Results 31 to 40 of about 68,847 (256)

A Survey of the Principle and Development of Geometric Function Theory

open access: yesAcademic Science Journal
This article serves as an introduction to the theory of geometric functions. Foundational methodologies and certain advancements within the domain are elucidated with the perspective that the primary audience comprises budding scholars eager to grasp ...
Adnan Aziz Hussein, Kassim A . Jassim
doaj   +1 more source

On the Connection Problem for Painlevé Differential Equation in View of Geometric Function Theory

open access: yesMathematics, 2020
Asymptotic analysis is a branch of mathematical analysis that describes the limiting behavior of the function. This behavior appears when we study the solution of differential equations analytically.
Rabha W. Ibrahim   +2 more
doaj   +1 more source

Studies on a new K-symbol analytic functions generated by a modified K-symbol Riemann-Liouville fractional calculus

open access: yesMethodsX, 2023
Analytic functions are very helpful in many mathematical and scientific uses, such as complex integration, potential theory, and fluid dynamics, due to their geometric features.
Ibtisam Aldawish, Rabha W. Ibrahim
doaj   +1 more source

Modelling stem cell differentiation related processes—A practical overview for biologists

open access: yesFEBS Letters, EarlyView.
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar   +4 more
wiley   +1 more source

Reconstructing enzyme evolution by protein engineering

open access: yesFEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler   +2 more
wiley   +1 more source

Interpreting the effects of DNA polymerase variants at the structural level

open access: yesMolecular Oncology, EarlyView.
Using MAVISp and molecular dynamics simulations, we analyzed over 60 000 missense variants in POLE and POLD1 from ClinVar, COSMIC, cBioPortal, and saturation mutagenesis. Identified mechanistic indicators, including stability, binding, and long‐range, enable structural interpretation, providing ACMG‐like evidence for possible reclassification of VUS ...
Matteo Arnaudi   +7 more
wiley   +1 more source

Geometrical Theory of the Hyperbolic Functions [PDF]

open access: yesProceedings of the Edinburgh Mathematical Society, 1898
1. If PQRS be an Hyperbola, OE, OF its asymptotes, P, Q, R, S any points on it such that the sectorial area OPQ = sectorial area ORS; and if PA, QB, RC, SD be ordinates to one asymptote and parallel to the other, it is known that Hence if A, B, C … be taken so that OA, OB, OC … are in continued proportion, the areas OPQ, OQR, ORS … are all equal,
openaire   +1 more source

ZW4864‐mediated inhibition of the β‐catenin/BCL9/BCL9L complex reveals therapeutic potential in bladder cancer

open access: yesMolecular Oncology, EarlyView.
BCL9 and BCL9L drive bladder cancer progression by enhancing β‐catenin signaling, promoting proliferation, migration, invasion, and organoid growth. Genetic depletion of BCL9(L) suppresses malignant phenotypes, while pharmacological disruption of the β‐catenin/BCL9(L) complex with ZW4864 inhibits canonical Wnt signaling and tumor‐associated cellular ...
Roland Kotolloshi   +11 more
wiley   +1 more source

A geometric problem in function theory

open access: yesIllinois Journal of Mathematics, 2007
The Riemann Mapping Theorem asserts that there is an analytic function in the unit disk taking its boundary values on any given simple smooth curve in the plane. A theorem of Szego says that an analytic function in the disk can have boundary values lying on prescribed circles about the origin.
Helson, Henry, Zabihi, Farhad
openaire   +2 more sources

Analysing the significance of small conformational changes and low occupancy states in serial crystallographic data

open access: yesFEBS Open Bio, EarlyView.
This protocol paper outlines methods to establish the success of a time‐resolved serial crystallographic experiment, by means of statistical analysis of timepoint data in reciprocal space and models in real space. We show how to amplify the signal from excited states to visualise structural changes in successful experiments.
Jake Hill   +4 more
wiley   +1 more source

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