Results 121 to 130 of about 47,201 (334)

Transcriptome and WGCNA reveal hub genes in sugarcane tiller seedlings in response to drought stress [PDF]

open access: gold, 2023
Yuwei Tang   +7 more
openalex   +1 more source

Omics Insights Into the Effects of Highbush Blueberry and Cranberry Crop Agroecosystems on Honey Bee Health and Physiology

open access: yesPROTEOMICS, EarlyView.
ABSTRACT Honey bees (Apis mellifera) are vital pollinators in fruit‐producing agroecosystems like highbush blueberry (HBB) and cranberry (CRA). However, their health is threatened by multiple interacting stressors, including pesticides, pathogens, and nutritional changes.
Huan Zhong   +25 more
wiley   +1 more source

Uric Acid in Metabolic Dysfunction‐Associated Steatotic Liver Disease

open access: yesPortal Hypertension &Cirrhosis, EarlyView.
MASLD is the most prevalent chronic liver disease worldwide, yet effective pharmacological treatments remain limited. Hyperuricemia is now recognized as a key driver of hepatic steatosis, inflammation, and fibrosis, with elevated serum uric acid levels independently predicting hepatocellular carcinoma and liver‐related mortality.
Rong Wang   +5 more
wiley   +1 more source

PTPLAD2 and USP49 Involved in the Pathogenesis of Smoke-Induced COPD by Integrative Bioinformatics Analysis

open access: yesInternational Journal of COPD, 2020
Qiang Zhang,1 Wei Song,1 Nahemuguli Ayidaerhan,2 Zheng He3 1Department of Pulmonary and Critical Care Medicine, Shengjing Hospital of China Medical University, Shenyang, Liaoning Province 110042, People’s Republic of China; 2Department of Pulmonary
Zhang Q, Song W, Ayidaerhan N, He Z
doaj  

Fuzzy Forests: Extending Random Forest Feature Selection for Correlated, High-Dimensional Data

open access: yesJournal of Statistical Software, 2019
In this paper we introduce fuzzy forests, a novel machine learning algorithm for ranking the importance of features in high-dimensional classification and regression problems. Fuzzy forests is specifically designed to provide relatively unbiased rankings
Daniel Conn   +3 more
doaj   +1 more source

RNA‐binding protein RBMS1: A new target for cancer diagnosis and treatment

open access: yesPrecision Medical Sciences, EarlyView.
This schematic illustrates the diverse regulatory roles of RNA‐binding motif single‐stranded interacting protein 1 (RBMS1) across multiple human cancers. In breast cancer, RBMS1 stabilizes B4GALT1 mRNA to promote PD‐L1 glycosylation, modulating tumor immune escape and immunotherapy efficacy.
Xingda Run   +7 more
wiley   +1 more source

Plac8 regulates the fibrogenic ability of cardiac fibroblasts in mice with myocardial infarction

open access: yesAll Life
Cardiac fibroblasts (CFs) are of vital importance for post-myocardial infarction (MI) remodeling. This study explored the role of Placenta specific 8 (Plac8) in MI on the basis of single-cell RNA-Seq (scRNA-Seq) data (GSE136088) and micro-array data ...
Ting Fu   +3 more
doaj   +1 more source

Integrated genomic and transcriptomic approaches reveal oxidative stress adaptation mechanisms in a mesotrione‐resistant Amaranthus tuberculatus biotype

open access: yesPest Management Science, EarlyView.
Integrated GWAS and transcriptomics in a Canadian waterhemp biotype reveal mesotrione resistance is polygenic and metabolically driven. Significant SNPs and 187 herbicide‐responsive genes point to enhanced redox homeostasis, glutathione‐linked detoxification, lipid/secondary metabolism, and oxidative stress responses. Resistance arises from coordinated,
Martin Laforest   +6 more
wiley   +1 more source

Identification of crucial genes through WGCNA in the progression of gastric cancer

open access: yesJournal of Cancer
Background: To explore the hub gene closely related to the progression of gastric cancer (GC), so as to provide a theoretical basis for revealing the therapeutic mechanism of GC. Methods: The gene expression profile and clinical data of GSE15459 in Gene Expression Omnibus (GEO) database were downloaded. The weighted gene co-expression network analysis (
Liu, Rui   +12 more
openaire   +2 more sources

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