Results 111 to 120 of about 33,188 (253)

Weighted Gene Co-Expression Network Analysis (WGCNA) in chorioallantois.

open access: yes, 2019
Correlation (r) of each module identified by WGCNA to external factors (Gestation and fetal gender). Color and depth of color corresponds to depth of correlation, with positive correlation indicated in red, negative correlation indicated in blue ...
Pouya Dini (6109472)   +4 more
core   +1 more source

Proteomic profile of CSF obtained at the time of diagnosis determines amyotrophic lateral sclerosis progression and survival: CXCL7 levels in disease prognosis and survival

open access: yesBrain Pathology, EarlyView.
Untargeted multiomic profiling of cerebrospinal fluid reveals that proteomic, but not lipidomic, signatures robustly distinguish ALS patients from controls and stratify individuals by survival, highlighting marked molecular differences between short survival and long survival disease.
Sergio Roca‐Pereira   +19 more
wiley   +1 more source

Construction of mRNAsi related module genes using WGCNA.

open access: yes
(A) Analysis of scale-free exponent and average connectivity of various soft threshold powers; (B) Cluster dendrogram of the co-expression network modules; (C) Module thresholds for WGCNA analysis; (D) The number of genes in each module. (PDF)
Lixia Liu (447585)   +12 more
core   +1 more source

Screening of key genes related to disulfidptosis in psoriasis based on the analysis of WGCNA

open access: yesScientific Reports
Psoriasis features keratinocyte hyperproliferation. This study aimed to identify disulfidptosis-related key genes in psoriasis for potential diagnostic biomarkers or therapeutic targets. Using the GSE30999 dataset, WGCNA was applied to identify key gene modules. GO, KEGG were used for analysis.
Li, Qingshan   +4 more
openaire   +2 more sources

Impact of G‐CSF on Donor TCR Clonal Diversity and T Cell Function During Donor HSC Mobilisation

open access: yesCell Proliferation, EarlyView.
In this study, we found that G‐CSF mobilisation caused a reduction in TCR clonal diversity and down‐regulation of T‐cell function in donors. This may be one of the reasons for the low incidence of GVHD mediated by G‐CSF after allo‐HSCT. Source: Created in BioRender. Li https://BioRender.com/otownki.
Xinye Li   +14 more
wiley   +1 more source

Network topological properties of regulatory networks inferred using RulNet, WGCNA and Pearson methods.

open access: yes, 2015
Network topological properties of regulatory networks inferred using RulNet, WGCNA and Pearson methods.
Pierre Martre (159412)   +6 more
core   +1 more source

Genomic variation drives plant flavor diversification

open access: yesJournal of Integrative Plant Biology, EarlyView.
This review explains how genomic variation shapes plant flavor by altering the biosynthetic and regulatory pathways of key attributes like sweetness, acidity, bitterness, piquancy, astringency, and aroma. It also discusses how multi‐omics, AI‐assisted breeding, and gene editing can translate this knowledge into plants with improved flavor, nutrition ...
Huimin Hu   +5 more
wiley   +1 more source

WGCNA and ferroptosis genes in OSCC: unraveling prognostic biomarkers and therapeutic targets

open access: yesDiscover Oncology
Oral squamous cell carcinoma (OSCC) is the predominant type of oral cancer, with over 370,000 new cases and approximately 170,000 deaths annually worldwide. Despite therapeutic advancements, OSCC mortality rates have been increasing, underscoring the need for improved prognostic models and therapeutic targets.We integrated transcriptomic and clinical ...
Ke Liu   +4 more
openaire   +3 more sources

High‐quality genome of elite peanut cultivar ZH05 reveals subgenome asymmetry, pan‐genome diversity, and breeding insights

open access: yesJournal of Integrative Plant Biology, EarlyView.
A high‐quality reference genome for the elite peanut cultivar Zhonghua No. 5 revealed differing evolutionary paths between the two peanut subgenomes. SubA has higher overall gene expression and more open chromatin, whereas SubB has stronger structural organization, higher DNA methylation, and greater adaptive diversity associated with peanut evolution ...
Taihua Yang   +19 more
wiley   +1 more source

Ectopic Expression of ScALDH21 From a Desert Moss Enhances Cotton Resistance to Verticillium Wilt via the Modulation of Jasmonates and Phenylpropanoid Pathways

open access: yesPlant Biotechnology Journal, EarlyView.
ABSTRACT Biotic stresses, particularly Verticillium wilt (VW), lead to a global decline in cotton yields. Here, we demonstrate that ectopic expression of ScALDH21, a gene from the desiccation‐tolerant moss Syntrichia caninervis Mitt. and absent in angiosperms, enhances cotton's resistance to VW.
Honglan Yang   +13 more
wiley   +1 more source

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