George gilbert scott - Open Access .click

Results 31 to 40 of about 3,042,565 (140)

A Test of the Coase Conjecture Using Prices of Electronic Books

Southern Economic Journal, EarlyView.
ABSTRACT The Coase Conjecture predicts that a durable‐goods monopolist without commitment will rapidly cut price toward marginal cost. We test this prediction in the electronic‐book market using release‐day prices. To proxy for marginal cost, we use competitive prices of public‐domain electronic books on the same platforms.
Tim Groseclose, Alex Tabarrok
wiley +1 more source

Five Decades of Dispute: A Triptych. E. J. Corey

The Chemical Record, EarlyView.
In his 2004 Priestley Medal address, E. J. Corey stated, “On May 4, 1964, I suggested to my colleague R. B. Woodward a simple explanation involving the symmetry of the perturbed (HOMO) molecular orbitals for the stereoselective cyclobutene/1,3‐butadiene and 1,3,5‐hexatriene/cyclohexadiene conversions that provided the basis for the further development ...
Jeffrey I. Seeman
wiley +1 more source

Molecular Characterization and Clinical Relevance of Metabolic Expression Subtypes in Human Cancers

Cell Reports, 2018
Summary: Metabolic reprogramming provides critical information for clinical oncology. Using molecular data of 9,125 patient samples from The Cancer Genome Atlas, we identified tumor subtypes in 33 cancer types based on mRNA expression patterns of seven ...
Xinxin Peng +745 more
doaj +1 more source

“Women of the Happy Life”: Prostitution, Public Morality, and Venereal Disease in US‐Occupied Nicaragua, 1912–33

Gender &History, EarlyView.
ABSTRACT During the years of the US occupation (1912–33), Nicaragua's government legally regulated prostitution. Convinced of their objectives to protect society's moral and public health, politicians embarked on a long struggle to apprehend, quarantine, and segregate female prostitutes nationwide.
Eimeel Castillo
wiley +1 more source

From Alaska to Argentina and back: migration routes, migration timing, and wintering areas of adult male Swainson’s Thrushes ( Catharus ustulatus ) from breeding areas in interior Alaska

Avian Conservation and Ecology
The Swainson’s Thrush ( Catharus ustulatus ) is one of the most common migratory passerine birds nesting in the central biogeographic region of Alaska, USA, and exhibits a Nearctic-Neotropical migration.
Carol McIntyre +10 more
doaj +1 more source

Spatial Organization and Molecular Correlation of Tumor-Infiltrating Lymphocytes Using Deep Learning on Pathology Images

Cell Reports, 2018
Summary: Beyond sample curation and basic pathologic characterization, the digitized H&E-stained images of TCGA samples remain underutilized. To highlight this resource, we present mappings of tumor-infiltrating lymphocytes (TILs) based on H&E images ...
Joel Saltz +740 more
doaj +1 more source

Patient‐reported outcomes, postoperative pain and pain relief after day‐case surgery (POPPY): acute pain and recovery during the first 7 days

Anaesthesia, EarlyView.
Summary Introduction The majority of surgical cases in the UK occur in a day‐case setting. Published short‐term follow‐up studies after day‐case surgery are lacking and patterns of recovery including pain and patient reported outcome measures, are largely unknown. Methods Data from the Patient‐reported Outcomes, Postoperative Pain and pain relief after
Matthew Everson +2177 more
wiley +1 more source

Machine Learning Detects Pan-cancer Ras Pathway Activation in The Cancer Genome Atlas

Cell Reports, 2018
Summary: Precision oncology uses genomic evidence to match patients with treatment but often fails to identify all patients who may respond. The transcriptome of these “hidden responders” may reveal responsive molecular states. We describe and evaluate a
Gregory P. Way +737 more
doaj +1 more source

Decoding neuronal vulnerability: Multidimensional analysis of D1R‐ and D2R‐ medium‐sized spiny neurons in Huntington's disease

Brain Pathology, EarlyView.
D1R and D2R MSNs show distinct responses to Huntington's pathology. G&T‐sequencing of pre‐symptomatic MSNs reveals global LINE‐1 downregulation. While D1R‐MSNs display early transcriptomic changes (OXPHOS/translation upregulation) and reduced mutant huntingtin aggregation, D2R‐MSNs exhibit higher nuclear mHTT accumulation and greater CAG somatic ...
Guendalina Bergonzoni +22 more
wiley +1 more source

Pan-Cancer Analysis of lncRNA Regulation Supports Their Targeting of Cancer Genes in Each Tumor Context

Cell Reports, 2018
Summary: Long noncoding RNAs (lncRNAs) are commonly dysregulated in tumors, but only a handful are known to play pathophysiological roles in cancer. We inferred lncRNAs that dysregulate cancer pathways, oncogenes, and tumor suppressors (cancer genes) by ...
Hua-Sheng Chiu +736 more
doaj +1 more source

biology general
francis skidmore
hereford screen

hereford cathedral
hadron-hadron scattering experiments
covid-19

sars-cov-2
rood screen