Results 81 to 90 of about 10,923,960 (347)

Co-expression Network Analysis of Biomarkers for Adrenocortical Carcinoma

open access: yesFrontiers in Genetics, 2018
Adrenocortical carcinoma (ACC) is a rare malignancy with a poor prognosis. And currently, there are no specific diagnostic biomarkers for ACC. In our study, we aimed to screen biomarkers for disease diagnosis, progression and prognosis.
Lushun Yuan   +8 more
doaj   +1 more source

Identification of biomarkers for Barcelona Clinic Liver Cancer staging and overall survival of patients with hepatocellular carcinoma. [PDF]

open access: yesPLoS ONE, 2018
The aim of the current study was to identify biomarkers that correlate with the Barcelona Clinic Liver Cancer (BCLC) staging system and prognosis of patients with hepatocellular carcinoma (HCC).
Wei Xu   +4 more
doaj   +1 more source

Discovering New Hub Genes of Dilated Cardiomyopathy

open access: yesESC Heart Failure
Abstract Aims Dilated cardiomyopathy (DCM) has a poor prognosis and exhibits a complex and diverse aetiology and genetic profile. The genes responsible for the pathogenesis of DCM have not been fully identified.
Jun-Yan Zhu   +9 more
openaire   +3 more sources

Identification and Validation of Hub Genes in the Stenosis of Arteriovenous Fistula

open access: yesJournal of Personalized Medicine, 2023
Arteriovenous fistula (AVF) is the most widely used hemodialysis vascular access in China. However, stenosis of the AVF limits its use. The mechanism of AVF stenosis is currently unknown. Therefore, the purpose of our study was to explore the mechanisms of AVF stenosis. In this study, we identified the differentially expressed genes (DEGs) based on the
Yu Li   +8 more
openaire   +2 more sources

Identification of Unique Transcriptomic Signatures and Hub Genes Through RNA Sequencing and Integrated WGCNA and PPI Network Analysis in Nonerosive Reflux Disease

open access: yesJournal of Inflammation Research, 2021
Ye Zhao,1,* Teng Ma,2,* Duowu Zou1 1Department of Gastroenterology, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, 200025, People’s Republic of China; 2Department of Thoracic Surgery, Zhongshan Hospital, Fudan ...
Zhao Y, Ma T, Zou D
doaj  

Co-expression network analysis identified six hub genes in association with progression and prognosis in human clear cell renal cell carcinoma (ccRCC)

open access: yesGenomics Data, 2017
Human clear cell renal cell carcinoma (ccRCC) is one of the most common types of malignant adult kidney tumors. We constructed a weighted gene co-expression network to identify gene modules associated with clinical features of ccRCC (n = 97).
Lushun Yuan   +6 more
doaj   +1 more source

ESRRG, ATP4A, and ATP4B as Diagnostic Biomarkers for Gastric Cancer: A Bioinformatic Analysis Based on Machine Learning

open access: yesFrontiers in Physiology, 2022
Based on multiple bioinformatics methods and machine learning techniques, this study was designed to explore potential hub genes of gastric cancer with a diagnostic value.
Qiu Chen, Yu Wang, Yongjun Liu, Bin Xi
doaj   +1 more source

Hub gene target of glioblastoma: LOX, SERPINH1 and TGFBI

open access: yesMedicine, 2022
Glioblastoma (GBM) is a malignant tumor. The long-term prognosis of the patients is poor. Therefore, it is of important clinical value to further explore the pathogenesis and look for molecular markers for early diagnosis and targeted treatment.
Shuyuan Zhang   +7 more
openaire   +2 more sources

Identification of KIF18B as a Hub Candidate Gene in the Metastasis of Clear Cell Renal Cell Carcinoma by Weighted Gene Co-expression Network Analysis

open access: yesFrontiers in Genetics, 2020
BackgroundClear cell renal cell carcinoma (ccRCC) is a common type of fatal malignancy in the urinary system. As the therapeutic strategies of ccRCC are severely limited at present, the prognosis of patients with metastatic carcinoma is usually not ...
Huiying Yang   +3 more
doaj   +1 more source

Bioinformatics analysis of common key genes and pathways of intracranial, abdominal, and thoracic aneurysms

open access: yesBMC Cardiovascular Disorders, 2021
Background Aneurysm is a severe and fatal disease. This study aims to comprehensively identify the highly conservative co-expression modules and hub genes in the abdominal aortic aneurysm (AAA), thoracic aortic aneurysm (TAA) and intracranial aneurysm ...
Siwei Bi   +4 more
doaj   +1 more source

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