Results 111 to 120 of about 5,134,159 (382)

Evaluation of geriatric assessment and management on the toxic effects of cancer treatment (GAP70+): a cluster-randomised study

The Lancet, 2021
S. Mohile, M. Mohamed, Huiwen Xu, E. Culakova, K. Loh, A. Magnuson, M. Flannery, Spencer Obrecht, N. Gilmore, E. Ramsdale, R. Dunne, T. Wildes, S. Plumb, A. Patil, M. Wells, L. Lowenstein, M. Janelsins, K. Mustian, J. Hopkins, J. Berenberg, Navin Anthony, W. Dale   +21 more
semanticscholar   +1 more source

Targeting the ARRDC3–DRP1 Axis via hUMSC‐Derived Exosomal CRYAB for Neuroprotection in Cerebral Ischemia/Reperfusion Injury

Advanced Healthcare Materials, EarlyView.
Intranasally administered hUMSC‐derived exosomes modulate the CRYAB–ARRDC3–Drp1 axis, alleviating mitochondrial dysfunction and ferroptosis, enhancing neuronal survival, reducing oxidative stress, and promoting functional recovery in ischemia‐reperfusion injury, offering a promising therapeutic strategy for ischemic stroke.
Rong ji, Zengyu Zhang, Zhuohang Liu, Kaicheng Yang, Xueyu Mao, Min Chu, Yong Wang, Jing Zhao   +7 more
wiley   +1 more source

Examining evidence based resistance plus balance training in community-dwelling older adults with complex health care needs: Trial protocol for the Muscling Up Against Disability project [PDF]

, 2017
Available online 6 October 2016Abstract not availableJustin W.L.
Gardiner, Paul, Henwood, Tim, Hodgkinson, Brent, Keogh, Justin W L, Rouse, Kevin, Tuckett, Anthony   +5 more
core   +2 more sources

Serotonergic System‐Targeted Nucleic Acid Hydrogel Coordinates Excitability Restoration and Circuit Reconstruction for Spinal Cord Injury Therapy

Advanced Materials, EarlyView.
The study reports a DNA/RNA heteroduplex hydrogel (SeroPTEN‐CG) that undergoes DNase‐mediated hydrogel‐to‐nanogel transition for spinal cord injury therapy by targeting the serotonergic system, combining 5‐hydroxytryptamine (5‐HT)‐mediated excitability restoration to reactivate dormant interneurons with phosphatase and tensin homolog (PTEN)‐targeted ...
Chunlin Li, Xiaoqing Zhao, Kai Jiang, Haixia Kang, Shuo Liu, Linlin Jiang, Baoshuai Bai, Haonan Cui, Ziyang Zhang, Menglei Dong, Ruizhi Zhang, Chenbo Zou, Shenghui Shang, Chi Zhang, Xiangchuang Fan, Lijuan Zhu, Huiquan Duan, Chuan Zhang, Shiqing Feng, Hengxing Zhou   +19 more
wiley   +1 more source

Autonomous Comprehensive Geriatric Assessment [PDF]

, 2017
This paper presents the MARIO’s CGA (Comprehensive Geriatric Assessment) module for the Kompai platform that aims at autonomously performing and managing the execution of specific tests required in the CGA process. The application relies on the CGA ontology, which is part of the Mario Ontology Network (MON)4, as a support to the execution of the ...
Asprino Luigi, Gangemi Aldo, Nuzzolese Andrea Giovanni, Presutti Valentina, Recupero Diego Reforgiato, Russo Alessandro   +5 more
openaire   +3 more sources

THEORETICAL FRAMEWORK FOR AN ARTIFICIAL INTELLIGENCE–BASED COMPREHENSIVE GERIATRIC ASSESSMENT [PDF]

, 2023
Adam G. Golden
openalex   +1 more source

Comprehensive Geriatric Assessment as a Versatile Tool to Enhance the Care of the Older Person Diagnosed with Cancer

Geriatrics, 2019
The comprehensive geriatric assessment (CGA) is a versatile tool for the care of the older person diagnosed with cancer. The purpose of this article is to detail how a CGA can be tailored to Ambulatory Geriatric Oncology Programs (AGOPs) in academic ...
J. Overcash, Nikki Ford, Elizabeth Kress, Caitlin Ubbing, N. Williams   +4 more
semanticscholar   +1 more source

Genome‐Wide by Lifetime Environment Interaction Studies of Brain Imaging Phenotypes

Advanced Science, EarlyView.
This study explores genome‐wide by lifetime environment interactions on brain imaging phenotypes. Gene‐environment interactions explain more phenotypic variance than main effects, pinpoint regulatory variants, and reveal exposure‐specific biological pathways.
Sijia Wang, Meiyun Wang, Peng Zhang, Jingliang Cheng, Longjiang Zhang, Wenzhen Zhu, Shijun Qiu, Zuojun Geng, Guangbin Cui, Yongqiang Yu, Weihua Liao, Xi‐Nian Zuo, Hui Zhang, Bo Gao, Xiaojun Xu, Tong Han, Zhenwei Yao, Quan Zhang, Feng Liu, Qiang Xu, Jiayuan Xu, Jilian Fu, Nana Liu, Yuan Ji, Jie Tang, Lining Guo, Mengge Liu, Xiaoxiao Xiao, Xiaoxuan Liu, Wei Li, Caihong Wang, Wei Wei, Dapeng Shi, Su Lui, Zhihan Yan, Feng Chen, Jing Zhang, Wen Shen, Yanwei Miao, Dawei Wang, Jia‐Hong Gao, Yunjun Yang, Kai Xu, Junfang Xian, Bing Zhang, Xiaochu Zhang, Zhaoxiang Ye, Le Yu, Wen Qin, Meng Liang, Chunshui Yu, the CHIMGEN Consortium   +51 more
wiley   +1 more source

Prevalence and risk factors of sarcopenia among adults living in nursing homes [PDF]

, 2015
Objectives: Sarcopenia is a progressive loss of skeletal muscle and muscle function, with significant healthand disability consequences for older adults.
Beller, Elaine M., Henwood, Tim R., Keogh, Justin W L, Mitchell, Geoffrey K., Senior, Hugh E.   +4 more
core   +1 more source

Costs of medication in older patients: before and after comprehensive geriatric assessment

Clinical Interventions in Aging, 2018
Background Polypharmacy and inappropriate drug use cause numerous complications, such as cognitive impairment, frailty, falls, and functional dependence.
G. Unutmaz, P. Soysal, Busra Tuven, A. Işık   +3 more
semanticscholar   +1 more source