Results 91 to 100 of about 42,080 (309)

Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin

open access: yesMolecular Oncology, EarlyView.
The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla   +10 more
wiley   +1 more source

Morphometric characteristics of block streams: A case study of the Vladayska River basin, Vitosha Mountain (Bulgaria) [PDF]

open access: yesJournal of the Bulgarian Geographical Society
Block streams, also known as stone rivers, are common periglacial landforms in the alpine and subalpine zone of the Balkan Peninsula. These features are especially widely spread in the valleys, slopes and summit of Vitosha Mountain.
Petko Bozhkov
doaj   +3 more sources

Using data-driven algorithms for semi-automated geomorphological mapping. [PDF]

open access: yesStoch Environ Res Risk Assess, 2022
Giaccone E   +4 more
europepmc   +1 more source

Geomorphological map of the surroundings of Cortina d’Ampezzo (Dolomites, Italy) [PDF]

open access: yes, 2007
Geomorphological investigations in the area of Cortina d'Ampezzo (Dolomites, Italy) have been carried out since the 1980s mainly within national and European research projects.
SOLDATI, Mauro
core  

Investigating submerged morphologies by means of the low-budget “GeoDive” method (high resolution for detailed 3D reconstruction and related measurements) [PDF]

open access: yes, 2018
Geophysical methods allow to collect geological data on lake and sea bottoms and characterize large areas, even at high depths, but with high costs.
Crognale, Jacopo   +2 more
core   +1 more source

Crucial parameters for precise copy number variation detection in formalin‐fixed paraffin‐embedded solid cancer samples

open access: yesMolecular Oncology, EarlyView.
This study shows that copy number variations (CNVs) can be reliably detected in formalin‐fixed paraffin‐embedded (FFPE) solid cancer samples using ultra‐low‐pass whole‐genome sequencing, provided that key (pre)‐analytical parameters are optimized.
Hanne Goris   +10 more
wiley   +1 more source

Geomorphological mapping of quarries

open access: yesVisnyk of the Lviv University. Series Geography, 2016
Main issues related to the geomorphological mapping of quarries are discussed. The stages of creating these maps are characterized. The first stage is the analysis of raw materials and prefield mapping. The relief in contours with a relatively small value of horizontal crossing (2 m) is depicted in surveying and topographic maps and plans of mines ...
openaire   +2 more sources

Mapping of Potential Show Caves in the Racha Limestone Massif (Country of Georgia) [PDF]

open access: yes, 2018
: The Racha limestone massif is located in the eastern part of the karst zone of western Georgia. The massif is a typical example of Georgian mountain karst regions, where diverse surface and subsurface karst landforms are found.
Asanidze, Lasha   +4 more
core   +1 more source

Evaluation of TanDEM-X DEMs on selected Brazilian sites: comparison with SRTM, ASTER GDEM and ALOS AW3D30

open access: yes, 2018
A first assessment of the TanDEM-X DEMs over Brazilian territory is presented through a comparison with SRTM, ASTER GDEM and ALOS AW3D30 DEMs in seven study areas with distinct geomorphological contexts, vegetation coverage and land use.
Grohmann, Carlos H.
core   +1 more source

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

open access: yesMolecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat   +8 more
wiley   +1 more source

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