Results 161 to 170 of about 33,188 (253)

Identification and Functional Characterization of COPD Molecular Subtypes Based on Oxeiptosis-Related Genes via WGCNA and Machine Learning. [PDF]

Int J Chron Obstruct Pulmon Dis
Chen W, Zhao J, Sun Z, Zhou X, Zhang X, Yan Z.   +5 more
europepmc   +1 more source

Bioinformatics and machine learning-driven discovery of candidate tissue diagnostic markers for endometriosis with experimental verification. [PDF]

Front Endocrinol (Lausanne)
Du J, Zhao S, Feng Q, Cheng W.
europepmc   +1 more source

Role of Macrophage-Related Genes GAS7 and ZEB2 in Acute Myocardial Infarction Pathogenesis. [PDF]

Hum Mutat
Liu Z, Song J, Li L, Fan Z, Xie G, Yang L.   +5 more
europepmc   +1 more source

Integrating Single‐Cell and Spatial Transcriptomes in HGSOC to Decipher the Metastasis‐Associated Biomarkers

iNew Medicine, Volume 2, Issue 2, June 2026.
ABSTRACT High‐grade serous ovarian cancer (HGSOC) is the most common and lethal histological subtype of ovarian cancer. This study aimed to identify peritoneal metastasis‐associated biomarkers of HGSOC to provide directions for subsequent treatment. Transcriptome data were extracted from the GEO database and literature. Differential expression analysis,
Jing Zhu, Zhicheng Yu, Yang Zhang, Hui Hong, Xiaoli Wang, Shan Jiang, Ying Zhou, Cheng Peng, Hongbo Chen   +8 more
wiley   +1 more source

Identification of candidate biomarkers for NAFLD through bioinformatics analysis and machine learning based on circulating insulin degradation-associated genes. [PDF]

Front Endocrinol (Lausanne)
Guo M, Lou W, Song X, Gao D, Wang G, Ma H, Wang W, Wang Y.   +7 more
europepmc   +1 more source

Chronic Low‐Dose Unsymmetrical Dimethylhydrazine Exposure in Rats: Multiorgan Mechanisms and Biomarker Identification

Journal of Applied Toxicology, Volume 46, Issue 6, Page 1987-2002, June 2026.
ABSTRACT Unsymmetrical dimethylhydrazine (UDMH), a highly toxic rocket propellant with known multiorgan effects, requires urgent characterization of its chronic low‐dose toxicity. Using an integrated approach including exploratory transcriptomics (n = 3/group) and metabolomic (n = 4/group) approaches in male Sprague–Dawley rats exposed to high‐dose ...
Fuzhou Liu, Bing Liu, Keli Wang, Xiaoyu Wang, Zhen Sun, Xiaojuan Pan, Zengming Zhao   +6 more
wiley   +1 more source

ENOX2 and the related mechanisms as potential genetic targets for varicose veins of lower extremities: An integrated bioinformatics and Mendelian analysis. [PDF]

Medicine (Baltimore)
He Q, Zhang X, Tao C, Chen C, Yan W.
europepmc   +1 more source

Multi‐Omics and Machine Learning Integration Identifies Key Endothelial Modules in Carotid Artery Stenosis

Journal of Clinical Laboratory Analysis, Volume 40, Issue 11, June 2026.
This study integrates multi‐omics data (single‐cell RNA‐seq, bulk RNA‐seq, and proteomics) from carotid artery plaques to identify novel biomarkers for diagnosing stenosis. Through a computational pipeline involving cell population analysis, WGCNA, and machine learning models, we identified and validated NRP1 and XAF1 as key endothelial biomarkers ...
Jiayi Wu, Chunguang Guo, Linfeng Zhang, Gaopo Cai, Yi Liu, Kai Tang   +5 more
wiley   +1 more source

Identification of Key Genes Associated with Feed Utilization Efficiency in <i>Penaeus vannamei</i> Fed a Plant-Based Diet Using WGCNA. [PDF]

Animals (Basel)
Zhang H, Xu Y, Sui J, Fu Q, Liu M, Tan J, Kong J, Luo K, Meng X, Luan S, Dai P.   +10 more
europepmc   +1 more source

Host–Pathogen Dual Targeting With Repurposed Drugs Identifies a Synergistic Therapy for Intracellular Staphylococcus aureus

MicrobiologyOpen, Volume 15, Issue 3, June 2026.
A large intracellular drug‐repurposing screen identifies a potent synergy between 5‐fluoro‐2′‐deoxycytidine and rifapentine, acting through dual host–pathogen targeting to reduce Staphylococcus aureus burdens across strains, cell types, and infection models (created with BioRender).
Blanca Lorente‐Torres, Helena Á. Ferrero, Pablo Castañera, Jesús Llano‐Verdeja, Sergio Fernández‐Martínez, Amanda Herrero‐González, Farzaneh Javadimarand, Roberto López, Jesús F. Aparicio, Andrew M. Edwards, Volker Behrends, Luis M. Mateos, Álvaro Mourenza, Michal Letek   +13 more
wiley   +1 more source