Results 161 to 170 of about 47,201 (334)

Nasal Airway Transcriptome Reflects Selected Asthma‐Associated Gene Signatures in the Lower Airways

Allergy, EarlyView.
Seven genes and two gene modules were consistently associated with asthma in both airway compartments in ARMS and were validated in ATLANTIS. The two modules reflected IL‐13 related inflammation and mast cell activity, respectively. Nasal gene signatures provide a non‐invasive proxy for selected bronchial asthma‐associated gene signatures. ARMS, Asthma
Hui Wen, Tessa Kole, Orestes A. Carpaij, Tatiana Karp, Victor Guryev, Alen Faiz, Kian Fan Chung, Pankaj Bhavsar, Ian M. Adcock, Salman Siddiqui, Andy Lan, Katie L. Raby, Nazanin Zounemat‐Kermani, Chris Brightling, Dave Singh, Janwillem Kocks, Monica Kraft, Bianca Beghé, Klaus F. Rabe, Alberto Papi, Machteld N. Hylkema, Martijn C. Nawijn, Maarten van den Berge   +22 more
wiley   +1 more source

Integrated Analysis Reveals COL4A3 as a Novel Diagnostic and Therapeutic Target in UV-Related Skin Cutaneous Melanoma

Clinical, Cosmetic and Investigational Dermatology
Zuochao Yao, Lu Lu, Qianhui Xu, Shan Hua, Hui Wang, Hua Jiang Department of Plastic and Reconstructive Surgery, Shanghai East Hospital, School of Medicine, Tongji University, Shanghai, 200092, People’s Republic of ChinaCorrespondence: Hui Wang; Hua Jiang,
Yao Z, Lu L, Xu Q, Hua S, Wang H, Jiang H   +5 more
doaj  

Identification of a 5-Gene-Based Scoring System by WGCNA and LASSO to Predict Prognosis for Rectal Cancer Patients [PDF]

, 2021
He Huang, Shilei Xu, Aidong Chen, Fen Li, Jiezhong Wu, Xusheng Tu, Kunpeng Hu   +6 more
openalex   +1 more source

Identification of prognostic biomarkers in neuroblastoma using WGCNA and multi-omics analysis

Discover Oncology
Neuroblastoma (NB) is one of the most frequent parenchymal tumors among children, with a high degree of heterogeneity and wide variation in clinical presentation. Despite significant therapeutic advances in recent years, long-term survival in high-risk patients remains low, emphasizing the urgent need to find new biomarkers and construct reliable ...
Yuhan Ke, Wenliang Ge
openaire   +3 more sources

Retracted: High-Throughput Screen of Natural Compounds and Biomarkers for NSCLC Treatment by Differential Expression and Weighted Gene Coexpression Network Analysis (WGCNA) [PDF]

BioMed Research International
openalex   +1 more source

Combining WGCNA and machine learning to construct immune-related EMT patterns to predict HCC prognosis and immune microenvironment [PDF]

, 2023
Yating Sun, Shengfu He, Mingyang Tang, Ding Zhang, Bao Meng, Jiawen Yu, Yanyan Liu, Jiabin Li   +7 more
openalex   +1 more source

Optic nerve sheath meningioma exhibits neural niche‐associated transcriptomic features and rare copy number variation‐linked evolution

Brain Pathology, EarlyView.
Optic nerve sheath meningiomas are typically NF2‐intact with few copy number alterations and are generally clinically indolent. Rare aggressive recurrences are associated with progressive accumulation of copy number variations, including CDKN2A/B homozygous deletion, 1q gain, and 14q loss.
Daisuke Sato, Satoru Miyawaki, Yu Sakai, Kenta Ohara, Yu Teranishi, Yudai Hirano, Motoyuki Umekawa, Takahiro Tsuchiya, Shotaro Ogawa, So Hirata, Hiroki Hongo, Hideaki Ono, Daisuke Komura, Tetsuo Ushiku, Shumpei Ishikawa, Nobuhito Saito   +15 more
wiley   +1 more source

Module Preservation Across Breast Cancer RNA-seq Data Using WGCNA

, 2017
Breast cancer is the most common cancer in US, 61,000 new cases are expected to be diagnoised in 2016. Even though a list of differentially expressed genes and frequently mutated genes have been identified, the differential co-expression network and the module preservation between normal breast tissue and early stage in breast carcinogenesis haven’t ...
openaire   +1 more source

Integrative bioinformatics analysis reveals STAT2 as a novel biomarker of inflammation-related cardiac dysfunction in atrial fibrillation

Open Medicine, 2023
Li Cairong, Li Guanhua, Tu Sijia, Bai Xinghua, Yuan Hong   +4 more
doaj   +1 more source

Identification of Characteristic Genes in Whole Blood of Intervertebral Disc Degeneration Patients by Weighted Gene Coexpression Network Analysis (WGCNA) [PDF]

, 2022
Xiaobo Ma, Junqiang Su, Bo Wang, Xiasheng Jin   +3 more
openalex   +1 more source