Results 31 to 40 of about 85,700 (265)
Modelling stem cell differentiation related processes—A practical overview for biologists
FEBS Letters, EarlyView.Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar +4 more
wiley +1 more source
A Method for Reducing the Impact of Range Ambiguity
Leida xuebao, 2017 In this paper, we study the clutter suppression problem of an airborne bistatic radar with range ambiguity and propose a novel method to reduce the impact of range ambiguity using geometric configuration.
Wei Min, Li Xiaobo, Wang Li
doaj +1 more source
IEEE Journal of Selected Topics in Applied Earth Observations and Remote Sensing, 2021 Spaceborne-airborne multistatic synthetic aperture radar (SA-MuSAR) has the ability to provide high-resolution forward-looking imagery for receivers, but it relies on careful design of the geometric configuration (GC).
Deqing Mao +6 more
doaj +1 more source
Reconstructing enzyme evolution by protein engineering
FEBS Letters, EarlyView.Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source
Investigating transcription factor dynamics in health and disease using FRAP
FEBS Letters, EarlyView.FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj +3 more
wiley +1 more source
Ìнформаційні технології в освіті, 2013 The paper considers some problems and technologies of teaching geometry using dynamic geometry environments to students of advanced classes and specialized study of mathematics. The author emphasizes the urgency of creating computer-oriented technologies
O.P. Zeleniak
doaj
Molecular Oncology, EarlyView.BCL9 and BCL9L drive bladder cancer progression by enhancing β‐catenin signaling, promoting proliferation, migration, invasion, and organoid growth. Genetic depletion of BCL9(L) suppresses malignant phenotypes, while pharmacological disruption of the β‐catenin/BCL9(L) complex with ZW4864 inhibits canonical Wnt signaling and tumor‐associated cellular ...
Roland Kotolloshi +11 more
wiley +1 more source
A Comprehensive Analysis of Thermal Heat Dissipation for Lithium-Ion Battery Packs
EnergiesEffective thermal management is essential for the safe and efficient operation of lithium-ion battery packs, particularly in compact, airflow-sensitive applications such as drones. This study presents a comprehensive thermal analysis of a 16-cell lithium-
Xuguang Zhang +7 more
doaj +1 more source
Molecular Oncology, EarlyView.Arginine methylation can be viewed as a persistence‐prone post‐translational modification regulated by a network of PRMTs. Competitive and compensatory interactions among PRMTs can redistribute methylation across substrate pools shaped by sequence, structural, spatial, and environmental layers, reinforcing RNA‐processing, chromatin, and signaling ...
So Hyun Kwon, Ji Min Lee
wiley +1 more source
Finding an Optimal Geometric Configuration for TDOA Location Systems With Reinforcement Learning
IEEE Access, 2021 In TDOA passive location tasks, the geometric configuration can greatly affect the positioning precision due to the complicated characteristics of electromagnetic environment.
Shengxiang Li +4 more
doaj +1 more source