Results 51 to 60 of about 85,700 (265)

The crystal structure of the Borrelia burgdorferi nicotinamidase BBE22 resolves a long‐standing annotation error

open access: yesFEBS Open Bio, EarlyView.
The crystal structure of Borrelia burgdorferi nicotinamidase (PncA/BBE22) reveals the correct full‐length protein initiated from a non‐canonical AUU start codon. The structure validates previous biochemical findings and resolves a long‐standing annotation error, demonstrating that the truncated database sequence is structurally incompatible with the ...
Kalvis Brangulis
wiley   +1 more source

Geometric Configuration in Robot Kinematic Design [PDF]

open access: yes, 2008
A lattice of geometries is presented and compared for representing some geometrical aspects of the kinematic design of robot systems and subsystems. Three geometries (set theory, topology and projective geometry) are briefly explored in more detail in the context of three geometric configurations in robotics (robot groupings, robot connectivities and ...
openaire   +1 more source

A new flow chip in combination with multiphoton microscopy as a protocol for longitudinal 3D imaging of tissue calcification under shear stress

open access: yesFEBS Open Bio, EarlyView.
Miniaturized flow chip platform enabling continuous perfusion and longitudinal multiphoton 3D imaging of vascular smooth muscle cell constructs under physiological flow. Brightfield imaging guides region selection, while CellTracker Green and mRuby‐labeled fetuin‐A visualize cells and mineral deposition, respectively. Magnesium supplementation markedly
Vytautas Kučikas   +6 more
wiley   +1 more source

Geometrical sets with forbidden configurations

open access: yesForum of Mathematics, Sigma, 2023
Abstract Given finite configurations $P_1, \dots , P_n \subset \mathbb {R}^d$ , let us denote by $\mathbf {m}_{\mathbb {R}^d}(P_1, \dots , P_n)$ the maximum density a set $A \subseteq \mathbb {R}^d$ can have without containing congruent copies of any
openaire   +4 more sources

Optimizing photoexcitation conditions for time‐resolved X‐ray solution scattering experiments

open access: yesFEBS Open Bio, EarlyView.
Time‐resolved X‐ray solution scattering (TR‐XSS) is a powerful technique to visualize how proteins change their structure in real time after light activation. Selecting the right laser photoexcitation conditions—fluence, excitation geometry, and sample refresh rate—is critical to maximize the experimental signal while avoiding unwanted side effects ...
Matteo Levantino
wiley   +1 more source

GelMA‐based 3D spheroids recapitulate transcriptomic and functional hallmarks of myeloid sarcoma

open access: yesFEBS Open Bio, EarlyView.
GelMA 5% hydrogels support the formation of myeloid leukemia spheroids that recapitulate MS‐specific features, including G1 arrest, apoptosis, and ECM‐driven transcriptomic reprogramming. The 3D model mimicked soft‐tissue‐like stiffness and oxygen conditions, and transcriptomic convergence with primary MS samples confirmed its utility as a preclinical ...
Nicolas Germain   +11 more
wiley   +1 more source

Analysis of second order effects: case study

open access: yesRevista IBRACON de Estruturas e Materiais
This paper presents a nonlinear static analysis of a reinforced concrete plane frame. It has as main objective is to realize a global stability verification of a plane frame, by using geometric stiffness matrix.
J. R. BUENO, D. D. LORIGGIO
doaj   +1 more source

Dependence of observables in elastic scattering of intermediate energy protons by 6He from its structure [PDF]

open access: yesЯдерна фізика та енергетика, 2007
In the framework of variation calculations on the basis of resonating group method with exact consideration of the Pauli principle the most probable geometric configuration of the ground state 6He nucleus (two-neutron α – 2n and linear three-cluster n ...
V. P. Mikhailyuk, Yu. A. Pozdnyakov
doaj  

Structural and biochemical insights into the thermostable esterase Ta0887 from Thermoplasma acidophilum

open access: yesFEBS Open Bio, EarlyView.
In this study, a novel esterase from the thermoacidophilic archaeon Thermoplasma acidophilum was biochemically and structurally characterized. Our results demonstrate that Ta0887 is a highly thermostable esterase that preferentially hydrolyzes p‐nitrophenyl hexanoate and possesses an α‐helical cap domain that likely contributes to its substrate ...
Alejandro Delgado‐Rey   +4 more
wiley   +1 more source

On geometric trilateral-free (n_3) configurations

open access: yesArs Mathematica Contemporanea, 2012
This note presents the first known examples of a geometric trilateral-free (23 3 ) configuration and a geometric trilateral-free (27 3 ) configuration. The (27 3 ) configuration is also pentalateral-free.
openaire   +2 more sources

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