doaj   +1 more source

Identification of hub genes in rheumatoid arthritis through an integrated bioinformatics approach

open access: yesJournal of Orthopaedic Surgery and Research, 2021
Background Rheumatoid arthritis (RA) is a common chronic autoimmune disease characterized by inflammation of the synovial membrane. However, the etiology and underlying molecular events of RA are unclear.
Rui Wu   +5 more
doaj   +1 more source

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