Results 101 to 110 of about 43,312 (289)

AMPEL BioSolutions Weighted Correlation Network Analysis WGCNA Code.txt

, 2019
AMPEL BioSolutions WGCNA code used in publications of bioinformatic analyses of ...
Michelle Catalina (6407291)
core   +1 more source

WGCNA analysis of the subcutaneous fat transcriptome in a novel tree shrew model

Experimental Biology and Medicine, 2020
Obesity involves genetic and environmental factors. The co-expression gene network in relevant tissues in different obesity groups provides an entrance for profiling and identifying associated pathways and genes. We aim to identify the meaningful co-expressed gene network in mRNA extracted from adipose tissues representing different obesity phenotypes ...
Yuanyuan Han, Wenguang Wang, Jie Jia, Xiaomei Sun, Dexuan Kuang, Pinfen Tong, Na Li, Caixia Lu, Huatang Zhang, Jiejie Dai   +9 more
openaire   +3 more sources

ZBED6 Knockout Promotes Skeletal Muscle Development in Bama Pigs by Relieving Transcriptional Repression of CDKN1A

Animal Research and One Health, EarlyView.
Integrated transcriptomic and functional analyses identify CDKN1A as a direct target of ZBED6 in Bama pigs. ZBED6 knockout relieves transcriptional repression of CDKN1A, thereby promoting myogenic differentiation and skeletal muscle development.
Yitian Ma, Xiu Lin, Pengtao Yuan, Yabin Pu, Yuehui Ma, Zixiao Jiang, Lin Jiang, Chongyang Li, Dandan Wang   +8 more
wiley   +1 more source

Comparative Analysis of Salmonella typhimurium‐Induced Transcriptomic Changes in the Spleen of Beijing‐You Chickens and Guang Ming Broilers

Animal Research and One Health, EarlyView.
This study analyzed the spleen transcriptomes of different chicken breeds, identified key differentially expressed genes (EGR1, FOS, and DUSP1) that regulate resistance to Salmonella infection, and elucidated the underlying regulatory mechanisms, thereby providing new targets for disease‐resistant breeding in poultry.
Zixuan Wang, Man Deng, He Geng, Jumei Zheng, Xiang Li, Yaping Wang, Qinghe Li, Guiping Zhao, Qiao Wang   +8 more
wiley   +1 more source

Pathophysiological Mechanisms of Emaciation Syndrome in Plectropomus leopardus: Insights From Histology and Transcriptomics

Animal Research and One Health, EarlyView.
Integrated phenotypic, histological, transcriptomic, and validation analyses reveal that emaciation syndrome in Plectropomus leopardus is associated with intestinal structural damage, hepatic metabolic remodeling, and muscle protein degradation, highlighting coordinated multi‐tissue alterations underlying disease progression.
Zhihao Zhang, Bo Wang, Mengya Wang, Haizhan Tang, Mingjian Liu, Da Zheng, Zhongyi Zhai, Jiahang Li, Jinyang Xie, Chaofan Jin, Jingjie Hu, Zhenmin Bao   +11 more
wiley   +1 more source

Comparison of WGCNA expression by tissue and module.

, 2019
Comparison of WGCNA expression by tissue and module.
Pouya Dini (6109472), Hossam El-Sheikh Ali (7866251), Theodore Kalbfleisch (59077), Barry A. Ball (3912946), Shavahn C. Loux (3912937)   +4 more
core   +1 more source

Cumulative Reproductive‐Lactation Burdens Induce a Systemic Immunometabolic Trade‐Off Between Milk Yield and Mammary Health of Dairy Cows

Animal Research and One Health, EarlyView.
A population‐scale longitudinal transcriptomic atlas reveals how lactation stage and parity reshape systemic gene regulation in dairy cows. Multiomics‐inspired analyses uncover dynamic immune and metabolic adaptations that contribute to reproductive longevity and sustained productivity across the bovine lifespan.
Yangyang Shen, Zhenjiang An, Yingying Jiang, Zijian Huang, Kunlin Chen, Yundong Gao, Jianbin Li, Shuwen Xia, Huili Wang   +8 more
wiley   +1 more source

Gene Expression Analyses in R (limma and WGCNA)

, 2018
Data files and R-scripts for gene expression analyses (limma and ...
Hofmann, Gretchen E., Kelly, Morgan W., Wong, Juliet M., Juliet M. Wong (5015432), Gretchen E. Hofmann (290887), Johnson, Kevin M., Morgan W. Kelly (3200163), Kevin M. Johnson (1310253)   +7 more
core   +1 more source

CASTOR1 Regulates Humoral Immune Responses and Contributes to the Pathogenesis of Systemic Lupus Erythematosus

Arthritis &Rheumatology, EarlyView.
Objective CASTOR1 senses arginine and regulates mammalian target of rapamycin complex 1 (mTORC1), a central metabolic signaling molecule. This study aimed to elucidate the roles of CASTOR1 in humoral immune responses. Methods We analyzed human B cell transcriptomes from healthy controls and patients with systemic lupus erythematosus (SLE) via ...
Takeshi Kusuda, Toshihiko Komai, Takahiro Itamiya, Tatsuki Abe, Tomohisa Okamura, Keishi Fujio   +5 more
wiley   +1 more source

Identification of Potential Drug Targets for the Treatment of Severe Burn Wounds from a Multi-Omics Perspective

Journal of Inflammation Research
Gehua Zhu,1,* Jiaqi Li,2,* Jiamin Xu,1 Guanghua Guo,1 Feng Zhu2 1Medical Centre of Burn Plastic and Wound Repair, The First Affiliated Hospital, Jiangxi Medical College, Nanchang University, Nanchang, People’s Republic of China; 2Department of ...
Zhu G, Li J, Xu J, Guo G, Zhu F
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