Results 11 to 20 of about 31,790 (245)

Identification and Analysis of Potential Autophagy-Related Biomarkers in Endometriosis by WGCNA [PDF]

Frontiers in Molecular Biosciences, 2021
Background: Endometriosis is a serious gynecological disorder characterized by debilitating pain, infertility and the establishment of innervated endometriosis lesions outside the uterus. Early detection and accurate diagnosis are pivotal in endometriosis.
Jing Wang, Shanshan Cong, Han Wu, Yanan He, Xiaoli Liu, Liyuan Sun, Xibo Zhao, Guangmei Zhang   +7 more
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Identification of key genes in sepsis by WGCNA

Preventive Medicine, 2023
When the body damages its own tissues in response to an infection, sepsis develops. Medical treatments are limited. It's important to understand the molecular mechanism behind sepsis pathogenesis and identify potential molecular treatment targets. We made two modules based on how genes work together by using WGCNA analysis.
Xue-Meng, Gao, Xiu-Hua, Zhou, Meng-Wei, Jia, Xiao-Zhuo, Wang, Dan, Liu   +4 more
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WGCNA revisited: Module indetification

Journal of Physics: Conference Series, 2021
Abstract WGCNA is a very popular R language software package used in biomedical field. It is mainly designed to deal with gene microarray samples to find clusters (modules), which include highly correlated genes, in biomedical studies. Theoretically, it results in the hierarchical modules, which are different from the results based on ...
Shaomin Yan, Guang Wu
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Identification and Validation of Pivotal Genes in Osteoarthritis Combined with WGCNA Analysis

Journal of Inflammation Research
Chengzhuo Yang,1,* Xinhua Chen,1,* Jin Liu,1 Wenhao Wang,1 Lihua Sun,2 Youhong Xie,1 Qing Chang1,* 1Department of The Affiliated Rehabilitation Hospital of Chongqing Medical University, Chongqing, People’s Republic of China; 2Department of ...
Yang C, Chen X, Liu J, Wang W, Sun L, Xie Y, Chang Q   +6 more
doaj   +3 more sources

WGCNA: an R package for weighted correlation network analysis [PDF]

BMC Bioinformatics, 2008
(Uploaded by Plazi for the Bat Literature Project) Correlation networks are increasingly being used in bioinformatics applications. For example, weighted gene co-expression network analysis is a systems biology method for describing the correlation patterns among genes across microarray samples. Weighted correlation network analysis (WGCNA) can be used
Horvath Steve, Langfelder Peter
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WGCNA Identification of Genes and Pathways Involved in the Pathogenesis of Postmenopausal Osteoporosis

International Journal of General Medicine, 2021
Postmenopausal osteoporosis (PMO) patients may suffer from chronic pain and increased fractures due to brittle bones that seriously affect their normal work and life. Exploring the pathogenesis of PMO can help clinicians construct individualized therapeutic targets.Differentially expressed genes (DEGs) were identified by analyzing the microarray assays
Meng-Lei Hao, Xiao-Qin Zuo, Yong Qiu, Jian Li   +3 more
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RETRACTED: Identification of Early Diagnostic and Prognostic Biomarkers via WGCNA in Stomach Adenocarcinoma [PDF]

Frontiers in Oncology, 2021
Stomach adenocarcinoma (STAD) is a leading cause of cancer deaths, and the outcome of the patients remains dismal for the lack of effective biomarkers of early detection. Recent studies have elucidated the landscape of genomic alterations of gastric cancer and reveal some biomarkers of advanced-stage gastric cancer, however, information about early ...
Ruoyue Tan, Ruoyue Tan, Ruoyue Tan, Guanghui Zhang, Guanghui Zhang, Ruochen Liu, Ruochen Liu, Jianbing Hou, Jianbing Hou, Zhen Dong, Zhen Dong, Chaowei Deng, Chaowei Deng, Sicheng Wan, Sicheng Wan, Xiaodong Lai, Hongjuan Cui, Hongjuan Cui, Hongjuan Cui   +18 more
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Identification of key pathways and genes in nasopharyngeal carcinoma based on WGCNA

Auris Nasus Larynx, 2023
We aim to identify the potential genes and signaling pathways associated with the nasopharyngeal carcinoma (NPC) prognosis using Weighted Gene Co-Expression Network Analysis (WGCNA).Gene Expression Omnibus (GEO) query was utilized to download two NPC mRNA microarray data.
Yongmei, Dai, Wenhan, Chen, Junpeng, Huang, Li, Xie, Jianfang, Lin, Qianshun, Chen, Guicheng, Jiang, Chen, Huang   +7 more
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Identification of Survival-Associated Hub Genes in Pancreatic Adenocarcinoma Based on WGCNA [PDF]

Frontiers in Genetics, 2022
Pancreatic adenocarcinoma is one of the leading causes of cancer-related death worldwide. Since little clinical symptoms were shown in the early period of pancreatic adenocarcinoma, most patients were found to carry metastases when diagnosis. The lack of effective diagnosis biomarkers and therapeutic targets makes pancreatic adenocarcinoma difficult to
Liya Huang, Ting Ye, Jingjing Wang, Xiaojing Gu, Ruiting Ma, Lulu Sheng, Binwu Ma   +6 more
openaire   +3 more sources

Identification of Critical Modules and Biomarkers of Ulcerative Colitis by Using WGCNA

Journal of Inflammation Research, 2023
Ulcerative colitis (UC) is a chronic inflammatory disease of the colon and rectum that has no exact cause and is characterized by relapsing and remitting episodes. We aimed to find biomarkers of UC and its causes.We got GSE73661 from the GEO database and used WGCNA to find DEGs that were expressed in the same way in both normal and UC samples.
Yuan,Yifan, Li,Na, Fu,Mingyue, Ye,Mei
openaire   +4 more sources