Results 101 to 110 of about 47,201 (334)
Immunosuppressive effect and global dysregulation of blood transcriptome in response to psychosocial stress in vervet monkeys (Chlorocebus sabaeus). [PDF]
, 2020 Psychosocial stressors - life events that challenge social support and relationships - represent powerful risk factors for human disease; included amongst these events are relocation, isolation and displacement.
Benjamin, Cassandra +8 more
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Predicting cervical cancer DNA methylation from genetic data using multivariate CMMP
Canadian Journal of Statistics, EarlyView.Abstract Epigenetic modifications link the environment to gene expression and play a crucial role in tumour development. DNA methylation, in particular, is gaining attention in cancer research, including cervical cancer, the focus of this study.
Hang Zhang +5 more
wiley +1 more source
Epilepsia, EarlyView.Abstract Objective Drug‐resistant epilepsy (DRE) affects approximately one‐third of patients with epilepsy. The molecular heterogeneity underlying DRE remains poorly defined, largely due to limited access to resected brain tissue and substantial genetic diversity.
Yanping Weng +11 more
wiley +1 more source
Comparison of Clustering Methods for Time Course Genomic Data: Applications to Aging Effects
, 2014 Time course microarray data provide insight about dynamic biological processes. While several clustering methods have been proposed for the analysis of these data structures, comparison and selection of appropriate clustering methods are seldom discussed.
Horvath, Steve +3 more
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K-Module Algorithm: An Additional Step to Improve the Clustering Results of WGCNA Co-Expression Networks [PDF]
, 2021 Jie Hou +3 more
openalex +1 more source
International Journal of Cancer, EarlyView.What's New? Unraveling the networks that regulate androgen receptor (AR) function is critical to better understanding prostate cancer development and progression. Of particular interest in this regard is the long non‐coding RNA PVT1, which regulates gene expression in cancer and is upregulated in prostate tumors.
Maria Gabriela Berzoti‐Coelho +7 more
wiley +1 more source
Identification the role of necroptosis in rheumatoid arthritis by WGCNA network
AutoimmunityRheumatoid arthritis (RA) is the predominant manifestation of inflammatory arthritis, distinguished by an increasing burden of morbidity and mortality. The intricate interplay of genes and signalling pathways involved in synovial inflammation in patients with RA remains inadequately comprehended. This study aimed to ascertain the role of necroptosis in
Feige Nian +3 more
openaire +3 more sources
iMetaOmics, EarlyView.The “efficacy paradox” of phytochemicals, low bioavailability yet significant health benefits, is associated with gut microbiota, which biotransforms dietary precursors into bioactive metabolites, enabling systemic effects. Thus, health outcomes of diet depend not just on intake “the rainbow”, but on gut microbial metabolism, redefining “you are what ...
Peng Yang, Ren‐You Gan
wiley +1 more source
Colon cancer recurrence-associated genes revealed by WGCNA co-expression network analysis
Molecular Medicine Reports, 2017 The present study aimed to identify the recurrence‑associated genes in colon cancer, which may provide theoretical evidence for the development of novel methods to prevent tumor recurrence. Colon cancer and matched normal samples microarray data (E‑GEOD‑39582) were downloaded from ArrayExpress. Genes with significant variation were identified, followed
Zhai, Xiaofeng +4 more
openaire +3 more sources
Gut microbial features can predict host phenotype response to protein deficiency. [PDF]
, 2018 Malnutrition remains a major health problem in low- and middle-income countries. During low protein intake, <0.67 g/kg/day, there is a loss of nitrogen (N2 ) balance, due to the unavailability of amino acid for metabolism and unbalanced protein ...
Dugas, Lara R +5 more
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