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Vitreoretinal Interface Changes in Geographic Atrophy
Geographic atrophy (GA) is the end-stage manifestation of atrophic age-related macular degeneration (AMD). The disease progresses slowly over time, eventually causing loss of central vision. Its cause and pathomechanism are not fully known. Previous studies have suggested that vitreoretinal traction (VRT) may contribute to the progression of ...
Abdillahi, Hannan +4 more
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PURPOSE The Geographic Atrophy Progression (GAP) study was designed to assess the rate of geographic atrophy (GA) progression and to identify prognostic factors by measuring the enlargement of the atrophic lesions using fundus autofluorescence (FAF ...
Steffen Schmitz-Valckenberg +2 more
exaly +2 more sources
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Identifying geographic atrophy
Current Opinion in Ophthalmology, 2023Purpose of review Age-related macular degeneration (AMD) is one of the leading causes of blindness and can progress to geographic atrophy (GA) in late stages of disease. This review article highlights recent literature which assists in the accurate and timely identification of GA, and monitoring of GA progression.
Leanne, Clevenger +1 more
openaire +2 more sources
[Imaging diagostics of geographic atrophy]
Der Ophthalmologe : Zeitschrift der Deutschen Ophthalmologischen Gesellschaft, 2011The development of imaging technologies has contributed to the understanding of the genesis and pathophysiological mechanisms of geographic atrophy (GA) secondary to age-related macular degeneration (AMD). Fundus autofluorescence (FAF) imaging allows accurate discrimination of the boundaries of atrophic patches.
M, Fleckenstein +5 more
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Genetic and molecular biomarkers for geographic atrophy
Acta Ophthalmologica, 2023AbstractGeographic atrophy (GA) is characterized by atrophy of the retina, retinal pigment epithelium and choriocapillaris, causing a gradual loss of vision over time. Treatment options to prevent initiation or progression of GA are limited; two recently FDA‐approved inhibitors of the complement system (pegcetacoplan, avacincaptad pegol) showed a ...
Bridget Riley‐Gillis +3 more
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Characterisation of macular neovascularisation in geographic atrophy
British Journal of Ophthalmology, 2021AimTo characterise macular neovascularisation (MNV) developing in eyes affected by geographic atrophy (GA).MethodsIn this multicentric longitudinal study involving three retina referral centres, patients previously affected by GA who developed an active MNV were included.
Riccardo Sacconi +10 more
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Geographic Chorioretinal Atrophy in Pseudoxanthoma Elasticum
American Journal of Ophthalmology, 2013To describe a series of patients with geographic atrophy independent of choroidal neovascularization (CNV) in pseudoxanthoma elasticum and to report progression over time.Retrospective observational case series.Records of all Vanderbilt Eye Institute patients with pseudoxanthoma elasticum and at least 1 set of color fundus photographs were reviewed (41
Scott D, Schoenberger, Anita, Agarwal
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Therapies for Geographic Atrophy
International Ophthalmology Clinics, 2023Suzie A, Gasparian +2 more
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