Results 51 to 60 of about 31,790 (245)

Weighted Gene Co-Expression Network of Growth Differentiation-Related lncRNAs and mRNAs in Plectropomus leopardus

Progress in Fishery Sciences
The leopard coral grouper (Plectropomus leopardus) exhibits captivating chromatic patterns and boasts substantial nutritional content. This species garners significant consumer preference owing to its aesthetic appeal and nutritional richness, thereby ...
Jin GAO, Jinye LIU, Fuxiao CHEN, Yongbo WANG, Shuyuan FU   +4 more
doaj   +1 more source

Exploring Prognosis-Associated Biomarkers of Estrogen-Independent Uterine Corpus Endometrial Carcinoma by Bioinformatics Analysis

International Journal of General Medicine, 2021
Youchun Ye, Hongfeng Li, Jia Bian, Liangfei Wang, Yijie Wang, Hui Huang Department of Gynecology and Obstetrics, The Affiliated People’s Hospital of Ningbo University, Ningbo, Zhejiang, 315040, People’s Republic of ChinaCorrespondence: Youchun ...
Ye Y, Li H, Bian J, Wang L, Wang Y, Huang H   +5 more
doaj  

Calcineurin‐Dependent Stress Adaptation Enables Caspofungin Heteroresistance Leading to Stable Resistance in Candida Glabrata

Advanced Science, EarlyView.
Caspofungin heteroresistance is prevalent in clinical Candida glabrata isolates and depends on calcineurin‐mediated stress adaptation. This transient phenotype serves as a reservoir for resistance evolution, enabling the emergence of stable resistant descendants under prolonged drug pressure.
Yanyu Su, Yi Li, Meng Xiao, Dan Guo, David S. Perlin, Erika Shor, Yingchun Xu, Yingxing Li   +7 more
wiley   +1 more source

Comparative transcriptomic and weighted gene co-expression network analysis to identify the core genes in the cultivars of Musa acuminata under both infected and chemical perturbated conditions

Plant Signaling & Behavior, 2023
Banana is a high nutrient crop, which ranks fourth in terms of gross value production. Fusarium wilt of banana, caused by Fusarium oxysporum f. sp. cubense tropical race 4 (FocTR4), is considered the most destructive disease leading to the complete loss ...
PTV Lakshmi, Amrendra Kumar, Ajna A. S., Abitha P Raveendran, Anjali Chaudhary, Adhitthan Shanmugam, Annamalai Arunachalam   +6 more
doaj   +1 more source

Co-expression modules construction by WGCNA and identify potential hub genes and regulation pathways of postpartum depression

Frontiers in Bioscience-Landmark, 2021
Purpose: The purpose of our present study was to, for the first time, identify key genes associated with postpartum depression (PPD) and discovery the potential molecular mechanisms of this condition.
Zhifang Deng, Wei Cai, Jue Liu, Aiping Deng, Yuan Yang, Jie Tu, Cheng Yuan, Han Xiao, Wenqi Gao   +8 more
doaj   +1 more source

Identification of crucial genes through WGCNA in the progression of gastric cancer

Journal of Cancer
Background: To explore the hub gene closely related to the progression of gastric cancer (GC), so as to provide a theoretical basis for revealing the therapeutic mechanism of GC. Methods: The gene expression profile and clinical data of GSE15459 in Gene Expression Omnibus (GEO) database were downloaded. The weighted gene co-expression network analysis (
Liu, Rui, Liu, Jie, Cao, Qiang, Chu, Yanpeng, Chi, Hao, Zhang, Jun, Fu, Jiangping, Zhang, Tianchi, Fan, Linguang, Liang, Chaozhong, Luo, Xiufang, Yang, Xiaoli, Li, Bo   +12 more
openaire   +2 more sources

Multi‐tissue Metabolic GWAS and Drought‐Responsive Multi‐omics Reveal the Genetic Basis of the Quinoa Metabolome

Advanced Science, EarlyView.
A multi‐omics framework combining multitissue genome‐wide association studies, metabolomics, transcriptomics, proteomics, and functional validation uncovers the genetic basis of specialized metabolism in quinoa. The study identifies hundreds of metabolite‐associated loci, prioritizes candidate genes for saponin, betalain, and flavonoid biosynthesis ...
Julia von Steimker, Elodie L. Rey, Clara Stanschewski, Regina Wendenburg, Annabella Klemmer, Markéta Macho, Venkatesh P. Thirumalaikumar, Noha O. Saber, Aleksandra Skirycz, Alisdair R. Fernie, Mark Tester, Saleh Alseekh   +11 more
wiley   +1 more source

Profiling the accumulation of ten bioactive compounds in Rheum officinale across different growth years using integrated HPLC and transcriptomic approaches

Medicinal Plant Biology
Rheum officinale is a prominent traditional medicinal herb in the Chinese Pharmacopeia. Variations in the composition and accumulation of secondary metabolites in R. officinale have been observed to correlate with harvest periods. This study investigated
Yi-min Li, Xue-ru Wang, Ge Yang, Ting-ting Yan, Xiao-chen Hu, Liang Peng, Jing Gao, Feng Yan, Gang Zhang   +8 more
doaj   +1 more source

Exploration and Validation of Pancreatic Cancer Hub Genes Based on Weighted Gene Co-Expression Network Analysis and Immune Infiltration Score Analysis

Pharmacogenomics and Personalized Medicine, 2023
Xiao-Xi Li,1,* Hong Li,2,* Li-Quan Jin,3 Yun-Bo Tan1,3 1Dali University of Clinical Medicine School, Dali, Yunnan, 671000, People’s Republic of China; 2Department of Radiology, Affiliated Renhe Hospital of China Three Gorges University, Hubei ...
Li XX, Li H, Jin LQ, Tan YB
doaj  

A Pan‐Methylome Framework for Population‐Scale Bacterial Epigenomics

Advanced Science, EarlyView.
A scalable quantitative framework unlocks population‐level comparative epigenomics in bacteria. By transforming site‐level data into standardized traits, this approach reconstructs methylation‐informed phylogenies and defines the core epigenome.
Bin Ma, Huimin Gong, Ran Zhuo, Zaixiao Rao, Yanxi Wan, Mingyang Wang, Zahra Zeinalzadeh, Yuan Gao, Aohan Guan, Xinrun Li, Wanting Chen, Xiliang Wang, Yun Wan, Sihua Zhang, Yuncai Xiao, Qi Huang, Paul R. Langford, Xiangru Wang, Rui Zhou, Rui Luo, Hongbo Zhou, Chengliang Zhu, Hui Jin   +22 more
wiley   +1 more source