Results 31 to 40 of about 145,901 (277)

Engineering Concentration‐Dependent Intravitreal Mobility via Cyclic Arginine‐Enriched Nanocarrier Surface Modification: In Vivo Proof‐of‐Concept in a Porcine Large Animal Model

open access: yesAdvanced Healthcare Materials, EarlyView.
In this study, Hammer et al. highlight cyclic‐arginine surface engineering as a highly biocompatible, controllable, and concentration‐dependent regulator of intravitreal nanoparticle mobility in vivo in a translational large animal model. The cyclic arginine surface‐modification supports the development of next‐generation biomaterials for long‐acting ...
Maximilian Hammer   +12 more
wiley   +1 more source

Brief von Gerd-Klaus Kaltenbrunner an Kurt Rothschild

open access: yes
BRIEF VON GERD-KLAUS KALTENBRUNNER AN KURT ROTHSCHILD Brief von Gerd-Klaus Kaltenbrunner an Kurt Rothschild ([1]
Kaltenbrunner, Gerd-Klaus
core   +3 more sources

GERD: A practical approach [PDF]

open access: yesCleveland Clinic Journal of Medicine, 2020
Gastroesophageal reflux disease (GERD) is mainly a clinical diagnosis based on typical symptoms of heartburn and acid regurgitation. Current guidelines indicate that patients with typical symptoms should first try a proton pump inhibitor (PPI). If reflux symptoms persist after 8 weeks on a PPI, endoscopy of the esophagus is recommended, with biopsies ...
Andrew, Young   +2 more
openaire   +2 more sources

Automating AI Discovery for Biomedicine Through Knowledge Graphs and Large Language Models Agents

open access: yesAdvanced Intelligent Discovery, EarlyView.
This work proposes a novel framework that automates biomedical discovery by integrating knowledge graphs with multiagent large language models. A biologically aligned graph exploration strategy identifies hidden pathways between biomedical entities, and specialized agents use this pathway to iteratively design AI predictors and wet‐lab validation ...
Naafey Aamer   +3 more
wiley   +1 more source

Prevalence of GERD Symptoms and its Related Risk Factors Among Medical Students in Saudi Arabia

open access: yesJournal of Pharmacy and Bioallied Sciences
Objective: This study was carried out to assess the prevalence of gastroesophageal reflux disease (GERD) symptoms and identify risk factors among medical students in Saudi Arabia.
Abdulwahed A. Alotay   +12 more
doaj   +1 more source

Dexansoprazole MV in the treatment of gastroesophageal reflux disease

open access: yesМедицинский совет, 2019
Dexlensoprazole MB is the R-enantiomer of lansoprazole and is currently the only proton pump inhibitor with the new Dual Delayed Release delivery technology. The pharmacokinetics of the drug shows two peaks of release in the 12-finger and small intestine;
М. V. Leonova, E. Е. Alimova
doaj   +1 more source

Assessment of Growth in Cardio‐Facio‐Cutaneous Syndrome

open access: yesAmerican Journal of Medical Genetics Part A, EarlyView.
ABSTRACT Cardio‐facio‐cutaneous (CFC) syndrome is a rare, multiple congenital anomaly disorder in which individuals commonly experience faltering growth; however, systematic analysis of growth parameters in this disorder has not been performed. We recruited 69 participants with CFC through CFC International and collected data on assessing height ...
Kari Johnston   +6 more
wiley   +1 more source

Omeprazol in the therapy of acid-base disorders

open access: yesМедицинский совет, 2015
Proton pump inhibitors are the most effective treatment for all types of acid-base disorders. Despite differences between them, the available evidence demonstrated nearly the same clinical efficacy of various representatives of this group of drugs.
O. N. Minushkin, L. V. Maslovskiy
doaj   +1 more source

The Pharmacological Management of Gerd

open access: yes, 2020
This thesis explores the current pharmacological therapy of Gerd, which includes Antacids, PPI's, H2RA's, the efficacy in the clinical management of Gerd. Potential adverse effects, including drug interactions and pharmacodynamics.
Emukah-Brown, Praise Uche
core  

Heterozygous Variants in LRP1 Cause a Neurodevelopmental Disorder With Congenital Heart Defects

open access: yesAmerican Journal of Medical Genetics Part A, EarlyView.
ABSTRACT LRP1 encodes the low‐density lipoprotein (LDL) receptor‐related protein 1 (LRP1), a transmembrane protein involved in endocytosis and activation of multiple signaling pathways. LRP1 variants have been implicated in the pathogenesis of congenital heart defects (CHD), Alzheimer's disease, and neurodevelopmental disorders (NDD).
Alyssa L. Rippert   +31 more
wiley   +1 more source

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