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How germ granules promote germ cell fate
Nature Reviews GeneticsGerm cells are the only cells in the body capable of giving rise to a new organism, and this totipotency hinges on their ability to assemble membraneless germ granules. These specialized RNA and protein complexes are hallmarks of germ cells throughout their life cycle: as embryonic germ granules in late oocytes and zygotes, Balbiani bodies in immature ...
Melissa C. Pamula, Ruth Lehmann
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[Embryonal germ cells and germ cell tumors].
Verhandlungen der Deutschen Gesellschaft fur Pathologie, 2008Testicular germ cell tumors comprise of group of pluripotent tumors including seminomas and nonseminomas, arise from intratubular germ cell neoplasia and originate from the primordial germ cells/ gonocytes. Many well characterized markers of embryonic stem cells including CD9, PODXL and centromere-specific histone-H3-like protein CENPA are consistently
K, Biermann +14 more
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Human germ cell tumours from a developmental perspective
Nature Reviews. Cancer, 2019J. Oosterhuis, Leendert H. J. Looijenga
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Male Germ Cell Transplantation
Reproduction in Domestic Animals, 2008ContentsTransplantation of male germ line stem cells from a donor animal to the testes of an infertile recipient was first described in 1994. Donor germ cells colonize the recipient’s testis and produce donor‐derived sperm, such that the recipient male can distribute the genetic material of the germ cell donor.
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Seminars in Surgical Oncology, 1999
Pediatric germ cell tumors represent a diverse group of tumors that present from in utero through adolescence at many nongonadal locations, from the neck to the sacrococcygeal region. Surgical resection remains the central element of management, and accurate surgical staging is essential to properly ascertain the correct risk-based treatment.
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Pediatric germ cell tumors represent a diverse group of tumors that present from in utero through adolescence at many nongonadal locations, from the neck to the sacrococcygeal region. Surgical resection remains the central element of management, and accurate surgical staging is essential to properly ascertain the correct risk-based treatment.
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