Results 21 to 30 of about 43,312 (289)
Determining soft-threshold for WGCNA.
The WGCNA R package requires a user-defined soft-threshold (referred to as the “power” in the function call) based on visually observing the above graph; specifically, the scale-freeness. The first value above the threshold suggested by the WGCNA authors
Akul Singhania (502117) +3 more
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RETRACTED: Identification of Early Diagnostic and Prognostic Biomarkers via WGCNA in Stomach Adenocarcinoma [PDF]
Stomach adenocarcinoma (STAD) is a leading cause of cancer deaths, and the outcome of the patients remains dismal for the lack of effective biomarkers of early detection. Recent studies have elucidated the landscape of genomic alterations of gastric cancer and reveal some biomarkers of advanced-stage gastric cancer, however, information about early ...
Ruoyue Tan +18 more
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WGCNA combined with GSVA to explore biomarkers of refractory neocortical epilepsy
About two-thirds of epilepsy patients relapse within five years after surgery. It is significant to note that the limitations of current treatments stem from a lack of understanding of molecular mechanisms. In this study, Weighted Gene Co-expression Network Analysis (WGCNA) and Gene set variation analysis (GSVA) methods were used to analyze the total ...
Rui Zhang +5 more
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WGCNA and molecular docking identify hub genes for cardiac aging
BackgroundCardiac aging and ageing-related cardiovascular diseases remain increase medical and social burden. Discovering the molecular mechanisms associated with cardiac aging is expected to provide new perspectives for delaying aging and related disease treatment.MethodsThe samples in GEO database were divided into older group and younger group based
Ping Ping +8 more
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The table of GECO scores generated after clustering with WGCNA. (CSV)
Akul Singhania (502117) +3 more
core +1 more source
Postmenopausal osteoporosis (PMO) patients may suffer from chronic pain and increased fractures due to brittle bones that seriously affect their normal work and life. Exploring the pathogenesis of PMO can help clinicians construct individualized therapeutic targets.Differentially expressed genes (DEGs) were identified by analyzing the microarray assays
Meng-Lei Hao +3 more
openaire +4 more sources
Identification of Survival-Associated Hub Genes in Pancreatic Adenocarcinoma Based on WGCNA [PDF]
Pancreatic adenocarcinoma is one of the leading causes of cancer-related death worldwide. Since little clinical symptoms were shown in the early period of pancreatic adenocarcinoma, most patients were found to carry metastases when diagnosis. The lack of effective diagnosis biomarkers and therapeutic targets makes pancreatic adenocarcinoma difficult to
Liya Huang +6 more
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Statistics accompanying WGCNA from mouse microarray expression of placental genes across gestational age timepoints (original dataset in Knox et al PMID 18340042).THIS DATASET IS ARCHIVED AT DANS/EASY, BUT NOT ACCESSIBLE HERE. TO VIEW A LIST OF FILES AND
Ciampa, E (via Mendeley Data)
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Identification of Critical Modules and Biomarkers of Ulcerative Colitis by Using WGCNA
Ulcerative colitis (UC) is a chronic inflammatory disease of the colon and rectum that has no exact cause and is characterized by relapsing and remitting episodes. We aimed to find biomarkers of UC and its causes.We got GSE73661 from the GEO database and used WGCNA to find DEGs that were expressed in the same way in both normal and UC samples.
Yuan,Yifan, Li,Na, Fu,Mingyue, Ye,Mei
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Regulators in WGCNA-derived co-expression modules.
Regulators in WGCNA-derived co-expression modules.
Shu Tu (12715426), Jian Zuo (306339)
core +1 more source

