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Pediatric malignant testicular germ cell tumors: a developmental and comparative perspective [PDF]
Diagnostic PathologyMalignant testicular germ cell tumors exhibit significant histologic diversity, particularly across pediatric age groups. Prepubertal patients more commonly develop yolk sac tumors, whereas postpubertal adolescents are more likely to present with mixed ...
Sonja Chen, Andres Matoso
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Cancer Treatment Reviews, 2008 Malignant ovarian germ cell tumors (MOGCTS) are rare but curable at all stages of disease. This review gives an outline of the management of this disease.We performed a literature search in the PubMed of almost all relevant articles concerning MOGCTs on pathology, prognostic factors, surgery, post-operative therapy and late effects of therapy.
D Pectasides, D Kassanos
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Primordial germ cell-like cells residing in the pituitary may serve as the origin of intracranial germ cell tumors [PDF]
Scientific ReportsIntracranial germ cell tumors (iGCTs) are rare, histologically classified as extragonadal germ cell tumors, and predominantly affect children and adolescents.
Yi Zhang +7 more
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Germ cell tumors in children. [PDF]
Virchows ArchPediatric germ cell tumors represent a rare but biologically diverse group of neoplasms arising from pluripotent primordial germ cells. The 2022 edition of the WHO Classification of Pediatric Tumors introduced the first organ independent classification of germ cell tumors, reflecting advances in molecular biology, histopathology, and clinical practice.
Bode PK +3 more
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Spermatocytic tumor – case report [PDF]
Liječnički vjesnik, 2021 According to the newest WHO classification tumors of the testis are divided into germ cell tumors derived from germ cell neoplasia in situ, germ cell tumors unrelated to germ cell neoplasia in situ, sex cord-stromal tumors, tumors containing both germ ...
Tonći Vodopić +5 more
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To Be or Not to Be a Germ Cell: The Extragonadal Germ Cell Tumor Paradigm [PDF]
International Journal of Molecular Sciences, 2021 In the human embryo, the genetic program that orchestrates germ cell specification involves the activation of epigenetic and transcriptional mechanisms that make the germline a unique cell population continuously poised between germness and pluripotency. Germ cell tumors, neoplasias originating from fetal or neonatal germ cells, maintain such dichotomy
Massimo De Felici +5 more
openaire +6 more sources
Extragonadal Germ Cell Tumors in Children and Adolescents - a 20 Year Study [PDF]
Modern Medicine, 2020 Germ cell tumors (GCTs) are rare neoplasms which are seen in all age groups and both sexes. GCTs in the pediatric age group show considerable variation from their adult counterparts in relation to site, histological type, clinical and radiological ...
Felice FAIZAL +2 more
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Rare Intracranial Multifocal Non-Germinomatous Germ Cell Tumor in an 18-Year-Old Male: A Case Report
Acta Clinica Croatica, 2023 Intracranial germ cell tumors are rare brain tumors that are distinguished based on their histology and selected tumor markers. Non-germinomatous germ cell tumors are a diverse group of such tumors having the poorest prognosis.
Nikolina Sesar +3 more
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Treatment of Germ Cell Testicular Cancer
Acta Clinica Croatica, 2020 Germ-cell testicular cancer (GCTC) is a malignant neoplasm derived from the primordial germ cell. Although it accounts for approximately 1% of all malignancies in men, it is the most common cancer of younger male population, with the highest incidence ...
Ana Koši Kunac +3 more
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