Results 71 to 80 of about 10,923,960 (347)
Identification of Hub Genes in Tuberculosis via Bioinformatics Analysis [PDF]
Computational and Mathematical Methods in Medicine, 2021 Background. Tuberculosis (TB) is a serious chronic bacterial infection caused by Mycobacterium tuberculosis (MTB). It is one of the deadliest diseases in the world and a heavy burden for people all over the world. However, the hub genes involved in the host response remain largely unclear. Methods.
Tiancheng Zhang, Guihua Rao, Xiwen Gao
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Frontiers in Genetics, 2021 Despite the recent progress of lung adenocarcinoma (LUAD) therapy, tumor recurrence remained to be a challenging factor that impedes the effectiveness of treatment. The objective of the present study was to predict the hub genes affecting LUAD recurrence
Zhengze Shen +4 more
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Hub Gene Selection Methods for the Reconstruction of Transcription Networks [PDF]
, 2010 Abstract Transcription control networks have a scale-free topological structure: While most genes are involved in a reduced number of links, a few hubs or key regulators are connected to a significantly large number of nodes. Several methods have been developed for the reconstruction of these networks from gene expression data, e.g. ARACNE.
Hernandez-Lobato, J., Dijkstra, T.M.H.
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Evidence of Highly Regulated Genes (in-Hubs) in Gene Networks of Saccharomyces Cerevisiae [PDF]
Bioinformatics and Biology Insights, 2008 Uncovering interactions between genes, gene networks, is important to increase our understanding of intrinsic cellular processes and responses to external stimuli such as drugs. Gene networks can be computationally inferred from repeated measurements of gene expression, using algorithms, which assume that each gene is controlled by only a small number ...
Jesper Lundström +2 more
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Frontiers in Pharmacology, 2020 Esophageal adenocarcinoma (EAC) is a deadly cancer with high mortality rate, especially in economically advanced countries, while Barrett's esophagus (BE) is reported to be a precursor that strongly increases the risk of EAC.
Asma Sindhoo Nangraj +5 more
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Exploration of the hub genes and miRNAs in lung adenocarcinoma
Oncology Letters, 2019 In order to investigate the oncogenic mechanisms of lung adenocarcinoma (LUAD), hub genes can be identified by constructing co-expression networks, and the potential linkages between hub genes, transcription factors (TFs) and microRNAs (miRNAs/miRs) can be visualized and identified.
Zhai, Yuanyuan +3 more
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Italian Journal of MedicineSchizophrenia is thought to be the most prevalent chronic psychiatric disorder. Researchers have identified numerous proteins associated with the occurrence and development of schizophrenia. This study aimed to identify potential core genes and pathways
Iranna Kotturshetti +4 more
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BMC Medical Genomics, 2022 Objective This study identified underlying genetic molecules associated with histologically unstable carotid atherosclerotic plaques through bioinformatics analysis that may be potential biomarkers and therapeutic targets.
Julong Guo +4 more
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The parenting hub of the hypothalamus is a focus of imprinted gene action
PLOS Genetics, 2023 Imprinted genes are subject to germline epigenetic modification resulting in parental-specific allelic silencing. Although genomic imprinting is thought to be important for maternal behaviour, this idea is based on serendipitous findings from a small number of imprinted genes. Here, we undertook an unbiased systems biology approach, taking advantage of
Matthew J. Higgs +5 more
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united-manufacturing-hub/united-manufacturing-hub: v0.9.30
, 2023 <h2><a href="https://github.com/united-manufacturing-hub/united-manufacturing-hub/compare/v0.9.29...v0.9.30">0.9.30</a> (2023-11-20)</h2> <h3>Bug Fixes</h3> <ul> <li>bumped to 1 hour (<a href="https ...
kruegeralex +22 more
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