Results 31 to 40 of about 43,312 (289)
Identification of early diagnostic biomarkers via WGCNA in gastric cancer
Biomedicine & Pharmacotherapy, 2022 Gastric cancer (GC) is the world's second-leading cause of cancer-related mortality, continuing to make it a serious healthcare concern. Even though the prevalence of GC reduces, the prognosis for GC patients remains poor in terms of a lack of reliable biomarkers to diagnose early GC and predict chemosensitivity and recurrence.We integrated the gene ...
Rezaei Z. +9 more
openaire +3 more sources
WGCNA module cluster dendrogram and salmon module expression profile.
, 2023 (A) WGCNA module cluster dendrogram from bulk neutrophil RNA-seq. (B) Heatmap of WGCNA Salmon module gene expression from bulk neutrophil RNA-seq. S1 Table: Curated Gene Lists for ECM-related genes. (TIF)
Collin Y. Ewald (11740737) +2 more
core +1 more source
Identification of therapeutic targets and prognostic biomarkers in cholangiocarcinoma via WGCNA
Frontiers in Oncology, 2022 BackgroundCholangiocarcinoma (CCA) is a highly aggressive malignant tumor for which limited treatment methods and prognostic signatures are available. This study aims to identify potential therapeutic targets and prognostic biomarkers for CCA.MethodsBased on differentially expressed genes (DEGs) identified from The Cancer Genome Atlas (TCGA) data, our ...
Lei Xu, Ting Xiao, Ling Xu, Wei Yao
openaire +3 more sources
Overlap between k91 DICE clusters and WGCNA clusters.
, 2021 The x-axis shows the cluster numbers from the k91 DICE clusters, while the y-axis shows the cluster numbers from the WGCNA clusters. A. The overlap of genes from the sex-specific (Y-chromosome) ground truth set between the k91 DICE clusters and the WGCNA
Akul Singhania (502117) +3 more
core +1 more source
Identification of crucial genes in abdominal aortic aneurysm by WGCNA
PeerJ, 2019 Background Abdominal aortic aneurysm (AAA) is the full thickness dilation of the abdominal aorta. However, few effective medical therapies are available. Thus, elucidating the molecular mechanism of AAA pathogenesis and exploring the potential molecular target of medical therapies for AAA is of vital importance.
Siliang Chen +7 more
openaire +3 more sources
Identification of Latent Diagnostic Biomarkers and Biological Pathways in Dermatomyositis Based on WGCNA [PDF]
Journal of Oncology, 2021 Introduction. Dermatomyositis (DM) is a chronic autoimmune disease of predominantly lymphocytic infiltration mainly involving the transverse muscle. Its pathogenesis is remaining unknown. This research is designed to probe the latent pathogenesis of dermatomyositis, identify potential biomarkers, and reveal the pathogenesis of dermatomyositis through ...
Shaxi Ouyang +6 more
openaire +2 more sources
desilvakithmee/Research_GRN: wgcna
, 2020 <p>R codes used for preprocessing data, constructing gene regulatory networks using WGCNA and analysis of networks.</p ...
Kithmee de Silva
core +1 more source
Identification of Important Modules and Biomarkers in Breast Cancer Based on WGCNA.
OncoTargets and therapy, 2020 Breast cancer (BRCA) has the highest incidence among female malignancies, and the prognosis for these patients remains poor.In this study, core modules and central genes related to BRCA were identified through a weighted gene co-expression network analysis (WGCNA).
Tian,Zelin +6 more
openaire +3 more sources
Identification of the role of pyroptosis -related genes in chronic rhinosinusitis based on WGCNA
Heliyon, 2023 Abstract Background: Chronic rhinosinusitis (CRS) is a complex chronic inflammatory disease of the nose, paranasal sinus, and upper respiratory tract. Its treatment methods mainly include antibiotic treatment and surgical treatment. However, the molecular mechanism of its inflammation is still unclear. Pyroptosis is a programmed cell death.
Yarui Wan +4 more
openaire +3 more sources