Biocatalytic Nanoregulators Restore Joint Redox‐Immune Homeostasis in Rheumatoid Arthritis
Advanced Science, EarlyView.Mesenchymal stem cell‐derived extracellular vesicles (EVs) coat ruthenium‐loaded metal‐organic frameworks (Ru@ZrMOF), creating a targeted therapeutic (Ru@ZrMOF/EVs). This platform scavenges ROS, generates oxygen, and polarizes macrophages from M1 to M2, alleviating inflammation, inhibiting pannus, promoting cartilage repair, and downregulating HIF‐1α ...
Xingheng Wang +7 more
wiley +1 more source
A systematic review of the relationship between behavioral and psychological symptoms (BPSD) and caregiver well-being [PDF]
, 2016 Background: Behavioural and psychological symptoms in dementia (BPSD) are important predictors of institutionalisation as well as caregiver burden and depression. Previous reviews have tended to group BPSD as one category with little focus on the role of
Charlesworth, Georgina +4 more
core +4 more sources
Metformin Impairs Breast Cancer Growth through the Inhibition of PRMT6
Advanced Science, EarlyView.Metformin has a biological activity against breast cancer. However, it is largely unknown about its precise therapeutic targets. Here, histone arginine methyltransferase PRMT6 is identified as a new anti‐cancer target for metformin. Metformin directly binds PRMT6 and inhibits its ability to catalyze histone H3R2 asymmetric dimethylation (H3R2me2a ...
Yinsheng Wu +9 more
wiley +1 more source
There’s no apprenticeship for Alzheimer’s: The caring relationship when an older person experiencing dementia falls [PDF]
, 2011 © Cambridge University Press 2011Older people experiencing dementia are twice as likely to fall with consequences of serious injury, reduction in everyday activity, admission to long-term care and mortality.
McIntyre, AE, Reynolds, F
core +1 more source
Archives of Gerontology and Geriatrics PlusBackground: The elderly population often has complex health needs due to multimorbidity, polypharmacy, and inappropriate prescriptions. Clinical pharmacists play an important role in optimizing pharmacotherapy as a part of a multidisciplinary geriatric ...
Jehath Syed +7 more
doaj +1 more source
Defining the Domain of Geriatric Medicine in an Urban Public Health System Affiliated with an Academic Medical Center [PDF]
, 2008 The American Geriatrics Society has recommended a reexamination of the roles and deployment of providers with expertise in geriatric medicine. Healthcare systems use a variety of strategies to maximize their geriatric expertise.
Besdine +14 more
core +1 more source
Geriatric mental health: The challenges for India
Journal of Geriatric Mental Health, 2018 Geriatric mental health has yet to receive its due recognition in India. Geriatric mental health is plagued by many challenges that prevent the development and progress of its services.
Pragya Lodha, Avinash De Sousa
doaj +1 more source
Functional changes during hospital stay in older patients admitted to an acute care ward : a multicenter observational study [PDF]
, 2014 Objectives: Changes in physical performance during hospital stay have rarely been evaluated. In this study, we examined functional changes during hospital stay by assessing both physical performance and activities of daily living.
Corsonello, Andrea +6 more
core +2 more sources
An uncommon orthogeriatric syndrome: a case of Ogilvie’s syndrome
Geriatric CareAcute colonic pseudo-obstruction (ACPO), also known as Ogilvie’s syndrome, is an uncommon postoperative complication of major orthopedic surgery that is characterized by massive colonic dilatation and the potential for substantial morbidity and ...
Elisa Salsano +9 more
doaj +1 more source
Geriatric patients\u27 expectations of their physicians: findings from a tertiary care hospital in Pakistan [PDF]
, 2009 Background: Geriatric health is a neglected and under-explored area internationally and in Pakistan. We aimed to ascertain the expectations of the geriatric Patients from their physicians and the factors associated with Patient satisfaction in this ...
Khalid, Umair +2 more
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