Results 81 to 90 of about 448,990 (214)

Management of germ cell tumors in children: Approaches to cure [PDF]

, 2002
The introduction of cisplatinum chemotherapy and current advances in the surgical treatment have resulted in a dramatic improvement of the prognosis of children with malignant germ cell tumors (GCT).
Calaminus, G., Göbel, U., Haas, R. J., Schmidt, P., Schneider, D. T.   +4 more
core   +1 more source

Germ Cells Are Forever [PDF]

Cell, 2008
Germ cells are the only cell type capable of generating an entirely new organism. In order to execute germline-specific functions and to retain the capacity for totipotency, germ cells repress somatic differentiation, interact with a specialized microenvironment, and use germline-specific networks of RNA regulation.
Cinalli, Ryan M., Rangan, Prashanth, Lehmann, Ruth   +2 more
openaire   +2 more sources

A nucleic acid binding protein map of germline regulation in Caenorhabditis elegans

Nature Communications
Fertility requires the faithful proliferation of germ cells and their differentiation into gametes. Controlling these cellular states demands precise timing and expression of gene networks. Nucleic acid binding proteins (NBPs) play critical roles in gene
Wei Cao, Qi Fan, Gemmarie Amparado, Dean Begic, Rasoul Godini, Sandeep Gopal, Roger Pocock   +6 more
doaj   +1 more source

Cisplatin-based chemotherapy of testicular cancer - Two decades after a major breakthrough [PDF]

, 2000
Two decades ago the introduction of cisplatin-based combination chemotherapy has dramatically improved the prognosis of patients with metastatic testicular cancer, At present 3 cycles of cisplatin, etoposide and bleomycin are considered as standard ...
Gerl, Arthur
core   +1 more source

The topological structure of 2D disordered cellular systems

, 1997
We analyze the structure of two dimensional disordered cellular systems generated by extensive computer simulations. These cellular structures are studied as topological trees rooted on a central cell or as closed shells arranged concentrically around a ...
Aste, T., Dubertret, B., Ohlenbusch, H. M., Rivier, N.   +3 more
core   +3 more sources

Primordial follicular assembly in humans : revisited [PDF]

, 2009
Peer ...
A. Maheshwari, Baker, Donovan, Gumienny, Konishi, P. A. Fowler, Pinkerton, Satoh, Vaskivuo   +8 more
core   +1 more source

Induction of germ cell-like cells from deleted in azoospermia-like enhanced green fluorescent protein gene knock-in chicken somatic cells via transgenic expression of pluripotency and germ cell-specific transcription factors [PDF]

Animal Bioscience
Objective Germ cell identity is regulated by the coordinated action of multiple key transcription factors during embryonic development, which includes the induction and control of germ-line-specific gene expression. The expression of DEAD-box helicase 4 (
Bo Ram Lee, Hyeon Yang, Sun Keun Jung, Sung June Byun, Tae Sub Park   +4 more
doaj   +1 more source

Germ cell dynamics during nest breakdown and formation of the primordial follicle pool in the domestic turkey (Meleagris gallopavo)

Poultry Science, 2020
This study determined, for the first time, the different subpopulations of germ cells and stereological changes within the cortex of the functional left ovary during germ cell nest breakdown, and formation of the primordial follicle pool in the domestic ...
G.B. Hall, J.A. Long, B.J. Wood, G.Y. Bedecarrats   +3 more
doaj   +1 more source

Spermatogenesis and sertoli cell activity in mice lacking Sertoli cell receptors for follicle stimulating hormone and androgen [PDF]

, 2008
Spermatogenesis in the adult male depends on the action of FSH and androgen. Ablation of either hormone has deleterious effects on Sertoli cell function and the progression of germ cells through spermatogenesis.
A. Monteiro, Abel, Baker, Baker, Baker, Bartles, Beardsley, Boettger-Tong, Carpenter, Casteren, Cattanach, Chang, Cheng, Czechowski, De Gendt, De Gendt, Denolet, Dierich, Dym, Eacker, F. Guillou, G. Verhoeven, H. M. Charlton, Haavisto, Haywood, Heckert, Hirst, Hofmann, Holdcraft, Johnston, Jonsson, K. De Gendt, Kageyama, Kumar, Lecureuil, Lyon, M. H. Abel, Maguire, Mayhew, McLachlan, McLachlan, Meng, O’Shaughnessy, O’Shaughnessy, O’Shaughnessy, O’Shaughnessy, O’Shaughnessy, O’Shaughnessy, P. J. Baker, P. J. O’Shaughnessy, Russell, Russell, Sadate-Ngatchou, Sadate-Ngatchou, Safina, Sharpe, Singh, Sluka, Tan, Vihko, Wong, Wreford, Yang, Zhou   +63 more
core   +2 more sources

Germ Cell Proteins in Melanoma: Prognosis, Diagnosis, Treatment, and Theories on Expression

Journal of Skin Cancer, 2012
Germ cell protein expression in melanoma has been shown to correlate with malignancy, severity of disease and to serve as an immunologic target for therapy.
Ashley M. Rosa, Nitika Dabas, Diana M. Byrnes, Mark S. Eller, James M. Grichnik   +4 more
doaj   +1 more source