Results 71 to 80 of about 1,144,491 (344)

Leveraging Artificial Intelligence and Large Language Models for Cancer Immunotherapy

Advanced Science, EarlyView.
Cancer immunotherapy faces challenges in predicting treatment responses and understanding resistance mechanisms. Artificial intelligence (AI) and machine learning (ML) offer powerful solutions for cancer immunotherapy in patient stratification, biomarker discovery, treatment strategy optimization, and foundation model development.
Xinchao Wu, Mengtao Sun, Lusheng Li, Jieqiong Wang, Shibiao Wan   +4 more
wiley   +1 more source

Cockroach‐Derived Leucokinin VIII Peptide Accelerates Diabetic Skin Wound Healing by Enhancing Keratinocyte Filopodia Formation

Advanced Science, EarlyView.
This study identifies the cockroach‐derived peptide leucokinin VIII as a potent accelerator of diabetic wound healing. By activating the FAK‐ACTG1 axis, the peptide drives keratinocyte migration and filopodia formation. Delivered via a developed PLGA‐PEG‐PLGA thermosensitive hydrogel for sustained release, this approach significantly hastens wound ...
Zhengshan Qin, Jinchuan Wu, Xiehua Xiao, Xirui Wang, Nianhui Ding, Xin Zhao, Lu Ma, Jie Li, Lunkun Ma, Cehua Ou, Ning Ma, Jianguo Feng   +11 more
wiley   +1 more source

Protein‐Template Gold Nanoclusters Induce Differentiation and Modify the Functional Properties of Primary Astrocytes

Advanced NanoBiomed Research, EarlyView.
The incubation of primary astrocytes with fAuNCs‐BSA induces: (A) long‐term effects including fAuNCs‐BSA internalization, red cell fluorescence, differentiation, upregulation of Ca2+ signaling, Cl‐current, and cell volume regulation. B) Short‐term (200 ms) stimulation with UV LED light increases in Ca2+ signaling and inhibition of K+ current. Astrocyte
Roberta Fabbri, Karima Jeneh Perry, Emanuela Saracino, Chiara Lazzarini, Anna Mariano, Diletta Spennato, Maria Grazia Mola, Maria Grazia Raucci, Alessandro Kovtun, Marianna Barbalinardo, Giorgia Conte, Denis Gentili, Marco Caprini, Vincenzo Palermo, Roberto Zamboni, Luigi Ambrosio, Wolfgang Losert, Andrea Candini, Grazia Paola Nicchia, Raj K. Gupta, Valentina Benfenati, Shashi P. Karna   +21 more
wiley   +1 more source

Procrustean pseudo‐landmark methods in Python to measure massive quantities of leaf shape data

Applications in Plant Sciences, EarlyView.
Abstract Premise When examining leaf shapes that are different from one another, it can be difficult to compare both the overall leaf shape and points along the leaf margin in biologically and statistically meaningful ways. Methods To address this problem, we present a simple and user‐friendly leaf shape analysis method in Jupyter Notebook and Python ...
Asia Hightower, Svea Hall, Ricardo Urquidi Camacho, Alexandra Papamichail, Evan Adamski, Claudia Colligan, Aidan Deneen, Gabriel Dunn, Justine Haziza, Claire Henley, Arnan Pawawongsak, Lachlann Simms, Sean Ward, Manica Balant, Christopher Blackwood, Charles Cannon, Andrea Case, Aman Y. Husbands, Emily B. Josephs, Zoë Migicovsky, Eric Patterson, Yenny Alejandra Saavedra‐Rojas, Daniel H. Chitwood   +22 more
wiley   +1 more source

Finite element analysis of feeding in red and gray squirrels (Sciurus vulgaris and Sciurus carolinensis)

The Anatomical Record, EarlyView.
Abstract Invasive gray squirrels (Sciurus carolinensis) have replaced the native red squirrel (Sciurus vulgaris) across much of Great Britain over the last century. Several factors have been proposed to underlie this replacement, but here we investigated the potential for dietary competition in which gray squirrels have better feeding performance than ...
Philip G. Cox, Peter J. Watson
wiley   +1 more source

The morphology of the oval window in Paranthropus robustus compared to humans and other modern primates

The Anatomical Record, EarlyView.
Abstract The oval window (OW) is an opening connecting the inner and middle ear. Its area has been shown to consistently scale with body mass (BM) in primates, and has been used alongside semi‐circular canal (SCC) size to differentiate Homo sapiens and fossil hominins, including Paranthropus robustus.
Ruy Fernandez, José Braga
wiley   +1 more source

Species classification of Tabanus (Diptera: Tabanidae) in Western Thailand: Integrating DNA barcoding and modern morphometrics

Current Research in Parasitology and Vector-Borne Diseases
The species of Tabanus, commonly known as horse flies, are remarkable ectoparasites capable of transmitting various pathogens to animals and humans. Given their role in disease transmission, accurate identification of horse fly species is critical but ...
Tanasak Changbunjong, Thekhawet Weluwanarak, Sedthapong Laojun, Tanawat Chaiphongpachara   +3 more
doaj   +1 more source

Allometric Changes and Shape Comparisons of Two Southwestern Sucker Species and Their Hybrids Using a Geometric Morphometric Approach [PDF]

, 2022
Pilar N. Wolters‐Rinker, David L. Rogowski, Alice C. Gibb   +2 more
openalex   +1 more source

A perspective from the Mesozoic: Evolutionary changes of the mammalian skull and their influence on feeding efficiency and high‐frequency hearing

The Anatomical Record, EarlyView.
Abstract The complex evolutionary history behind modern mammalian chewing performance and hearing function is a result of several changes in the entire skeletomuscular system of the skull and lower jaw. Lately, exciting multifunctional 3D analytical methods and kinematic simulations of feeding functions in both modern and fossil mammals and their ...
Julia A. Schultz
wiley   +1 more source

Testing the Giles hypothesis using geometric morphometrics

American Journal of Physical Anthropology, 2021
AbstractObjectivesThe Giles hypothesis posits that differences in the cranial morphology of Pan troglodytes and Gorilla gorilla are largely the result of allometric scaling. However, previous support for the Giles hypothesis was based on bivariate plots of linear measurements.
openaire   +3 more sources