Results 91 to 100 of about 43,312 (289)
Cells, 2020 Environmental food contaminants constitute a threat to human health. For instance, the globally spread mycotoxin Ochratoxin A (OTA) contributes to chronic kidney damage by affecting proximal tubule cells via unknown mechanisms.
Virginie Dubourg +4 more
doaj +1 more source
Advanced Science, EarlyView.Synovial macrophages in osteoarthritis upregulate LSP1, which directly binds and inhibits SOD1, triggering a redox imbalance that activates both NOX and mitochondrial ROS pathways. This cascade drives the release of macrophage extracellular traps (METs), causing chondrocyte damage and disease progression.
Yankai Pan +9 more
wiley +1 more source
Variance stabilized gene expression data for WGCNA
, 2015 Variance stabilized gene expression data for all samples from the top differentially expressed genes (unadjusted p-value < 0.1) for network analysis with the R package WGCNA. Rows are genes.
Mikhail V. Matz (51701) +3 more
core +1 more source
Animal Models and Experimental Medicine, EarlyView.Our study systematically explored the anti‐gastric cancer (GC) mechanism of Xanthotoxol (Xan), a natural active phytochemical, using an integrated strategy of network pharmacology, molecular simulation, and experimental validation. First, we identified 39 hub genes associated with gastric cancer using weighted gene co‐expression network analysis (WGCNA)
Yi Yang +10 more
wiley +1 more source
Association of DPP4 with esophageal stricture progression and the Hippo‐YAP pathway
Animal Models and Experimental Medicine, EarlyView.This study establishes a comprehensive translational platform for esophageal stricture (ES) research by integrating a novel rat model with clinically relevant porcine validation. This study identifies DPP4 as a gene of interest associated with ES following endoscopic submucosal dissection, demonstrating that prophylactic DPP4 inhibition attenuates ...
Rui Wu +5 more
wiley +1 more source
Exploring qpcr data with weighted gene coexpression network analysis (WGCNA)
, 2015 Differently expressed genes e.g. in a disease may play a role in the etiology or progression of the disease. The traditional approach of finding differentially expressed genes is to compare the expression levels in the groups, and produce a list of ...
Morland, Sara
core +2 more sources
Cancer Management and Research, 2023 ZhenDong Liu,1 YuYang Xu,1 Shan Jin,2 Xin Liu,1 BaoChun Wang1 1Department of General Surgery, Hainan General Hospital, Hainan Affiliated Hospital of Hainan Medical University, Haikou, Hainan Province, People’s Republic of China; 2Department of ...
Liu Z, Xu Y, Jin S, Liu X, Wang B
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, 2023 WGCNA modules, number of transcripts with significant correlations, hub transcription factors and hub genes.
Pengmin Wang (17008362) +2 more
core +1 more source
Animal Research and One Health, EarlyView.This study delineates the early sex differentiation timeline in the northern snakehead (Channa argus). These findings provide a foundation for future sex‐control breeding in this economically important species. ABSTRACT The northern snakehead (Channa argus) is an economically important aquaculture species in China.
Chaonan Sun +6 more
wiley +1 more source
Pharmacogenomics and Personalized Medicine, 2022 Pei Chen, Mengyun Yao, Tao Fang, Chaoshuang Ye, Yongjiang Du, Yang Jin, Ruijin Wu Department of Obstetrics and Gynecology, Women’s Hospital, Zhejiang University School of Medicine, Hangzhou, People’s Republic of ChinaCorrespondence: Ruijin Wu, Department
Chen P +6 more
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