Results 281 to 290 of about 462,838 (340)

TRAPPC2l Participates in Male Germ Cell Development by Regulating Cell Division. [PDF]

Cell Prolif
Wang M, Li J, Liu B, Shen Z, Chen M, Cui X, Liu H, Gao F, Zhao H.   +8 more
europepmc   +1 more source

Mucosal‐associated invariant T cells in rheumatic diseases.

Arthritis &Rheumatology, Accepted Article.
Mucosal‐associated invariant T (MAIT) cells are innate‐like T cells defined by their semi‐invariant T cell receptor (TCR) and restriction by the MHC class I‐related molecule (MR1). These cells are primarily activated by microbial‐derived metabolites presented by MR1 or by cytokines. Upon activation, MAIT cells rapidly produce pro‐inflammatory cytokines,
Manon Lesturgie‐Talarek, Virginie Gonzalez, Lucie Beaudoin, Noémie Sénot, Corinne Miceli‐Richard, Yannick Allanore, Agnès Lehuen, Jerôme Avouac   +7 more
wiley   +1 more source

Expert Perspective: Diagnosis and Treatment of Castleman Disease

Arthritis &Rheumatology, Accepted Article.
Summary Castleman disease (CD) is a major diagnostic challenge for Rheumatologists. Unicentric CD (UCD) involves one enlarged lymph node region whereas multicentric CD (MCD) involves multiple enlarged lymph node regions. Both UCD and MCD may exhibit a wide range of symptoms that overlap with other immune‐mediated conditions.
Luke Y.C. Chen, Lu Zhang, David C. Fajgenbaum   +2 more
wiley   +1 more source

Topoisomerase 3b facilitates piRNA biogenesis to promote transposon silencing and germ cell development. [PDF]

Cell Rep
Lee SK, Shen W, Wen W, Joo Y, Xue Y, Park A, Qiang A, Su S, Zhang T, Zhang M, Fan J, Zhang Y, De S, Gainetdinov I, Sharov A, Maragkakis M, Wang W.   +16 more
europepmc   +1 more source

Supporting doctors' professional identity development through specialist training

Anatomical Sciences Education, EarlyView.
Abstract Anatomy‐centric specialties such as surgery, radiology, and anatomical pathology (AP) have workforce shortages, with attrition during the training phase proposed as a contributing factor. Current understanding of the reasons behind trainee attrition is limited, and there have been calls to increase the depth and richness of research in this ...
Shemona Y. Rozario, Melanie K. Farlie, Mahbub Sarkar, Michelle D. Lazarus   +3 more
wiley   +1 more source

Age, Race, and Ethnicity of Maternal Grandparents in Autism Spectrum Disorder, a California Multigenerational Study

Autism Research, EarlyView.
ABSTRACT We investigated associations between maternal grandparents' age and autism spectrum disorders (ASD) in grandchildren, exploring differences by race/ethnicity. In a multigenerational California birth cohort study including 1,743,998 and 1,630,722 mother–child pairs (with 27,975 and 25,816 ASD cases, respectively), we examined ASD risk by ...
Ting Chow, Qi Meng, Jingyuan Xiao, Karl O'Sharkey, Zeyan Liew, Beate Ritz   +5 more
wiley   +1 more source

Yolk Sac Elements in Tumors Derived from Pluripotent Stem Cells: Borrowing Knowledge from Human Germ Cell Tumors. [PDF]

Int J Mol Sci
van Soest M, Montilla-Rojo J, Eleveld TF, Looijenga LHJ, Salvatori DCF.   +4 more
europepmc   +1 more source

Design and Synthesis of Triazole‐Based p‐tert‐Butylcalix[4]Arene Conjugates and Evaluation of Their Antimicrobial, Antibiofilm, and Anti‐Quorum‐Sensing Activities

Biotechnology and Applied Biochemistry, EarlyView.
ABSTRACT Macrocyclic calix[n]arenes have many applications, with diverse structures that can easily be functionalized either on upper or lower rims, mostly to impart solubility and improve biological activities. In this study, triazole‐based p‐tert‐butylcalix[4]arene conjugates (AT10a and AT10b) and their p‐tert‐butylphenol analogs (AT10b and AT11b ...
Alfred Ngenge Tamfu, Selahattin Bozkurt, Ozgur Ceylan   +2 more
wiley   +1 more source

Mouse SPAG6L, a Key Cytoskeleton Modulator Essential for Male Germ Cell Development, Is Not Required for Sertoli Cell Function. [PDF]

Cells
Li T, Li W, Zheng C, Dufour JM, Walker WH, Yuan S, Zhang Z.   +6 more
europepmc   +1 more source

The Stem Cell Transcription Factor OCT4 Silences Target DNA Methyltransferase 1 to Strengthen DNA Damage Response in Cisplatin‐Treated Gastric Cancer Cells

Biotechnology and Applied Biochemistry, EarlyView.
ABSTRACT OCT4 plays a crucial role in the DNA damage response(DDR) mechanism, whereas cisplatin (CDDP) acts as an anti‐tumor agent by inducing DDR. This study aimed to investigate the role of OCT4 in regulating DNA methyltransferase 1 (DNMT1) in CDDP‐treated gastric cancer (GC).
Zhengzheng Yan, Xiaoqian Bu, Haixia Chen, Chongren Ren, Ji Li, Yongjie Wu, Jun Xing   +6 more
wiley   +1 more source