Results 141 to 150 of about 43,312 (289)
Screening of m6A-associated ferroptosis-related genes in atherosclerosis based on WGCNA
Frontiers in Cardiovascular MedicineBackgroundN6-methyladenosine (m6A) has been shown to mediate ferroptosis but its role in atherosclerosis (AS) is unclear.MethodsDifferentially expressed m6A-associated ferroptosis-related genes (DE-m6A-Ferr-RGs) were obtained using differential expression analysis and Pearson correlation analysis.
Meiling Jiang +3 more
openaire +3 more sources
Integrative Zoology, EarlyView.Multi‐omics analysis reveals that herbivorous adaptation in Lordiphosa flies arises from coordinated interactions across the genome, transcriptome, and gut microbiota: genomic expansions of detoxification (e.g., cytochrome P450s) and carbohydrate metabolism gene families, transcriptomic upregulation of energy pathways like lipid oxidation and ...
Run Guo +4 more
wiley +1 more source
WGCNA identified 15 modules in our anti-CD3/CD28 stimulated dataset.
, 2015 WGCNA identified 15 modules in our anti-CD3/CD28 stimulated dataset.
Emma M. Quinn (394306) +7 more
core +1 more source
Identification of key proteins in early-onset Alzheimer’s disease based on WGCNA
Frontiers in Aging NeuroscienceIntroductionEarly-onset Alzheimer’s disease (EOAD) is sporadic, highly heterogeneous, and its underlying pathogenic mechanisms remain largely elusive. Proteomics research aims to uncover the biological processes and key proteins involved in disease progression.
Dazhi Li +3 more
openaire +3 more sources
Transcriptomics Unveil Dsx1 as a Critical Regulator in Sexual Dimorphism of Crustaceans
Integrative Zoology, EarlyView.Sexually dimorphic traits are involved in reproductive competition and are shaped by sex‐biased gene expression. This study identifies Dsx1 as a key male‐biased gene in Morinoia aosen and demonstrates through RNA interference that its disruption feminizes male‐specific T3 leg structures.
Yan Tong +8 more
wiley +1 more source
Cancer Management and Research, 2019 Yidan Song,* Yihua Pan,* Jun LiuState Key Laboratory of Oral Diseases, National Clinical Research Center for Oral Diseases, Department of Orthodontics, West China Hospital of Stomatology, Sichuan University, Chengdu, 610041, People’s Republic of ...
Song Y, Pan Y, Liu J
doaj
The lung cancer risk of each sample in GSE7670 by the WGCNA method.
, 2014 The lung cancer risk of each sample in GSE7670 by the WGCNA method.
Xu Jia (187142) +13 more
core +1 more source
Integrative Zoology, EarlyView.A quantum‐enhanced weighted gene co‐expression network analysis framework integrating quantum amplitude amplification is developed to overcome sample size constraints in zoological genomics. This noise‐tolerant analytical strategy enables robust network reconstruction for non‐model species with limited biological replicates.
Seok‐Jin Kang, Hongchul Shin
wiley +1 more source
Screening of key genes related to disulfidptosis in psoriasis based on the analysis of WGCNA
Scientific ReportsPsoriasis features keratinocyte hyperproliferation. This study aimed to identify disulfidptosis-related key genes in psoriasis for potential diagnostic biomarkers or therapeutic targets. Using the GSE30999 dataset, WGCNA was applied to identify key gene modules. GO, KEGG were used for analysis.
Li, Qingshan +4 more
openaire +2 more sources
Integrated Multi‐Omics Analysis Reveals the Genetic Basis of Phenotypic Variation in Tibetan Sheep
Integrative Zoology, EarlyView.SNaPshot‐validated GWAS results demonstrated significant correlations between candidate single nucleotide polymorphisms (SNPs) and body size traits in Tibetan sheep. Concurrently, hematoxylin and eosin staining, alongside muscle fiber analysis, confirmed pronounced morphological differences in muscle tissue between sheep of varying conformation.
Dehui Liu +16 more
wiley +1 more source