Results 321 to 330 of about 462,838 (340)
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THE RADIOSENSITIVITY OF GERM CELLS

Biological Reviews, 1964
SummaryThe radiosensitivity of germ cells depends on (a) the criterion by which it is assessed, and (b) the developmental stage at the time of irradiation. For any given parameter and cell‐type, the final effect exerted by ionizing radiations depends on the genetic make‐up and age of the organism; type of irradiation; method of irradiation (acute ...
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Germ cell transplantation

Molecular and Cellular Endocrinology, 2002
Transplantation of germ cells leads to restoration of spermatogenesis from spermatogonial stem cells. The original description of germ cell transplantation in 1994 has led to new approaches to explore many basic aspects of spermatogonial physiology.
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Ovarian Germ Cells

2006
Surface cells in adult ovaries represent germ line-competent embryonic stem cells. They are a novel type of totipotent progenitors for distinct cell types including female germ cells/oocytes, with the potential for use in the autologous treatment of ovarian infertility and stem cell therapy.
Antonin Bukovsky   +3 more
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GERM CELL TUMORS OF THE OVARY

International Journal of Gynecological Pathology, 1982
During the review period, a number of papers were published reporting series of patients with malignant ovarian germ cell tumors and describing the increasingly successful worldwide trend observed in treatment of such patients. Publications dealing solely with the successful management of patients with pure dysgerminoma, using surgery followed by ...
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Immature germ cell conception—in vitro germ cell manipulation

Best Practice & Research Clinical Endocrinology & Metabolism, 2000
Experimental studies in laboratory animals have shown that successful conception can be achieved by fertilizing oocytes with immature male germ cells. This gave rise to the concept that immature germ cells recovered from the testes of azoospermic men with maturation arrest may be used for assisted reproduction.
Ermanno Greco   +2 more
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Pediatric germ cell tumors [PDF]

open access: possibleSeminars in Surgical Oncology, 1999
Pediatric germ cell tumors represent a diverse group of tumors that present from in utero through adolescence at many nongonadal locations, from the neck to the sacrococcygeal region. Surgical resection remains the central element of management, and accurate surgical staging is essential to properly ascertain the correct risk-based treatment.
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Germ cell lineage differentiation in non‐seminomatous germ cell tumours

The Journal of Pathology, 2005
AbstractHuman germ cell tumours (GCTs) have long fascinated investigators for a number of reasons. Being pluripotential tumours, they can differentiate into both extra‐embryonic and embryonic (somatic) tissues. However, it has never been shown convincingly that, in humans, these tumours are truly totipotent and can also give rise to the germ lineage ...
Diego H. Castrillon   +7 more
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Primordial Germ Cells and Germ Line Stem Cells

2015
Germ cells are a sexual reproductive cell type at any stage from primordial germ cells (PGCs) to mature gametes. Germ line stem cells are important for genetic transmission to future generations. In this review, we focus on female germ line stem cells (FGSCs), spermatogonial stem cells (SSCs), and PGCs.
Xingxing Mei   +5 more
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Germ cell cancer of the testis

Current Opinion in Oncology, 1995
New insights into the etiology and specifically the role of atrophy in generating increased gonadotropin drive have come from a case-control study of 794 patients. This study demonstrated possible evidence for trauma and infection-related atrophy, although of most interest from the point of view of the gonadotropin drive hypothesis is the observation ...
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Are cranial germ cell tumours really tumours of germ cells?

Neuropathology and Applied Neurobiology, 2006
Germ cell tumours of the brain and those that occur in the gonads are believed to share a common origin from germ cell progenitors. This ‘germ cell theory’ rests upon similar histopathology between these tumours in different locations and the belief that endogenous somatic cells of the brain could not give rise to the range of cell types seen in germ ...
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