Results 61 to 70 of about 4,472 (296)

Spontaneously abandoned settlements in Serbia: Part 2 [PDF]

open access: yesZbornik Radova: Geografski institut "Jovan Cvijić", 2011
This is the second part of the article “Spontaneously abandoned settlements in Serbia”, the first part of which was published in No. 60-2 of this Journal.
Milošević Marko V.   +2 more
doaj   +1 more source

A global geomorphologic map of Saturn’s moon Titan

open access: yesNature Astronomy, 2019
Titan has an active methane-based hydrologic cycle1 that has shaped a complex geologic landscape2, making its surface one of most geologically diverse in the solar system. Despite the different materials, temperatures, and gravity fields between Earth and Titan, many surface features are similar between the two worlds and can be interpreted as products
Lopes, Rosaly M. C.   +12 more
openaire   +5 more sources

PARK(ing) time–How park deficiency affects the biological clock in a Drosophila model of Parkinson's disease

open access: yesFEBS Letters, EarlyView.
Drosophila park mutants serve as a model for Parkinson's disease. We used this strain to investigate the connection between oxidative stress and the circadian clock mechanism. We showed that increased oxidative stress affects the physiology of pacemaker cells, disrupting their daily structural plasticity. Lack of rhythmic signaling from pacemaker cells
Kamila Zientara   +3 more
wiley   +1 more source

α‐Synuclein aggregation landscape from phase separation to neurotoxic intermediates

open access: yesFEBS Letters, EarlyView.
Alpha‐synuclein aggregation in Parkinson's disease involves a complex landscape of transient intermediates, including oligomers, fibrils and liquid–liquid phase separation (LLPS). A view is emerging in which LLPS maturation into solid‐like condensates may contribute to the formation of neurotoxic species.
Silvia Arino   +2 more
wiley   +1 more source

Glacial geomorphology of the Ahuriri River valley, central Southern Alps, New Zealand

open access: yesJournal of Maps, 2021
Detailed geomorphological mapping of ice-related and post-glacial landforms is widely used to explain past glacial fluctuations and dynamics. Here we present the first detailed glacial geomorphological description of the landform assemblages produced by ...
Levan G. Tielidze   +3 more
doaj   +1 more source

Modelling stem cell differentiation related processes—A practical overview for biologists

open access: yesFEBS Letters, EarlyView.
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar   +4 more
wiley   +1 more source

Geomorphological mapping of high mountain relief, Federal Republic of Germany (with geomorphology map Königssee, scale 1:25,000)

open access: yes, 1987
Geomorphological mapping of high mountain relief, Federal Republic of Germany : (with geomorphology map Königssee, scale 1:25 000) / Dietrich Barsch ; Klaus Fischer ; Gerhard Stäblein. - In: Mountain research and development. 7. 1987. S.
Stäblein, Gerhard   +2 more
core   +1 more source

Mixed‐class J‐domain protein scaffolds promote expanded aggregate handling and multivalent Hsp70 engagement during functional disaggregase assembly

open access: yesFEBS Letters, EarlyView.
Protein aggregates threaten proteostasis and cell health. In human cells, Hsp70–J‐domain protein‐based disaggregases remove aggregates, but how they assemble remains unclear. Our biochemical findings show that DNAJA2‐ and DNAJB1‐containing disaggregase scaffolds enhance luciferase aggregate targeting, and that Hsp70 recruitment by both J‐domain ...
Anna Szlachcic, Nadinath B. Nillegoda
wiley   +1 more source

Decoding the dynamic extracellular matrix in cancer—3D models and bioscaffolds rewire the rules of tumor progression

open access: yesFEBS Letters, EarlyView.
Cancer progression is regulated by the dynamic matrix code of the tumor microenvironment, which influences cellular behavior and disease development. Importantly, matrix remodeling in three‐dimensional cancer models more accurately reflects in vivo conditions compared to conventional two‐dimensional systems.
Sylvia Mangani   +3 more
wiley   +1 more source

Geomorphological mapping of the Comet 67P/Churyumov-Gerasimenko [PDF]

open access: yes, 2016
OSIRIS, the Scientific Imaging System for Rosetta mission \citep{keller07} has been acquiring images of the nucleus of the comet 67P/Churyumov-Gerasimenko since Aug 2014 with a resolution that allows a detailed analysis of its surface.
Magrin, S.   +17 more
core  

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