Results 121 to 130 of about 1,853,912 (306)

Peripheral Blood DNA Methylation Changes Precede Lymphoma Diagnosis in Primary Sjögren's Disease

Arthritis &Rheumatology, EarlyView.
Objective Primary Sjögren's disease (SjD) is a systemic autoimmune disease associated with an increased risk of lymphoma. The molecular mechanisms underlying lymphomagenesis remain poorly understood, and sensitive biomarkers for early identification of patients at high risk of developing lymphoma are lacking.
Hanna Lidberg, Cecilia Fugmann, Juliana Imgenberg‐Kreuz   +2 more
wiley   +1 more source

Mature mediastinal teratoma with adhesions to the pericardium: A rare case report

Clinical Case Reports
Key Clinical Message Mature mediastinal teratoma (MMT) is a benign tumor that is composed of well‐differentiated tissues from all three germ cell layers. Malignant tumors have a distinct feature of adhering to the surrounding organs.
Somar Mansour, Ali Badr, Majd Mansour, Mouhamad Badr, Ali Afif, Samer Rajab, Zuheir Alshehabi   +6 more
doaj   +1 more source

Long-term toxicity of cisplatin in germ-cell tumor survivors

Annals of Oncology, 2017
Michal Chovanec, Michal Chovanec, M. Zaid, Nasser H. Hanna, N. El-Kouri, Lawrence H. Einhorn, C. Albany   +6 more
semanticscholar   +1 more source

Age‐associated B cells contribute to inflammation via antibody‐independent mechanisms in Takayasu's arteritis

Arthritis &Rheumatology, Accepted Article.
Objective Although Takayasu's arteritis (TAK) is not a prototypical autoantibody‐mediated disease, accumulating evidence suggests that B cells are involved. This study aimed to investigate the pathway of B‐cell activation and its contributions to TAK pathogenesis.
Chenglong Fang, Xiaoxi Yang, Xiaochuan Sun, Shangyi Jin, Lihong Du, Jinwei Gao, Jing Li, Zhen Chen, Yuexin Chen, Mengtao Li, Xinping Tian   +10 more
wiley   +1 more source

A Case Report of Giant Cell Tumor of the Tendon Sheath after Treatment of Germ Cell Tumor of Testicles in a 7-year-old boy

Journal of Mazandaran University of Medical Sciences, 2020
Germ cell tumors account for 2 to 3% of all cancers in children. These tumors appear in the testicles as painless masses. The primary treatment of these tumors is the removal of testicles and chemotherapy. Giant cell tumor of the tendon sheath (GCTTS) is
Hossin Karami, Mohammad Naderisorki, Laleh Vahedi Larijani   +2 more
doaj  

Synergistic Enhancement of Antioxidant Activity in Arbutus unedo Leaf Extract by Biological Fluids: Implications for Functional and Nutraceutical Applications

Biotechnology and Applied Biochemistry, EarlyView.
ABSTRACT This study examined the effect of biological fluids (saliva, blood plasma, and urine) on the antioxidant capacity of an aqueous extract derived from Arbutus unedo leaves. The extract displayed a concentration‐dependent reducing activity in the ferric reducing power assay (IC50 = 292 ± 7.54 µg/mL) and phosphomolybdenum assays (IC50 = 461.67 ± 4.
Idir Moualek, Hamdi Bendif, Karima Benarab, Giulio Lupidi, Fehmi Boufahja, Stefania Garzoli, Karim Houali   +6 more
wiley   +1 more source

Burned-out testis tumor revealed by inguinal lymphadenopathy

Urology Research and Practice, 2019
Metastatic testicular germ cell tumors with complete involution of the primary site (i.e. burned-out tumor) are rare entities. In this study, we report a case of testicular germ cell tumor with inguinal lymph node metastasis.
Nil Çulhacı, Haluk Erol, İbrahim Meteoğlu, Hicran Turhan, Mehmet Dündar   +4 more
doaj   +2 more sources

Clinical Relevance of HER-2/neu Overexpression in Patients With Testicular Nonseminomatous Germ Cell Tumor

Urology Journal, 2010
Introduction: Recent scientific attention has focused on the role of growth factors in the progression of cancer. HER-2/neu is an epidermal growth factor receptor that is demonstrated to have correlation with poor prognosis of many cancers.
Mohammad Reza Ghavamnasiri, Hamid Saeedi Saedi, Soodabeh Shahid Sales, Kamran Ghafarzadegan   +3 more
doaj  

Metabolomic investigation of cisplatin‐induced acute kidney injury in paediatric cancer patients

British Journal of Clinical Pharmacology, EarlyView.
Aim Cisplatin causes acute kidney injury (AKI) in approximately 46% of paediatric cancer patients who receive it. Serum creatinine (SCr) is a poor biomarker of cisplatin nephrotoxicity, because there is a delay between cisplatin infusion and SCr elevation.
Yong Jin Lim, Amy Thachil, Kelly McMahon, Ross T. Tsuyuki, S. Rod Rassekh, Lesley G. Mitchell, Prasad Devarajan, Cherry Mammen, Bruce C. Carleton, Geoffrey D. E. Cuvelier, Victor A. Lewis, Colin J. D. Ross, Alexandra P. Zorzi, Sylvain Baruchel, Raveena Ramphal, Eric Bouffet, Mathieu Lemaire, Tom D. Blydt‐Hansen, Brad L. Urquhart, The Applying Biomarkers to Minimize Long‐Term Effects of Childhood/Adolescent Cancer Treatment (ABLE) Research Study Group, Tom Blydt‐Hansen, Bruce C. Carleton, Geoff D. E. Cuvelier, Sunil Desai, Prasad Devarajan, Conrad Fernandez, Adam Fleming, Paul Gibson, Caroline Laverdiere, Victor Lewis, Mary L. McBride, Bruno Michon, Shahrad Rod Rassekh, Colin J. D. Ross, Christine Sabapathy, Kirk R. Schultz, Michael Zappitelli, Alexandra Zorzi   +37 more
wiley   +1 more source

From pathogen to “living drug factory” innovative strategies and clinical translation of bacteria as programmable intelligent vectors for cancer therapy

BMEMat, EarlyView.
Engineered bacteria serve as smart, living therapeutics that target tumors, deliver drugs, and remodel immunosuppressive microenvironments. This review highlights their potential to potentiate immunotherapy, radiotherapy, and chemotherapy, offering a promising paradigm for precise and synergistic cancer treatment. Abstract The dynamic interplay between
Haonan Shen, Weichen Zhang, Gaoli Niu, Li Wang, Ruiyan Li, Yueyue Fan, Feixue Lu, Lingling Xu, Xiaoyuan Ji, Yong Kang   +9 more
wiley   +1 more source