Results 11 to 20 of about 925,682 (298)
Hunting for differentially expressed genes [PDF]
Differentially expressed genes are usually identified by comparing steady-state mRNA concentrations. Several methods have been used for this purpose, including differential hybridization, cDNA subtraction, differential display and, more recently, DNA ...
C.G. Vedoy, M.H. Bengtson, M.C. Sogayar
doaj +5 more sources
Detecting multivariate differentially expressed genes [PDF]
Background Gene expression is governed by complex networks, and differences in expression patterns between distinct biological conditions may therefore be complex and multivariate in nature.
Tegnér Jesper +3 more
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Differential gene expression in leiomyosarcoma [PDF]
AbstractBACKGROUNDLeiomyosarcomas (LMS) are a common subtype of soft tissue sarcoma. The molecular causes of the disease remain unclear.METHODSIn the current study, gene expression in LMS, leiomyomas, and normal myometrium was examined. RNA was prepared and gene expression was determined using microarray analysis arrays containing approximately 12,000 ...
Keith M, Skubitz, Amy P N, Skubitz
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GENE EXPRESSION IN DIFFERENTIATED CELLS [PDF]
This communication is concerned with the dynamics of gene control over specific biochemical functions in a differentiated cell. Direct experimental access to the intracellular link between gene action and the target cell characters has become feasible with the accumulation of evidence demonstrating that the synthesis of specific RNA's on the genomic ...
Davidson, E. H. +2 more
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Differential gene expression in mesothelioma [PDF]
To investigate the molecular events controlling malignant transformation of human pleural cells, we compared constitutive gene expression of mesothelioma cells to that of pleural cells. Using cDNA microarray and high‐density filter array, we assessed expression levels of >6500 genes.
Rihn, B.H. +7 more
openaire +2 more sources
Differential Gene Expression in Liver, Gill, and Olfactory Rosettes of Coho Salmon (Oncorhynchus kisutch) After Acclimation to Salinity. [PDF]
Most Pacific salmonids undergo smoltification and transition from freshwater to saltwater, making various adjustments in metabolism, catabolism, osmotic, and ion regulation. The molecular mechanisms underlying this transition are largely unknown.
Bammler, Theo K +8 more
core +1 more source
Gastric cancer (GC) is the third cause of cancer mortality in the world but the molecular mechanisms underlying the pathogenesis of GC remain little known.
Homa Akhavan +3 more
doaj +1 more source
Identification of Key Genes Between Lung Adenocarcinoma and Lung Squamous Cell Carcinoma by Bioinformatics Analysis [PDF]
Objective: To explore differentially expressed genes (DEGs) between lung adenocarcinoma (LUAD) and lung squamous cell carcinoma (LUSC).Methods: Based on GEO database, we used R software to identify the DEGs and conducted the bioinformatics analysis to ...
Jinru Xue, MS, Yu Yang, MS, Bo Jiang, MD, Linxue Qian, MD, Xian-Quan Shi, PhD
doaj +1 more source
Smoking affects gene expression in blood of patients with ischemic stroke. [PDF]
ObjectiveThough cigarette smoking (CS) is a well-known risk factor for ischemic stroke (IS), there is no data on how CS affects the blood transcriptome in IS patients.MethodsWe recruited IS-current smokers (IS-SM), IS-never smokers (IS-NSM), control ...
Ander, Bradley P +6 more
core +2 more sources
Differentially correlated genes in co-expression networks control phenotype transitions. [PDF]
BackgroundCo-expression networks are a tool widely used for analysis of "Big Data" in biology that can range from transcriptomes to proteomes, metabolomes and more recently even microbiomes.
Morgun, Andrey +4 more
core +2 more sources

