Landslides and floods zonation using geomorphological analyses in a dynamic basin of Costa Rica
Despite of the geomorphological diversity of Central America and Costa Rica, there are few detailed geomorphological studies in the region. A 1:25,000 geomorphological analyses of the Upper General River Basin (UGRB) located in the southeast in Costa ...
Adolfo Quesada Román
doaj +1 more source
From mice to humans—divergent strategies for intestinal homeostasis and regeneration
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa +2 more
wiley +1 more source
Modelling stem cell differentiation related processes—A practical overview for biologists
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar +4 more
wiley +1 more source
Mapping Wetland Types in Semiarid Floodplains: A Statistical Learning Approach
Detailed vegetation maps are needed for wetland conservation and restoration as different vegetation communities have distinct water requirements. It is a continuous challenge to map the distribution of different wetland types on a regional scale, and a ...
Megan Powell +5 more
doaj +1 more source
The susceptibility of the Iara Depression to contemporary geomorphological processes [PDF]
Identifying the susceptibility of the land to contemporary geomorphological processes is an essential aspect to be pursued within the proper territorial planning process of the Iara Depression.
G.M. RUS, I.A. IRIMUȘ, S. ROȘCA
doaj +1 more source
Cancer progression is regulated by the dynamic matrix code of the tumor microenvironment, which influences cellular behavior and disease development. Importantly, matrix remodeling in three‐dimensional cancer models more accurately reflects in vivo conditions compared to conventional two‐dimensional systems.
Sylvia Mangani +3 more
wiley +1 more source
Low-cost mapping of coastal geomorphology by remote sensing in Angels Cove, Arraial do Cabo, Brazil
Bathymetry is a crucial information for understanding coastal geomorphological processes. This study aims to evaluate the applicability of Satellite-Derived Bathymetry (SDB) as a low-cost alternative for coastal geomorphological mapping in Angels Cove ...
Ruan Vargas +4 more
doaj +1 more source
Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions
The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang +4 more
wiley +1 more source
Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta +3 more
wiley +1 more source
An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes
GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg +14 more
wiley +1 more source

