Results 21 to 30 of about 43,312 (289)

Determining soft-threshold for WGCNA.

open access: yes, 2021
The WGCNA R package requires a user-defined soft-threshold (referred to as the “power” in the function call) based on visually observing the above graph; specifically, the scale-freeness. The first value above the threshold suggested by the WGCNA authors
Akul Singhania (502117)   +3 more
core   +1 more source

RETRACTED: Identification of Early Diagnostic and Prognostic Biomarkers via WGCNA in Stomach Adenocarcinoma [PDF]

open access: yesFrontiers in Oncology, 2021
Stomach adenocarcinoma (STAD) is a leading cause of cancer deaths, and the outcome of the patients remains dismal for the lack of effective biomarkers of early detection. Recent studies have elucidated the landscape of genomic alterations of gastric cancer and reveal some biomarkers of advanced-stage gastric cancer, however, information about early ...
Ruoyue Tan   +18 more
openaire   +3 more sources

WGCNA combined with GSVA to explore biomarkers of refractory neocortical epilepsy

open access: yesIBRO Neuroscience Reports, 2022
About two-thirds of epilepsy patients relapse within five years after surgery. It is significant to note that the limitations of current treatments stem from a lack of understanding of molecular mechanisms. In this study, Weighted Gene Co-expression Network Analysis (WGCNA) and Gene set variation analysis (GSVA) methods were used to analyze the total ...
Rui Zhang   +5 more
openaire   +3 more sources

WGCNA and molecular docking identify hub genes for cardiac aging

open access: yesFrontiers in Cardiovascular Medicine, 2023
BackgroundCardiac aging and ageing-related cardiovascular diseases remain increase medical and social burden. Discovering the molecular mechanisms associated with cardiac aging is expected to provide new perspectives for delaying aging and related disease treatment.MethodsThe samples in GEO database were divided into older group and younger group based
Ping Ping   +8 more
openaire   +3 more sources

WGCNA derived GECO Scores.

open access: yes, 2021
The table of GECO scores generated after clustering with WGCNA. (CSV)
Akul Singhania (502117)   +3 more
core   +1 more source

WGCNA Identification of Genes and Pathways Involved in the Pathogenesis of Postmenopausal Osteoporosis

open access: yesInternational Journal of General Medicine, 2021
Postmenopausal osteoporosis (PMO) patients may suffer from chronic pain and increased fractures due to brittle bones that seriously affect their normal work and life. Exploring the pathogenesis of PMO can help clinicians construct individualized therapeutic targets.Differentially expressed genes (DEGs) were identified by analyzing the microarray assays
Meng-Lei Hao   +3 more
openaire   +4 more sources

Identification of Survival-Associated Hub Genes in Pancreatic Adenocarcinoma Based on WGCNA [PDF]

open access: yesFrontiers in Genetics, 2022
Pancreatic adenocarcinoma is one of the leading causes of cancer-related death worldwide. Since little clinical symptoms were shown in the early period of pancreatic adenocarcinoma, most patients were found to carry metastases when diagnosis. The lack of effective diagnosis biomarkers and therapeutic targets makes pancreatic adenocarcinoma difficult to
Liya Huang   +6 more
openaire   +3 more sources

WGCNA supplement

open access: yes, 2022
Statistics accompanying WGCNA from mouse microarray expression of placental genes across gestational age timepoints (original dataset in Knox et al PMID 18340042).THIS DATASET IS ARCHIVED AT DANS/EASY, BUT NOT ACCESSIBLE HERE. TO VIEW A LIST OF FILES AND
Ciampa, E (via Mendeley Data)
core   +1 more source

Identification of Critical Modules and Biomarkers of Ulcerative Colitis by Using WGCNA

open access: yesJournal of Inflammation Research, 2023
Ulcerative colitis (UC) is a chronic inflammatory disease of the colon and rectum that has no exact cause and is characterized by relapsing and remitting episodes. We aimed to find biomarkers of UC and its causes.We got GSE73661 from the GEO database and used WGCNA to find DEGs that were expressed in the same way in both normal and UC samples.
Yuan,Yifan, Li,Na, Fu,Mingyue, Ye,Mei
openaire   +4 more sources

Regulators in WGCNA-derived co-expression modules.

open access: yes, 2023
Regulators in WGCNA-derived co-expression modules.
Shu Tu (12715426), Jian Zuo (306339)
core   +1 more source

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