Results 71 to 80 of about 33,188 (253)

The process of screening TC-related mRNAs using WGCNA.

, 2022
(a) Hierarchical clustering for TC samples constructed based on their mRNA expression levels. (b) Selecting for soft threshold(power). When the power value is 7, the degree of independence was > 0.8 for the first time.
Bo Wang (86769), Xiaodong Zheng (122836), Runjie Liu (13184224), Wei Jiang (14986), Yu Han (251741)   +4 more
core   +1 more source

Beyond “you are what you eat”: Unlocking gut microbiota‐mediated biotransformation of dietary phytochemicals

iMetaOmics, EarlyView.
The “efficacy paradox” of phytochemicals, low bioavailability yet significant health benefits, is associated with gut microbiota, which biotransforms dietary precursors into bioactive metabolites, enabling systemic effects. Thus, health outcomes of diet depend not just on intake “the rainbow”, but on gut microbial metabolism, redefining “you are what ...
Peng Yang, Ren‐You Gan
wiley   +1 more source

AMPEL BioSolutions Weighted Correlation Network Analysis WGCNA Code.txt

, 2019
AMPEL BioSolutions WGCNA code used in publications of bioinformatic analyses of ...
Michelle Catalina (6407291)
core   +1 more source

Identification and Validation of Pivotal Genes in Osteoarthritis Combined with WGCNA Analysis

Journal of Inflammation Research
The prevalence of osteoarthritis (OA), the most common chronic joint condition, is increasing due to the aging population and escalating obesity rates, leading to a significant impact on human health and well-being. Thus, analyzing the key targets of OA through bioinformatics can help discover new biomarkers to improve its diagnosis.The microarray and ...
Chengzhuo Yang, Xinhua Chen, Jin Liu, Wenhao Wang, Lihua Sun, Youhong Xie, Qing Chang   +6 more
openaire   +4 more sources

Integrated high‐throughput phenomics and transcriptomics uncover the transcriptional mechanisms underlying rice responses to elevated CO2 concentration and cadmium stress

iMetaOmics, EarlyView.
Developing crop varieties with reduced cadmium (Cd) accumulation under elevated carbon dioxide (eCO2) requires hub gene identification and elucidation of its transcriptional mechanisms. Here, we acquired high‐throughput phenotyping of the rice cultivar Nipponbare across six key developmental stages under Cd stress and three eCO2 concentrations.
Weijun Guo, Hanlin Liu, Dongwei Li, Shang Xie, Yichao Mao, Liwen Yang, Cong Li, Weixuan Wang, Jian Tian, Xiaofeng Gu, Li Pu   +10 more
wiley   +1 more source

Gene Expression Analyses in R (limma and WGCNA)

, 2018
Data files and R-scripts for gene expression analyses (limma and ...
Hofmann, Gretchen E., Kelly, Morgan W., Wong, Juliet M., Juliet M. Wong (5015432), Gretchen E. Hofmann (290887), Johnson, Kevin M., Morgan W. Kelly (3200163), Kevin M. Johnson (1310253)   +7 more
core   +1 more source

Changes in the gut microbiome during fasting‐induced molting and its effects on gut–liver function

iMetaOmics, EarlyView.
During fasting, harmful microbiota and metabolites rise, triggering intestinal injury and activation of the TGF‐β signaling pathway, which enhances intestinal stem cell proliferation. Concurrently, hepatic function declines, indicated by increased hepatic and serum bile acids and upregulation of the non‐classical bile acid synthesis pathway.
Hao Zhang, Zhixuan Luo, Jun Zhang, Chenxu Wang, Yadong Tian, Donghua Li, Yujie Guo, Yanhua Zhang, Wenting Li, Yujie Gong, Xiangtao Kang, Ruirui Jiang   +11 more
wiley   +1 more source

Microbial keystone taxa and metabolic signatures in centenarians regulate intestinal homeostasis during aging

iMeta, EarlyView.
Clostridium scindens and its metabolite indole‐3‐acetic acid (IAA) are identified as a keystone taxon and metabolic signature in centenarians. Clostridium scindens enhances microbial network stability and produces IAA via its own amidase (AMIE) and aldehyde dehydrogenase (ALDH), thus promoting intestinal homeostasis by activating the aryl hydrocarbon ...
Wei‐Chuan Lin, Cui Zhang, He‐Hua Lei, Zheng Cao, Xin Gao, Wen‐Kai Yu, Xin‐Zhi Li, Qing‐Wei Xiang, Zhi‐Wen Zhang, Shi‐Fu Pang, Wei‐Fei Luo, Deng‐Hui Xie, Li‐Min Zhang, Gang Chen   +13 more
wiley   +1 more source

Functional analysis of key expression patterns of WGCNA.

, 2019
A) Expression patterns of different modules of WGCNA; B) KO enrichment bubble diagram of genes in darkorange2 module; C) KO enrichment bubble diagram of genes in honeydew1 module.
Aigai Zhang (6852167), Haitao Yan (291625), Zhengyang Niu (6852164), Guoshun Liu (2624512), Shen Yan (3999935)   +4 more
core   +1 more source

Six miRNAs related to liver fibrosis were screened from WGCNA analysis.

, 2023
Six miRNAs related to liver fibrosis were screened from WGCNA analysis.
Juan Hu (676613), Han Liu (288039), Longchun Mao (15909689), Zhiqiang Li (102723), Shangcheng Xu (533704), Qinli Pu (15909686), Wei Wang (17594), Cong Xie (572474), Liping Yang (156318), Weixian Chen (597632)   +9 more
core   +1 more source