Results 231 to 240 of about 238,883 (265)
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Germ cell lineage differentiation in non‐seminomatous germ cell tumours

The Journal of Pathology, 2005
AbstractHuman germ cell tumours (GCTs) have long fascinated investigators for a number of reasons. Being pluripotential tumours, they can differentiate into both extra‐embryonic and embryonic (somatic) tissues. However, it has never been shown convincingly that, in humans, these tumours are truly totipotent and can also give rise to the germ lineage ...
Honecker, F   +7 more
openaire   +2 more sources

GERM CELL TUMORS OF THE OVARY

International Journal of Gynecological Pathology, 1982
During the review period, a number of papers were published reporting series of patients with malignant ovarian germ cell tumors and describing the increasingly successful worldwide trend observed in treatment of such patients. Publications dealing solely with the successful management of patients with pure dysgerminoma, using surgery followed by ...
openaire   +2 more sources

[Embryonal germ cells and germ cell tumors].

Verhandlungen der Deutschen Gesellschaft fur Pathologie, 2008
Testicular germ cell tumors comprise of group of pluripotent tumors including seminomas and nonseminomas, arise from intratubular germ cell neoplasia and originate from the primordial germ cells/ gonocytes. Many well characterized markers of embryonic stem cells including CD9, PODXL and centromere-specific histone-H3-like protein CENPA are consistently
K, Biermann   +14 more
openaire   +1 more source

Germ cell cancer of the testis

Current Opinion in Oncology, 1995
New insights into the etiology and specifically the role of atrophy in generating increased gonadotropin drive have come from a case-control study of 794 patients. This study demonstrated possible evidence for trauma and infection-related atrophy, although of most interest from the point of view of the gonadotropin drive hypothesis is the observation ...
openaire   +3 more sources

Primordial Germ Cells and Germ Line Stem Cells

2015
Germ cells are a sexual reproductive cell type at any stage from primordial germ cells (PGCs) to mature gametes. Germ line stem cells are important for genetic transmission to future generations. In this review, we focus on female germ line stem cells (FGSCs), spermatogonial stem cells (SSCs), and PGCs.
Ji Wu   +5 more
openaire   +1 more source

Germ Plasm and the Differentiation of the Germ Cell Line

1976
Publisher Summary This chapter discusses germ plasm and the differentiation of the germ cell line. Germ plasm is defined as a substance present in the cytoplasm of gametes, which is segregated into specific cells during blastulation and determines that those cells shall become the progenitors of the germ cell line during subsequent development.
openaire   +2 more sources

In vitro reconstitution of the whole male germ-cell development from mouse pluripotent stem cells

Cell Stem Cell, 2021
Chika Yamashiro   +2 more
exaly  

Human germ cell tumours from a developmental perspective

Nature Reviews Cancer, 2019
Wolter Oosterhuis   +2 more
exaly  

Specifying and protecting germ cell fate

Nature Reviews Molecular Cell Biology, 2015
Susan Strome   +2 more
exaly  

Genomic evolution and chemoresistance in germ-cell tumours

Nature, 2016
, Colin Turnbull, Eliezer Van Allen
exaly  

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