Results 21 to 30 of about 144,880 (218)

Fuzzy Logic for Incidence Geometry

The Scientific World Journal, 2016
The paper presents a mathematical framework for approximate geometric reasoning with extended objects in the context of Geography, in which all entities and their relationships are described by human language. These entities could be labelled by commonly
Alex Tserkovny
doaj   +1 more source

Geometric equivalence relations on modules

Journal of Pure and Applied Algebra, 1981
In [4] Gersten developed the notion of homotopy for ring homomorphisms. A simple homotopy of two ring homomorphisms f,g : A +B can be viewed as a deformation over the parameter space Spec Z[t]. This is a homomorphism A+B[t] which restricts to f when t = 0 and to g when t = 1.
openaire   +1 more source

Cohomology rings, Rochlin function, linking pairing and the Goussarov--Habiro theory of three--manifolds

, 2003
We prove that two closed oriented 3-manifolds have isomorphic quintuplets (homology, space of spin structures, linking pairing, cohomology rings, Rochlin function) if, and only if, they belong to the same class of a certain surgery equivalence relation ...
Gwénaël Massuyeau, Johnson, Lannes, Matveev, Milnor, Ohtsuki, Turaev   +6 more
core   +3 more sources

Higgs Bundles, Gauge Theories and Quantum Groups [PDF]

, 2006
The appearance of the Bethe Ansatz equation for the Nonlinear Schr\"{o}dinger equation in the equivariant integration over the moduli space of Higgs bundles is revisited. We argue that the wave functions of the corresponding two-dimensional topological U(
A. Gerasimov, A. Gorsky, A.A. Gerasimov, A.Yu. Alekseev, Anton A. Gerasimov, B. Rusakov, C.N. Yang, C.N. Yang, D. Bump, D. Kazhdan, D.J. Gross, D.P. Zelobenko, E. Emsiz, E. Witten, E. Witten, E. Witten, E.H. Lieb, F. Gliozzi, G. Lusztig, G. Lusztig, G. Moore, G.J. Heckman, G.J. Heckman, I. Cherednik, I. Macdonald, I.G. Macdonald, J. Kalkman, K. Gawedzki, K. Hikami, M. Aganagic, M. Atiyah, M. Blau, M. Gaudin, M. Spiegelglas, M.F. Atiyah, M.S. Narashimhan, M.S. Ramanathan, N. Bogoliubov, N.J. Hitchin, P.P. Kulish, S. Cordes, S. Cordes, S. Murakami, Samson L. Shatashvili, T.C. Dunkl, V. Ginzburg, V. Kazakov, V. Kazakov, V.G. Drinfeld, W.D. Neumann   +49 more
core   +2 more sources

A note on degeneracy, marginal stability and extremality of black hole horizons

, 2012
Given a stationary axisymmetric black hole horizon admitting a section characterised as a strictly future stable marginally outer trapped surface, we extend the equivalence between the notions of horizon degeneracy and marginal stability to the ...
Jaramillo, José Luis
core   +1 more source

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

FEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee, Dimitrios Bekiari, Sofia Doello, Karl Forchhammer   +3 more
wiley   +1 more source

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

FEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai, Mizuki Seo, Gyath Karadsheh, Fachrur Rizal Mahendra, Máté Á Demény, Ferenc Győry, János András Mótyán, László Fésüs, Endre Kristóf, Rini Arianti   +9 more
wiley   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

FEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa, Konstantinos Makryniotis, Theofani‐Iosifina Sousani, Evangelos Topakas, Vangelis Daskalakis, Maria Dimarogona   +5 more
wiley   +1 more source

A methionine‐lined active site governs carbocation stabilization and product specificity in a bacterial terpene synthase

FEBS Letters, EarlyView.
This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel, Carl P. O. Helmer, Shani Zev, Ronja Driller, Emily Buhr, Markus Reinbold, Renana Schwartz, Gabriel Foley, Mikael Boden, Daniel Garbe, Gerhard Schenk, Dan Thomas Major, Bernhard Loll, Thomas Brück   +13 more
wiley   +1 more source

Dual targeting of RET and SRC synergizes in RET fusion‐positive cancer cells

Molecular Oncology, EarlyView.
Despite the strong activity of selective RET tyrosine kinase inhibitors (TKIs), resistance of RET fusion‐positive (RET+) lung cancer and thyroid cancer frequently occurs and is mainly driven by RET‐independent bypass mechanisms. Son et al. show that SRC TKIs significantly inhibit PAK and AKT survival signaling and enhance the efficacy of RET TKIs in ...
Juhyeon Son, Lily L. Remsing Rix, Bin Fang, Eric A. Welsh, Nicole V. Bremer, Valentina Foglizzo, Paola Roa, Nickole Sigcha‐Coello, Yi Liao, Eric B. Haura, Alexander Drilon, John M. Koomen, Emiliano Cocco, Uwe Rix   +13 more
wiley   +1 more source