Results 51 to 60 of about 125,991 (267)
The parenting hub of the hypothalamus is a focus of imprinted gene action
PLOS Genetics, 2023 Imprinted genes are subject to germline epigenetic modification resulting in parental-specific allelic silencing. Although genomic imprinting is thought to be important for maternal behaviour, this idea is based on serendipitous findings from a small number of imprinted genes. Here, we undertook an unbiased systems biology approach, taking advantage of
Matthew J. Higgs +5 more
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Co-expression Network Analysis of Biomarkers for Adrenocortical Carcinoma
Frontiers in Genetics, 2018 Adrenocortical carcinoma (ACC) is a rare malignancy with a poor prognosis. And currently, there are no specific diagnostic biomarkers for ACC. In our study, we aimed to screen biomarkers for disease diagnosis, progression and prognosis.
Lushun Yuan +8 more
doaj +1 more source
Discovering New Hub Genes of Dilated Cardiomyopathy
ESC Heart FailureAbstract Aims Dilated cardiomyopathy (DCM) has a poor prognosis and exhibits a complex and diverse aetiology and genetic profile. The genes responsible for the pathogenesis of DCM have not been fully identified.
Jun-Yan Zhu +9 more
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Identification and Validation of Hub Genes in the Stenosis of Arteriovenous Fistula
Journal of Personalized Medicine, 2023 Arteriovenous fistula (AVF) is the most widely used hemodialysis vascular access in China. However, stenosis of the AVF limits its use. The mechanism of AVF stenosis is currently unknown. Therefore, the purpose of our study was to explore the mechanisms of AVF stenosis. In this study, we identified the differentially expressed genes (DEGs) based on the
Yu Li +8 more
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Journal of Inflammation Research, 2021 Ye Zhao,1,* Teng Ma,2,* Duowu Zou1 1Department of Gastroenterology, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, 200025, People’s Republic of China; 2Department of Thoracic Surgery, Zhongshan Hospital, Fudan ...
Zhao Y, Ma T, Zou D
doaj
Identification of biomarkers for Barcelona Clinic Liver Cancer staging and overall survival of patients with hepatocellular carcinoma. [PDF]
PLoS ONE, 2018 The aim of the current study was to identify biomarkers that correlate with the Barcelona Clinic Liver Cancer (BCLC) staging system and prognosis of patients with hepatocellular carcinoma (HCC).
Wei Xu +4 more
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Integrated Analysis of Hub Genes and miRNAs in Dilated Cardiomyopathy [PDF]
BioMed Research International, 2020 Purpose. The aim of this study is to identify hub genes and miRNAs by the miRNA‐mRNA interaction network in dilated cardiomyopathy (DCM) disease. Methods. The differentially expressed miRNAs (DEMis) and mRNAs (DEMs) were selected using data of DCM patients downloaded from the GEO database (GSE112556 and GSE3585). Gene Ontology (GO) pathway analysis and
Kai Huang +6 more
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Genomics Data, 2017 Human clear cell renal cell carcinoma (ccRCC) is one of the most common types of malignant adult kidney tumors. We constructed a weighted gene co-expression network to identify gene modules associated with clinical features of ccRCC (n = 97).
Lushun Yuan +6 more
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IET Systems Biology, 2022 This study aims to discover the genetic modules that distinguish glioblastoma multiforme (GBM) from low‐grade glioma (LGG) and identify hub genes. A co‐expression network is constructed using the expression profiles of 28 GBM and LGG patients from the ...
Dongdong Lin, Wei Li, Nu Zhang, Ming Cai
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Frontiers in Physiology, 2022 Based on multiple bioinformatics methods and machine learning techniques, this study was designed to explore potential hub genes of gastric cancer with a diagnostic value.
Qiu Chen, Yu Wang, Yongjun Liu, Bin Xi
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