Results 71 to 80 of about 47,201 (334)

Exploring Prognosis-Associated Biomarkers of Estrogen-Independent Uterine Corpus Endometrial Carcinoma by Bioinformatics Analysis

International Journal of General Medicine, 2021
Youchun Ye, Hongfeng Li, Jia Bian, Liangfei Wang, Yijie Wang, Hui Huang Department of Gynecology and Obstetrics, The Affiliated People’s Hospital of Ningbo University, Ningbo, Zhejiang, 315040, People’s Republic of ChinaCorrespondence: Youchun ...
Ye Y, Li H, Bian J, Wang L, Wang Y, Huang H   +5 more
doaj  

Persistently Increased Expression of PKMzeta and Unbiased Gene Expression Profiles Identify Hippocampal Molecular Traces of a Long‐Term Active Place Avoidance Memory and “Shadow” Proteins

Advanced Science, EarlyView.
Protein complexes like KIBRA‐PKMζ are crucial for maintaining memories, forming month‐long protein traces in memory‐tagged neurons, but conventional RNA‐seq analysis fails to detect their transcript changes, leaving memory molecules undetected in the shadows of abundantly‐expressed genes.
Jiyeon Han, Alejandro Grau‐Perales, Rayna M. Harris, Edith Lesburguères, Hsin‐Yi Kao, Asit Pal, Juan Marcos Alarcon, Todd C. Sacktor, Stefano Martiniani, Hans A. Hofmann, André A. Fenton   +10 more
wiley   +1 more source

Identification of thyroid cancer biomarkers using WGCNA and machine learning

European Journal of Medical Research
The incidence of thyroid cancer (TC) is increasing in China, largely due to overdiagnosis from widespread screening and improved ultrasound technology. Identifying precise TC biomarkers is crucial for accurate diagnosis and effective treatment.TC patient data were obtained from TCGA.
Gaofeng Hu, Wenyuan Niu, Jiaming Ge, Jie Xuan, Yanyang Liu, Mengjia Li, Huize Shen, Shang Ma, Yuanqiang Li, Qinglin Li   +9 more
openaire   +3 more sources

Weighted Gene Co-Expression Network of Growth Differentiation-Related lncRNAs and mRNAs in Plectropomus leopardus

Progress in Fishery Sciences
The leopard coral grouper (Plectropomus leopardus) exhibits captivating chromatic patterns and boasts substantial nutritional content. This species garners significant consumer preference owing to its aesthetic appeal and nutritional richness, thereby ...
Jin GAO, Jinye LIU, Fuxiao CHEN, Yongbo WANG, Shuyuan FU   +4 more
doaj   +1 more source

Comparative transcriptomic and weighted gene co-expression network analysis to identify the core genes in the cultivars of Musa acuminata under both infected and chemical perturbated conditions

Plant Signaling & Behavior, 2023
Banana is a high nutrient crop, which ranks fourth in terms of gross value production. Fusarium wilt of banana, caused by Fusarium oxysporum f. sp. cubense tropical race 4 (FocTR4), is considered the most destructive disease leading to the complete loss ...
PTV Lakshmi, Amrendra Kumar, Ajna A. S., Abitha P Raveendran, Anjali Chaudhary, Adhitthan Shanmugam, Annamalai Arunachalam   +6 more
doaj   +1 more source

Co-expression modules construction by WGCNA and identify potential hub genes and regulation pathways of postpartum depression

Frontiers in Bioscience-Landmark, 2021
Purpose: The purpose of our present study was to, for the first time, identify key genes associated with postpartum depression (PPD) and discovery the potential molecular mechanisms of this condition.
Zhifang Deng, Wei Cai, Jue Liu, Aiping Deng, Yuan Yang, Jie Tu, Cheng Yuan, Han Xiao, Wenqi Gao   +8 more
doaj   +1 more source

Spatiotemporal dynamics of the postnatal developing primate brain transcriptome. [PDF]

, 2015
Developmental changes in the temporal and spatial regulation of gene expression drive the emergence of normal mature brain function, while disruptions in these processes underlie many neurodevelopmental abnormalities.
Amaral, David G, Bakken, Trygve E, Bennett, Jeffrey L, Bernard, Amy, Bertagnolli, Darren, Geschwind, Daniel H, Lee, Chang-Kyu, Lein, Ed S, Luo, Rui, Miller, Jeremy A, Parikshak, Neelroop N, Smith, Kimberly A, Sunkin, Susan M   +12 more
core   +1 more source

Alzheimer's Disease Risk Factor APOE4 Exerts Dimorphic Effects on Female Bone

Advanced Science, EarlyView.
In aging bone, osteocytes accumulate neurodegenerative risk factor Apolipoprotein E (APOE). A humanized version of the Alzheimer's disease risk allele APOE4 altered the mouse bone transcriptome and proteome, with effects in female bone surpassing the brain, including bone fragility due to suppressed osteocytic maintenance of bone quality, identifying ...
Charles A. Schurman, Gurcharan Kaur, Serra Kaya, Joanna Bons, Carlos Galicia Aguirre, Qi Liu, Christina D. King, Kenneth A. Wilson, Harrison L. Baker, Mikayla Hady, Nadja Maldonado Luna, Gregor Bieri, Saul A. Villeda, Lisa M. Ellerby, Birgit Schilling, Tamara Alliston   +15 more
wiley   +1 more source

Exploration and Validation of Pancreatic Cancer Hub Genes Based on Weighted Gene Co-Expression Network Analysis and Immune Infiltration Score Analysis

Pharmacogenomics and Personalized Medicine, 2023
Xiao-Xi Li,1,* Hong Li,2,* Li-Quan Jin,3 Yun-Bo Tan1,3 1Dali University of Clinical Medicine School, Dali, Yunnan, 671000, People’s Republic of China; 2Department of Radiology, Affiliated Renhe Hospital of China Three Gorges University, Hubei ...
Li XX, Li H, Jin LQ, Tan YB
doaj  

Modeling the functional genomics of autism using human neurons. [PDF]

, 2012
Human neural progenitors from a variety of sources present new opportunities to model aspects of human neuropsychiatric disease in vitro. Such in vitro models provide the advantages of a human genetic background combined with rapid and easy manipulation,
Chen, L, Gao, F, Gao, K, Geschwind, DH, Konopka, G, Lowe, JK, Lu, D, Mukamel, Z, Osborn, GE, Rosen, E, Wexler, E   +10 more
core   +1 more source