Results 11 to 20 of about 124,378 (265)
Prediction and analysis of osteoarthritis hub genes with bioinformatics
Annals of Translational Medicine, 2023 Osteoarthritis (OA) is the most common type of arthritis. OA can cause joint pain, stiffness, and loss of function. The pathogenesis of OA is not completely clear. Moreover, there is no effective treatment, and clinical management is limited to symptomatic relief or joint surgery.
Zhong, Junqing, Xiang, Ding, Ma, Xinlong
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Identification and validation of hub genes for diabetic retinopathy
PeerJ, 2021 Background Diabetic retinopathy (DR) is characterized by a gradually progressive alteration in the retinal microvasculature that leads to middle-aged adult acquired persistent blindness. Limited research has been conducted on DR pathogenesis at the gene level.
Peng, Li +3 more
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Frontiers in Immunology, 2022 BackgroundCalcific aortic valve disease (CAVD) is a progressive fibrocalcific disease that can be treated only through valve replacement. This study aimed to determine the role of hub genes and immune cell infiltration in CAVD progression.MethodsIn this ...
Kan Wang +5 more
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Hub Genes Associated with the Diagnosis of Diabetic Retinopathy
International Journal of General Medicine, 2021 This study aimed to identify genes that may be effective in diagnosing or treating diabetic retinopathy (DR), the most common complication of diabetes mellitus (DM).Differentially expressed genes (DEGs) were identified between DR and DM in GSE146615 dataset.
Yanhui Tang +6 more
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Frontiers in Molecular Neuroscience, 2022 Vascular dementia (VaD) is considered to be the second most common form of dementia after Alzheimer’s disease, and no specific drugs have been approved for VaD treatment.
Jun Shu, Wenshi Wei, Li Zhang
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Identification of potential hub genes of gastric cancer
Medicine, 2022 Abstract Background Gastric cancer (GC) is a malignant tumor originated from gastric mucosa epithelium. It is the third leading cause of cancer mortality in China. The early symptoms are not obvious. When it is discovered, it has developed to the advanced stage, and the prognosis is poor.
Xu-Dong Zhou +6 more
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Identification of hub genes related to prognosis in glioma [PDF]
Bioscience Reports, 2020 Abstract Glioma, a common malignant tumor of the central nervous system, has high invasiveness. The objective of the present study was to identify genes playing an important role in the development of glioma and to reveal their potential research value.
Delong Zhang +5 more
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Identification of hub genes and construction of diagnostic nomogram model in schizophrenia
Frontiers in Aging Neuroscience, 2022 Schizophrenia (SCZ), which is characterized by debilitating neuropsychiatric disorders with significant cognitive impairment, remains an etiological and therapeutic challenge.
Chi Zhang +4 more
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Screening of potential hub genes in pulmonary thromboembolism
Experimental and Therapeutic Medicine, 2021 Pulmonary thromboembolism (PTE) is a fatal clinical syndrome that usually occurs in elderly individuals. The present study aimed to identify functional and key genes involved in the early diagnosis of PTE using bioinformatics analysis. The GSE84738 dataset was retrieved from the Gene Expression Omnibus database.
Lu, Yan +4 more
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Network hub gene detection using the entire solution path information [PDF]
GeneticsMarkku Kuismin, Mikko J Sillanpää
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