Results 81 to 90 of about 43,312 (289)

Deciphering The Links Between Non-Alcoholic Fatty Liver and Hepatocellular Carcinoma Prognosis: A Weighted Gene Co-Expression Network Analysis Approach

Indonesian Journal of Cancer
Background: Metabolic Associated Fatty Liver Disease (MAFLD) is a common liver disease associated with an increased risk of developing hepatocellular carcinoma (HCC).
Mariam Mahmoud Abady, Amal Magdy
doaj   +1 more source

Analysis of Gene Co-Expression Network to Identify the Role of CD8 + T Cell Infiltration-Related Biomarkers in High-Grade Glioma

International Journal of General Medicine, 2022
Peng Feng,1,* Yuchen Li,2,* Zhijie Tian,1,* Yuan Qian,1 Xingyu Miao,1 Yuelin Zhang3 1Neurosurgery, Shaanxi Provincial People’s Hospital, Xian, 710068, People’s Republic of China; 2Hengyang Medical School, University of South China, Hengyang ...
Feng P, Li Y, Tian Z, Qian Y, Miao X, Zhang Y   +5 more
doaj  

WGCNA input. Phenotypic traits of Virginia opossum individuals

, 2018
Tab-delimited text file with phenotypic trait measurements fro 13 Virginia opossum specimens that was used as input for the weighted gene coexpression network analysis (WGCNA). The traits that were used in the WGCNA analysis were PTP (proportion of tail
Sergio Nigenda-Morales (5118326), Nigenda-Morales, Sergio   +1 more
core   +1 more source

Identification of thyroid cancer biomarkers using WGCNA and machine learning

European Journal of Medical Research
The incidence of thyroid cancer (TC) is increasing in China, largely due to overdiagnosis from widespread screening and improved ultrasound technology. Identifying precise TC biomarkers is crucial for accurate diagnosis and effective treatment.TC patient data were obtained from TCGA.
Gaofeng Hu, Wenyuan Niu, Jiaming Ge, Jie Xuan, Yanyang Liu, Mengjia Li, Huize Shen, Shang Ma, Yuanqiang Li, Qinglin Li   +9 more
openaire   +3 more sources

Oral Recombinant Human Collagen III Protects Gastric Mucosa via G‐Quadruplex‐Mediated Activation of the Pla2g4a‐Prostaglandin Axis

Advanced Science, EarlyView.
Orally administered recombinant human type III collagen protects the gastric mucosa from ethanol‐induced injury by coordinating redox homeostasis, epithelial barrier repair, and arachidonic acid–prostaglandin metabolism. Gastric digestion releases the pentapeptide GPAEF, which interacts with the Pla2g4a promoter G‐quadruplex in a structure‐dependent ...
Xinyue Lan, Qiu Dai, Yanhui Wang, Jiaxuan Gu, Chengyun Wang, Weicheng Xu, Xinru Gao, Jiageng Cheng, Wentao Geng, Xiaowen Wu, Haihang Li, Xiaoyun He, Shengwei Fu, Longjiao Zhu, Wentao Xu   +14 more
wiley   +1 more source

Stage-specific Genetic Studies of Breast Cancer Based on Multi-omics Data

Taiyuan Ligong Daxue xuebao
【Purposes】 Precisely identifying key genes at different stages of cancer and understanding their biological functions are essential for a deeper understanding of cancer pathogenesis.
QIAO Jiao, AN Meiwen, JIAO Xiong
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WGCNA identification of key gene modules.

(A) soft threshold of WGCNA; (B) average connectivity of WGCNA; (C) cluster dendrogram of WGCNA; (D) key gene module map of WGCNA; (E) MEturquoise module genes intersected with DEGs taken.
Liu Wang (213066), Shizhang Zhan (18120962), Ruoran Li (11652139), Wenping Wang (440405)   +3 more
core   +1 more source

Samples and traits for WGCNA

, 2015
Table of traits for samples for network analysis with the R package WGCNA. Rows are samples. Columns are traits. Values are binary indicators of whether the sample is positive for that trait. Traits are AL, H, and D for the three disease states (ahead of
Mikhail V. Matz (51701), Wright, Rachel M., Aglyamova, Galina V., Matz, Mikhail V., Galina V. Aglyamova (3245331), Eli Meyer (248745), Rachel M. Wright (447448), Meyer, Eli   +7 more
core   +1 more source

Single‐Cell Transcriptomic Profiling Identifies B Cell‐Intrinsic Dysregulation of Sphingolipid Biosynthesis and Could Be Improved by Inhibiting UGCG in Primary Immune Thrombocytopenia

Advanced Science, EarlyView.
This study generates the single‐cell atlas of pathogenic B‐cell subset Bc‐5 in ITP. It identifies RUNX3 as a key survival regulator and uncovers sphingolipid‐driven metabolic reprogramming, validating UGCG inhibition as a therapeutic candidate and building a valuable resource for ITP mechanistic and therapeutic exploration.
Dongmei Luo, Yanxia Zhan, Lili Ji, Pengcheng Xu, Pu Chen, Hao Pang, Yunan Ling, Fanli Hua, Xibing Zhuang, Hao Chen, Yunfeng Cheng   +10 more
wiley   +1 more source

Super-Enhancer-Associated Hub Genes In Chronic Myeloid Leukemia Identified Using Weighted Gene Co-Expression Network Analysis

Cancer Management and Research, 2019
Hongying Ma,1,2 Jian Qu,3 Jian Luo,1,2 Tingting Qi,3 Huanmiao Tan,4 Zhaohui Jiang,1 Haiwen Zhang,1 Qiang Qu1,2 1Department of Pharmacy, Xiangya Hospital, Central South University, Changsha 410008, Hunan, People’s Republic of China; 2Institute for ...
Ma H, Qu J, Luo J, Qi T, Tan H, Jiang Z, Zhang H, Qu Q   +7 more
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