Results 91 to 100 of about 1,177,083 (256)
Molecular Oncology, EarlyView.Taxanes are widely used chemotherapeutics whose effects on cellular mechanics remain poorly understood. We show that paclitaxel induces rapid cellular contraction by promoting GEF‐H1 dissociation from microtubules and non‐muscle myosin II activation through RhoA/ROCK.
Gloria Asensio‐Juárez +5 more
wiley +1 more source
Molecular Oncology, EarlyView.Incomplete microwave ablation (iMWA) of liver cancer triggers a biphasic progression in residual tumors. At Day 3, the microenvironment is characterized by acute inflammatory responses and extracellular matrix (ECM) remodeling. By Day 14, a profound shift occurs toward oncogenic signal transduction and immunosuppression, marked by macrophage ...
Yu Liu +9 more
wiley +1 more source
, 1956 Relief shown by spot heights and contours. Contour at 100 ft.; "NMO/56/50"; Also available online http://nla.gov.au/nla.map-vn1758341.
Australia. National Mapping Office.
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Engineering IL‐4 resistant proinflammatory human myeloid cells for cancer immunotherapy
Molecular Oncology, EarlyView.We developed a scalable workflow to generate proinflammatory human myeloid cells. CRISPR/Cas9‐edited CD34+ hematopoietic stem and progenitor cells were expanded and differentiated with M‐CSF. Deletion of STAT6 or STAT6/NFKB1 enhanced macrophage proinflammatory gene expression and cytokine secretion in the presence of IL‐4 while maintaining antibody ...
Theresa Barberi, Alan D. Friedman
wiley +1 more source
Antarctica compared with Australia and the British Isles [cartographic material]
, 1969 Comparative area map of Antarctica, Australia and the British Isles, with images to scale of the British Isles imposed over Australia which is in turn imposed over Antarctica.; Also available online http://nla.gov.au/nla.map-vn4649833; National Library's
Australia. Division of National Mapping.
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Nature and Aims of Geomorphological Mapping
, 2011 Geomorphological maps are amongst the best tools for understanding the physical context of the Earth’s surface. They provide a full objective description of landforms (morphography) identified with specific names and depicted with their correct shape or,
Antonello Cestari +5 more
core +1 more source
Raman‐based label‐free microscopic analysis of the pancreas in living zebrafish larvae
FEBS Open Bio, EarlyView.Forward stimulated Raman scattering (F‐SRS) and epi coherent anti‐Stokes Raman scattering (E‐CARS) allow label‐free discrimination of distinct subcellular structures in the pancreas of living zebrafish larvae. Given the straightforward applicability, we anticipate broad implementation of Raman microscopy in other organs and across various biomedical ...
Noura Faraj +3 more
wiley +1 more source
, 2003 Different starting conditions (active and passive factors) define the various landforms in Umbrian territory. Furthermore in Umbria many lithotypes outcrop, as limestone, sandstones, volcanic bedrock and fluvial-lacustrine sediments, all involved in ...
MELELLI, Laura, Gregori L.
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Geomorphological mapping in urban areas
Journal of Maps, 2021 Pierluigi Brandolini +5 more
doaj +1 more source
Optimizing photoactivation of PA‐mCherry for optical pooled CRISPR screens
FEBS Open Bio, EarlyView.Photoactivatable PA‐mCherry finds widespread use to optically tag individual cells. However, confocal 405 nm UV laser‐scanning (normal scan) is much less efficient than widefield UV illumination, limiting the use of PA‐mCherry on confocal instruments. We remedy this limitation by reporting that rapid and repeated confocal scanning with a low‐intensity,
Sravasti Mukherjee +3 more
wiley +1 more source