Results 21 to 30 of about 1,521,712 (329)
BackgroundUnlike young and middle-aged patients, seminoma is not common in patients with primary testicular tumors over the age of 50, so it cannot follow the general ideas and norms for diagnosing and treating testicular tumors, and its characteristics ...
Nianyu Xue+3 more
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Human Germ Cell Tumors are Developmental Cancers: Impact of Epigenetics on Pathobiology and Clinic
Current (high throughput omics-based) data support the model that human (malignant) germ cell tumors are not initiated by somatic mutations, but, instead through a defined locked epigenetic status, representative of their cell of origin.
J. Lobo+4 more
semanticscholar +1 more source
Primary Germ Cell Tumors of the Mediastinum: 10 Years of Experience in a Tertiary Teaching Hospital
Germ cell tumors occur mostly in the gonad. Extragonadal germ cell tumors are rare, and most occur in the retroperitoneum and mediastinum. Primary mediastinal germ cell tumors are often found in the anterior portion of the mediastinum and include ...
Chih-Jen Yang+2 more
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Extragonadal germ cell tumor, a report of two cases presenting in the gastrointestinal tract
Germ cell tumors are a heterogeneous group of tumors that can present primarily as gonadal tumors in either a localized or metastatic pattern. Rarely these tumors can initially present at extra-gonadal locations, including the gastrointestinal tract.
Mousa Elkhaldi+3 more
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Prognosis of 26 children with intracranial germ-cell tumors (17 germinomas and 9 teratomas) treated in a 10 year period is reported from the University Hospital Hamburg-Eppendorf, Germany.
J Gordon Millichap
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Germ cell tumors of ovary with elements of two or more subtypes are relatively uncommon. Sarcoid-like granulomas are seen in rare association with dysgerminomas, a subgroup of germ cell tumors of ovary, which are again less common. Fine-needle aspiration
Reshma S Davanageri+5 more
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Pediatric Germ Cell Tumors: A Developmental Perspective
Germ cell tumors (GCTs) arising in infants, children, and adolescents present a set of special challenges. GCTs make up about 3% of malignancies in children aged 0–18 and nearly 15% of cancers in adolescents. Epidemiologic and molecular evidence suggests
J. Pierce, A. L. Frazier, J. Amatruda
semanticscholar +1 more source
On the Origin of Testicular Germ Cell Tumors: From Gonocytes to Testicular Cancer
Human primordial germ cells (PGCs) have been described in the yolk sac wall around the beginning of the third week. From week 4 to 5, they migrate under control of SCF/c-KIT signaling pathway to the genital ridge, where they become gonocytes.
T. Baroni+4 more
semanticscholar +1 more source
A Rare Case of Primary Anterior Mediastinal Yolk Sac Tumor in an Elderly Adult Male
Mediastinal germ cell tumors are extragonadal germ cell tumors (EGGCTs) commonly seen in children and young adults. They are more common in men. Clinically they are classified as teratomas, seminomas, and nonseminomatous germ cell tumors.
Sammy G. Nakhla, Srinath Sundararajan
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Mixed germ cell tumors: Report of two cases
Germ cell tumors arise in the ovaries and testis and rarely in other tissues. Mixed germ cell tumors are rare. We report two cases of mixed germ cell tumors, one consisting of seminoma and immature teratoma in the testis of a 30-year-old male and second ...
Pradhan M Pagaro+3 more
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