Results 331 to 340 of about 24,196 (383)

Malignant Mixed Germ Cell Tumors of the Ovary: An Analysis of 100 Cases Emphasizing the Frequency and Interrelationships of Their Tumor Types.

American Journal of Surgical Pathology, 2020
One hundred malignant mixed germ cell tumors of the ovary that occurred in patients 3 to 55 years (mean: 20 y) of age are described. The clinical presentation was usually that of any highly malignant tumor of the ovary (abdominal pain and distension ...
N. Safdar, J. Stall, R. Young
semanticscholar   +1 more source

Derivation and characterization of pluripotent embryonic germ cells in chicken

Molecular Reproduction and Development, 2000
Embryonic germ (EG) cell lines established from primordial germ cells (PGCs) are undifferentiated and pluripotent stem cells. To date, EG cells with proven germ-line transmission have been completely established only in the mouse with embryonic stem (ES) cells.
T S, Park, J Y, Han
openaire   +2 more sources

Further insights into testicular germ cell tumor oncogenesis: potential therapeutic targets

Expert Review of Anticancer Therapy, 2020
Introduction: Testicular germ cell tumors (TGCTs) are the most common neoplasia in the young male population, and the incidence has been constantly increasing in many parts of the world.
P. Chieffi, Marco De Martino, F. Esposito   +2 more
semanticscholar   +1 more source

[Embryonal germ cells and germ cell tumors].

Verhandlungen der Deutschen Gesellschaft fur Pathologie, 2008
Testicular germ cell tumors comprise of group of pluripotent tumors including seminomas and nonseminomas, arise from intratubular germ cell neoplasia and originate from the primordial germ cells/ gonocytes. Many well characterized markers of embryonic stem cells including CD9, PODXL and centromere-specific histone-H3-like protein CENPA are consistently
K, Biermann, L C, Heukamp, D, Nettersheim, K, Steger, H, Zhou, F E, Franke, I, Guetgemann, V, Sonnack, R, Brehm, J, Berg, P J, Bastian, S C, Müller, L, Wang-Eckert, H, Schorle, R, Büttner   +14 more
openaire   +1 more source

[Germ cell and embryonal tumors].

Der Radiologe, 2015
Germ cell tumors, which constitute approximately 3-5% of tumors of the central nervous system (CNS), can be subdivided into germinomas, embryonal carcinomas, yolk sac tumors, choriocarcinomas, teratomas and mixed germ cell tumors. The diagnosis of intracranial germ cell tumor is based on the clinical symptoms, detection of tumor markers, such as alpha ...
W, Reith, R, Mühl-Benninghaus, A, Simgen, U, Yilmaz   +3 more
openaire   +1 more source

Human Embryonic Stem Cells and Germ Cell Development

2009
Embryonic stem cells (ESCs) are derived from the inner cell mass (ICM) of blastocysts and are characterized by the ability to differentiate into the three primary germ layers. Evidence shows, however, that the cells of the ICM and derived ESCs are not identical.
Nina J. Kossack, Joerg Gromoll, Renee A. Reijo Pera   +2 more
openaire   +1 more source

Fine needle aspiration of mediastinal germ cell tumors.

Seminars in diagnostic pathology, 2020
Germ cell tumors in the mediastinum are rare and often occur in young patients but may occur in older patients. Seminoma, embryonal carcinoma, yolk sac tumor, choriocarcinoma and teratoma have distinct morphologic features with high grade nuclei.
J. Reynolds, Shiguang Liu
semanticscholar   +1 more source

Immunomagnetic Isolation of Primordial Germ Cells and the Establishment of Embryonic Germ Cell Lines in the Mouse

Cloning, 1999
The stage-specific embryonic antigen 1 (SSEA-1) is a cell marker of primordial germ cells (PGCs). In the present study, it is shown that isolation and purification of PGCs from 8.5-11.5 days post coitum (dpc) embryos can be achieved by a immunomagnetic cell sorting method using SSEA-1 antibody-conjugated magnetic beads, and then the sorted PGCs can be ...
G, Durcova-Hills, T, Tokunaga, S, Kurosaka, M, Yamaguchi, S, Takahashi, H, Imai   +5 more
openaire   +2 more sources

Differentiation and characterization of embryonic stem cells into three germ layers

Biochemical and Biophysical Research Communications, 2009
Embryonic stem cells differentiated on M15 cells have previously been shown to give rise to cells of the mesendodermal and definitive endodermal lineages. Here we demonstrate that neuroectodermal and mesodermal lineages can be derived from ES cells cultured on M15 cells and subsequently subjected to specific culture conditions, as confirmed by the ...
Shiraki N, Higuchi Y, Harada S, Umeda K, Isagawa T, Aburatani H, Kume K, Shoen Kume   +7 more
openaire   +2 more sources

Nuclear proteome analysis of undifferentiated mouse embryonic stem and germ cells

ELECTROPHORESIS, 2008
AbstractEmbryonic stem cells (ESCs) and embryonic germ cells (EGCs) provide exciting models for understanding the underlying mechanisms that make a cell pluripotent. Indeed, such understanding would enable dedifferentiation and reprogrammation of any cell type from a patient needing a cell therapy treatment.
Buhr, Nicolas, Carapito, Christine, Schaeffer, Christine, Kieffer, Emmanuelle, van Dorsselaer, Alain, Viville, Stéphane   +5 more
openaire   +4 more sources