Results 51 to 60 of about 85,700 (265)
The crystal structure of Borrelia burgdorferi nicotinamidase (PncA/BBE22) reveals the correct full‐length protein initiated from a non‐canonical AUU start codon. The structure validates previous biochemical findings and resolves a long‐standing annotation error, demonstrating that the truncated database sequence is structurally incompatible with the ...
Kalvis Brangulis
wiley +1 more source
Geometric Configuration in Robot Kinematic Design [PDF]
A lattice of geometries is presented and compared for representing some geometrical aspects of the kinematic design of robot systems and subsystems. Three geometries (set theory, topology and projective geometry) are briefly explored in more detail in the context of three geometric configurations in robotics (robot groupings, robot connectivities and ...
openaire +1 more source
Miniaturized flow chip platform enabling continuous perfusion and longitudinal multiphoton 3D imaging of vascular smooth muscle cell constructs under physiological flow. Brightfield imaging guides region selection, while CellTracker Green and mRuby‐labeled fetuin‐A visualize cells and mineral deposition, respectively. Magnesium supplementation markedly
Vytautas Kučikas +6 more
wiley +1 more source
Geometrical sets with forbidden configurations
Abstract Given finite configurations $P_1, \dots , P_n \subset \mathbb {R}^d$ , let us denote by $\mathbf {m}_{\mathbb {R}^d}(P_1, \dots , P_n)$ the maximum density a set $A \subseteq \mathbb {R}^d$ can have without containing congruent copies of any
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Optimizing photoexcitation conditions for time‐resolved X‐ray solution scattering experiments
Time‐resolved X‐ray solution scattering (TR‐XSS) is a powerful technique to visualize how proteins change their structure in real time after light activation. Selecting the right laser photoexcitation conditions—fluence, excitation geometry, and sample refresh rate—is critical to maximize the experimental signal while avoiding unwanted side effects ...
Matteo Levantino
wiley +1 more source
GelMA‐based 3D spheroids recapitulate transcriptomic and functional hallmarks of myeloid sarcoma
GelMA 5% hydrogels support the formation of myeloid leukemia spheroids that recapitulate MS‐specific features, including G1 arrest, apoptosis, and ECM‐driven transcriptomic reprogramming. The 3D model mimicked soft‐tissue‐like stiffness and oxygen conditions, and transcriptomic convergence with primary MS samples confirmed its utility as a preclinical ...
Nicolas Germain +11 more
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Analysis of second order effects: case study
This paper presents a nonlinear static analysis of a reinforced concrete plane frame. It has as main objective is to realize a global stability verification of a plane frame, by using geometric stiffness matrix.
J. R. BUENO, D. D. LORIGGIO
doaj +1 more source
Dependence of observables in elastic scattering of intermediate energy protons by 6He from its structure [PDF]
In the framework of variation calculations on the basis of resonating group method with exact consideration of the Pauli principle the most probable geometric configuration of the ground state 6He nucleus (two-neutron α – 2n and linear three-cluster n ...
V. P. Mikhailyuk, Yu. A. Pozdnyakov
doaj
In this study, a novel esterase from the thermoacidophilic archaeon Thermoplasma acidophilum was biochemically and structurally characterized. Our results demonstrate that Ta0887 is a highly thermostable esterase that preferentially hydrolyzes p‐nitrophenyl hexanoate and possesses an α‐helical cap domain that likely contributes to its substrate ...
Alejandro Delgado‐Rey +4 more
wiley +1 more source
On geometric trilateral-free (n_3) configurations
This note presents the first known examples of a geometric trilateral-free (23 3 ) configuration and a geometric trilateral-free (27 3 ) configuration. The (27 3 ) configuration is also pentalateral-free.
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