Results 61 to 70 of about 124,378 (265)

Identification and Validation of Hub Genes in the Stenosis of Arteriovenous Fistula

Journal of Personalized Medicine, 2023
Arteriovenous fistula (AVF) is the most widely used hemodialysis vascular access in China. However, stenosis of the AVF limits its use. The mechanism of AVF stenosis is currently unknown. Therefore, the purpose of our study was to explore the mechanisms of AVF stenosis. In this study, we identified the differentially expressed genes (DEGs) based on the
Yu Li, Yue Chen, Wenhao Cui, Jukun Wang, Xin Chen, Chao Zhang, Linzhong Zhu, Chunjing Bian, Tao Luo   +8 more
openaire   +2 more sources

Rutin Effects on Human Senescent Stromal Cells Function: a Network Analysis Study [PDF]

Research Journal of Pharmacognosy
Background and objectives: Rutin is a lipophilic natural flavonoid. It is found in vegetables, citrus fruits, and beverages. This study aims to evaluate rutin metabolic pathways in human senescent stromal cells.
Reza Robati, Fatemeh Bandarian, Farideh Razi, Zahra Razzaghi, Mohammad Rostami Nejad, Mitra Rezaei, Babak Arjmand, Vahid Mansouri*   +7 more
doaj   +1 more source

Discovering New Hub Genes of Dilated Cardiomyopathy

ESC Heart Failure
Abstract Aims Dilated cardiomyopathy (DCM) has a poor prognosis and exhibits a complex and diverse aetiology and genetic profile. The genes responsible for the pathogenesis of DCM have not been fully identified.
Jun-Yan Zhu, Yu Han, Jing-Yu Yang, De-Ping Wang, Li-Juan Gao, Teng Sun, Yan-Lin Feng, Zhong-Mei He, Bin Zhou, Ji-Min Cao   +9 more
openaire   +3 more sources

Identification of hub genes associated with spermatogenesis by bioinformatics analysis

Scientific Reports, 2023
AbstractSpermatogenesis is a complex process related to male infertility. Till now, the critical genes and specific mechanisms have not been elucidated clearly. Our objective was to determine the hub genes that play a crucial role in spermatogenesis by analyzing the differentially expressed genes (DEGs) present in non-obstructive azoospermia (NOA ...
Shuang Liu, Yan-chao Bian, Wan-lun Wang, Tong-Jia Liu, Ting Zhang, Yue Chang, Rui Xiao, Chuan-ling Zhang   +7 more
openaire   +3 more sources

Identification of biomarkers for Barcelona Clinic Liver Cancer staging and overall survival of patients with hepatocellular carcinoma. [PDF]

PLoS ONE, 2018
The aim of the current study was to identify biomarkers that correlate with the Barcelona Clinic Liver Cancer (BCLC) staging system and prognosis of patients with hepatocellular carcinoma (HCC).
Wei Xu, Quan Rao, Yongbo An, Mengyi Li, Zhongtao Zhang   +4 more
doaj   +1 more source

ESRRG, ATP4A, and ATP4B as Diagnostic Biomarkers for Gastric Cancer: A Bioinformatic Analysis Based on Machine Learning

Frontiers in Physiology, 2022
Based on multiple bioinformatics methods and machine learning techniques, this study was designed to explore potential hub genes of gastric cancer with a diagnostic value.
Qiu Chen, Yu Wang, Yongjun Liu, Bin Xi
doaj   +1 more source

Bioinformatics analysis of common key genes and pathways of intracranial, abdominal, and thoracic aneurysms

BMC Cardiovascular Disorders, 2021
Background Aneurysm is a severe and fatal disease. This study aims to comprehensively identify the highly conservative co-expression modules and hub genes in the abdominal aortic aneurysm (AAA), thoracic aortic aneurysm (TAA) and intracranial aneurysm ...
Siwei Bi, Ruiqi Liu, Linfeng He, Jingyi Li, Jun Gu   +4 more
doaj   +1 more source

Therapeutic Apheresis in Nigeria: A Multi‐Center Summary of Abstracts From the Inaugural Nigerian Society for Apheresis Scientific Meeting

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Background Therapeutic apheresis (TA) is an established treatment modality for hematologic, neurologic, and immunologic disorders, yet access remains severely limited in sub‐Saharan Africa. Donor apheresis, including platelet apheresis collection from healthy donors, represents an important complementary modality supporting blood product ...
Nosa Bazuaye, Chimezie Okwuonu, Evelyn Idam, Folasade Adelekan‐Popoola, Shakirat Gold‐Olufadi, Olufunto Olufela Kalejaiye, Abdullateef Ogala, Zinnah Aloziem, Blossom Amamchukwu, Patience Elimia, Mkpoikanabasi Obot‐Obot, Henry Mbakwe, Praises Maduagwuna, Olatunji Akinrodoye, Chiamaka Anyanwu, Benjamin Anyanwu, Adedamola Akinsiku, Oluwatoyin A. Akinsiku, Muzamil O. Hassan, Fatiu A. Arogundade, Olalekan E. Ojo, Homayemem Weli, Jesupelumi Adenihun, Aderemi Adelaja, Ebun Bamgboye, Olalekan Olatise, Ade E. Faponle, Ayoola Odeyemi, Michael Muoka, Stephen Asaolu, Qudrat Busari, Blessing Dawudu, Michael Naiyeju, Rasheed A. Balogun   +33 more
wiley   +1 more source

Key genes and regulatory networks for diabetic retinopathy based on hypoxia-related genes: a bioinformatics analysis [PDF]

International Journal of Ophthalmology
AIM: To prevent neovascularization in diabetic retinopathy (DR) patients and partially control disease progression. METHODS: Hypoxia-related differentially expressed genes (DEGs) were identified from the GSE60436 and GSE102485 datasets, followed by gene ...
Cai-Han Yu, Cai-Xia Wu, Dai Li, Lan-Lan Gong, Xu-Dong Lyu, Jie Yang   +5 more
doaj   +1 more source

Identification of KIF18B as a Hub Candidate Gene in the Metastasis of Clear Cell Renal Cell Carcinoma by Weighted Gene Co-expression Network Analysis

Frontiers in Genetics, 2020
BackgroundClear cell renal cell carcinoma (ccRCC) is a common type of fatal malignancy in the urinary system. As the therapeutic strategies of ccRCC are severely limited at present, the prognosis of patients with metastatic carcinoma is usually not ...
Huiying Yang, Yukun Wang, Ziyi Zhang, Hua Li   +3 more
doaj   +1 more source