Results 141 to 150 of about 285,790 (386)
Orthogeriatrics in Malta : a 3 year experience [PDF]
, 2016 The orthogeriatric service in Malta started in 2012 and expanded in 2014. From admission, the patient is offered a ward based hip fracture programme that includes orthogeriatric assessment, management and co-ordinated multidisciplinary review.
Bugeja, Vincent +8 more
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Advanced Science, EarlyView.This study develops a cartilage‐targeted DNA origami system (OCS) that protects and delivers si‐Stat3 to chondrocytes. OCS reduces MMP13 expression, enhances extracellular matrix stability, and lowers oxidative stress while improving cell survival. In vivo, OCS decreases cartilage degradation biomarkers and promotes tissue repair factors, demonstrating
Qi Lv +8 more
wiley +1 more source
Education and training in geriatrics: guiding the generational change of health professionals
Geriatric CareThe increased volume of the aged population, the complexity of patients, and the updates in the legislative aspects linked to older people constitute various challenges for geriatrics.
Liliana Mazza, Lorenzo Palleschi
doaj +1 more source
Palliative Care Academic Career Awards: A Public-Private Partnership to Improve Care for the Most Vulnerable [PDF]
, 2003 Palliative care, an increasingly important medical field that focuses on the relief of pain and suffering, is in danger of not being able to meet the needs of America's aging population, or anyone of any age suffering from serious or life-threatening ...
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Aberrant Mitochondrial Metabolism in Alzheimer's Disease Links Energy Stress with Ferroptosis
Advanced Science, EarlyView.Alves et al. reveal how energy loss and oxidative stress, two major features of Alzheimer's disease, are connected. Mitochondria controls the flux of the antioxidant glutathione (GSH), via facilitating both its production and consumption. Energy restriction limits GSH synthesis, conferring vulnerability to cell death by ferroptosis, implicated as a ...
Francesca Alves +17 more
wiley +1 more source
Competency Framework Of Palliative Medicine For Geriatricians [PDF]
Geriatrics, Gerontology and AgingINTRODUCTION AND OBJECTIVE: Despite a great interface between palliative care (PC) and geriatrics, there are currently no curriculum proposals of palliative medicine (PM) competencies for geriatricians in Brazil. Thus, the aim was to develop a competency
Laiane Moraes Dias +8 more
doaj +1 more source
Advanced Science, EarlyView.Fusobacterium nucleatum (Fn) enrichment has been identified in colorectal cancer and its liver metastases. This study develops neutrophil‐mimicking nanoparticles with multiple targeting capabilities encapsulating metronidazole and oxaliplatin for antibacterial and anticancer purposes. This approach reverses the epithelial mesenchymal transition process
Yanan Niu +7 more
wiley +1 more source
The Immune Microenvironment: New Therapeutic Implications in Organ Fibrosis
Advanced Science, EarlyView.This review summarizes recent advances in understanding the immune microenvironment's role in fibrosis, focusing on phenotypic/functional alterations of immune cells and their dynamic interactions with other cellular constituents within tissues. The authors further explore therapeutic opportunities and challenges in targeting immune microenvironment ...
Xiangqi Chen +6 more
wiley +1 more source
Importance of Geriatrics [PDF]
Journal of the American Medical Association, 1914 To the Editor: —Canstatt (Krankheiten des hoheren Alters und ihre Heilung, Erlangen, 1839) says: "Medical literature, especially of the present day, abounds in works on diseases of women and children. The pathology of certain organs and of certain classes of diseases receives exceptional attention. Bare and neglected in comparison with these lovingly
openaire +3 more sources