Results 141 to 150 of about 298,884 (351)

National Blueprint: Increasing Physical Activity Among Adults Age 50 and Older [PDF]

open access: yes, 2001
Outlines a variety of approaches for organizations, associations, and agencies to plan strategies to help people age 50 and older increase their physical ...

core  

Carbon Monoxide Nanomodulator Reverses Ischemia‐Reperfusion Injury in Stroke: A Novel Dual‐Channel Therapy Mode of Co‐driving Neuroprotection and Neurogenesis

open access: yesAdvanced Science, EarlyView.
This work develops a biomimetic and reactive oxygen species‐activated carbon monoxide (CO) nanogenerator to penetrate blood‐brain barrier, arrive in stroke‐affected regions, and release CO in a controlled manner for an innovative dual‐channel therapy strategy via co‐driving neuroprotection and neurogenesis.
Xuegang Niu   +17 more
wiley   +1 more source

Profile of 10,935 elderly patients attending the geriatrics department of a medical college: A retrospective study from South India

open access: gold, 2023
Sandhya K. Neelamana   +4 more
openalex   +1 more source

Nortriptyline Inhibits Lysosomal Exocytosis‐Mediated SASP During Gastric Cancer Progression via Targeting HOXA1‐PITX2 Phase Separation

open access: yesAdvanced Science, EarlyView.
This study identifies that HOXA1 facilitates transcriptional activity of PITX2 in liquid condensates, resulting in up‐regulation of MCOLN1 and RAB3A followed by lysosomal exocytosis of LGALS1 and IGFBP7 from senescent cells, thus activating AKT signaling and EMT.
Yi Zhou   +10 more
wiley   +1 more source

Research Databases and Geriatrics and Gerontology Journals: The Comparison of Databases and Their Covered Journals

open access: yesSālmand, 2016
Objectives: The database and the journals indexed under them are the most important information resources for students and experts in various disciplines, including geriatrics.
Mansoureh Feizabadi   +2 more
doaj  

BRIGHT Enables High‐SNR Live‐Cell Imaging of Non‐Repetitive Sequences via Bivalent Fluorescent Nanobody‐Mediated Cascade‐Dependent Illumination

open access: yesAdvanced Science, EarlyView.
BRIGHT is a newly developed live‐cell imaging system that integrates cascade amplification with background denoising through the bivalent binding capability and antigen‐dependent stability of a bivalent fluorescent nanobody targeting ALFA peptides.
Lei Feng   +9 more
wiley   +1 more source

Cancer Stem Cells Shift Metabolite Acetyl‐Coenzyme A to Abrogate the Differentiation of CD103+ T Cells

open access: yesAdvanced Science, EarlyView.
Lei et al. demonstrate that cancer stem cells (CSCs) play a pivotal role in impairing the differentiation of CD103+ T cells in patients with non‐small‐cell lung cancer. The key mechanism involves CSC‐derived acetyl‐CoA, which disrupts CD103+ T cell differentiation by sequentially inducing acetylation and ubiquitination of the Blimp‐1 protein. Targeting
Jiaxin Lei   +10 more
wiley   +1 more source

Analysis of foodborne disease surveillance of geriatrics from 2018 to 2022 in China’s Mainland

open access: yesZhongguo shipin weisheng zazhi
ObjectiveTo provide scientific basis for the prevention and control of foodborne diseases among the geriatrics in China’s Mainland, the epidemiological characteristics of foodborne diseases was understood.MethodsInformation on acute gastroenteritis cases
FAN Penghui   +13 more
doaj   +1 more source

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